Detalhe da pesquisa
1.
Systematic synthetic and biophysical development of mixed sequence DNA binding agents.
Org Biomol Chem
; 15(4): 827-835, 2017 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27995240
2.
Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair.
Bioorg Med Chem Lett
; 25(21): 4927-4932, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26051649
3.
Selective G-quadruplex DNA recognition by a new class of designed cyanines.
Molecules
; 18(11): 13588-607, 2013 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24192912
4.
Binding to the DNA Minor Groove by Heterocyclic Dications: from AT Specific to GC Recognition Compounds.
Curr Protoc
; 3(4): e729, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37071034
5.
"Stapling" scFv for multispecific biotherapeutics of superior properties.
MAbs
; 15(1): 2195517, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37074212
6.
Correlation of local effects of DNA sequence and position of ß-alanine inserts with polyamide-DNA complex binding affinities and kinetics.
Biochemistry
; 51(49): 9796-806, 2012 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23167504
7.
Dynamics of bleomycin interaction with a strongly bound hairpin DNA substrate, and implications for cleavage of the bound DNA.
J Am Chem Soc
; 134(43): 17842-5, 2012 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23072568
8.
A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines.
Bioorg Med Chem Lett
; 22(18): 5984-8, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22889802
9.
Halogenated pentamethine cyanine dyes exhibiting high fidelity for G-quadruplex DNA.
Bioorg Med Chem
; 20(24): 7002-11, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23127491
10.
Discovery and pharmacological characterization of cetrelimab (JNJ-63723283), an anti-programmed cell death protein-1 (PD-1) antibody, in human cancer models.
Cancer Chemother Pharmacol
; 89(4): 515-527, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35298699
11.
Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents.
Bioorg Med Chem
; 19(2): 978-84, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21194955
12.
Teclistamab is an active T cell-redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma.
Blood Adv
; 4(18): 4538-4549, 2020 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32956453
13.
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
J Alzheimers Dis
; 77(4): 1397-1416, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32894244
14.
Biosensor-Surface Plasmon Resonance: Label-Free Method for Investigation of Small Molecule-Quadruplex Nucleic Acid Interactions.
Methods Mol Biol
; 2035: 63-85, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31444744
15.
Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands.
Bioorg Med Chem Lett
; 18(5): 1668-73, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18243701
16.
Human IgG subclass cross-species reactivity to mouse and cynomolgus monkey Fcγ receptors.
Immunol Lett
; 197: 1-8, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29476755
17.
Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody.
Mol Metab
; 10: 87-99, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29453154
18.
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo.
J Alzheimers Dis
; 65(1): 265-281, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30040731
19.
Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance.
Diabetes
; 66(1): 206-217, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27797911
20.
Discovery of new G-quadruplex binding chemotypes.
Chem Commun (Camb)
; 50(8): 960-3, 2014 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24302123