Botanicals as promising antimicrobial agents for enhancing oral health: a comprehensive review.

The mouth houses the second largest diversity of microorganisms in the body, harboring more than 700 bacterial species colonizing the soft mucosa and hard tooth surfaces. Microbes are the cause of several health-related problems, such as dental carries, gingivitis, periodontitis, etc., in the mouth across different age groups and socioeconomic/demographic groups. Oral infections are major health problems that affect the standard of living. Compromised oral health is related to chronic conditions and systemic disorders. Microbes responsible for dental caries are acid-producing and aciduric Gram-positive bacteria (Streptococci, Lactobacilli). Gram-negative bacteria (Porphyromonas, Prevotella, Actinobacillus, and Fusobacterium) capable of growing in anaerobic environments are responsible for periodontal diseases. Due to the high prevalence of oral diseases, negative effects associated with the use of antimicrobial agents and increased antibiotic resistance in oral pathogens, suitable alternative methods (effective, economical and safe) to suppress microbes disturbing oral health need to be adopted. Side effects associated with the chemical antimicrobial agents are vomiting, diarrhea and tooth staining. Several researchers have studied the antimicrobial properties of plant extracts and phytochemicals and have used them as indigenous practices to control several infections. Therefore, phytochemicals extracted from plants can be suitable alternatives. This review focuses on the various phytochemical/plant extracts suppressing the growth of oral pathogens either by preventing their attachment to the surfaces or by preventing biofilm formation or other mechanisms.

Bioprospecting plant growth-promoting rhizobacteria from rice genotypes and their influence on growth under aerobic conditions.

The bacteria that colonize plant roots and enhance plant growth by various mechanisms are known as plant growth-promoting rhizobacteria (PGPR). The functions of rhizobacteria stand substantially unexplored and detailed insights into the aerobic rice ecosystem are yet to be examined. In this study, we have isolated rhizobacteria from rice varieties grown under aerobic conditions. Seed germination test showed that strain Ekn 03 was significantly effective in stimulating germination, enhancing shoot and root length, and increasing dry matter accumulation in treated rice plants as compared to the uninoculated plants. Under greenhouse conditions, strain Ekn 03 treated rice varieties showed an overall increase in plant height by 7.63%, dry matter accumulation by 16.23%, and total chlorophyll content by 76.47%. Soil acetylene reduction assay (ARA) (4.17 nmole ethylene/g soil/h) and in-planta ARA (4.2 × 10-2 nmole ethylene/mg fresh weight of plant/h) was significantly higher in Ekn 03 treated rice variety PB 1509 under aerobic conditions. Other rice varieties showed comparable performance on inoculation with strain Ekn 03. The endophytic and rhizospheric population of antibiotic tagged Ekn 03 was higher in the roots of PB 1509 (1.02 × 104 cfu/g and 5.8 × 105 cfu/g soil, respectively) compared to other rice varieties. 16S rDNA sequence analysis revealed that strain Ekn 03 was having 100% similarity with Pseudomonas protegens. This study suggests that strain Ekn 03 can be used as a microbial inoculant in rice plants under aerobic system of cultivation. This is the first report on the application of P. protegens as PGPR in rice.

Software implementation of systematic polar encoding based PKC-SPE cryptosystem for quantum cybersecurity.

The ever-growing threats in cybersecurity growing with the rapid development of quantum computing, necessitates the development of robust and quantum-resistant cryptographic systems. This paper introduces a novel cryptosystem, Public Key Cryptosystem based on Systematic Polar Encoding (PKC-SPE), based on the combination of systematic polar encoding and public-key cryptographic principles. The Systematic Polar Encoding (SPE), derived from the well-established field of polar codes, serves as the foundation for this proposed cryptographic scheme. Here, we have used MATLAB Software to introduce and implement the PKC-SPE Cryptosystem. The paper examines key generation, encryption, and decryption algorithms, providing insights into the adaptability and efficiency of systematic polar encoding in public-key cryptography. We assess the efficiency of the PKC-SPE Cryptosystem in three aspects: key size, computational complexity, and system implementation timings. In addition, we compare the PKC-SPE Cryptosystem with PKC-PC cryptosystem and find that it has reduced key sizes ( P r = 0.8436 kbytes). The results obtained through simulations validate the effectiveness of the proposed cryptosystem and highlighting its potential for integration into real-world communication systems. Thus, in the paradigm shift to quantum computing, the PKC-SPE cryptosystem emerges as a promising candidate to secure digital communication in the quantum computing era.