Detalhe da pesquisa
1.
Na+ controls hypoxic signalling by the mitochondrial respiratory chain.
Nature
; 586(7828): 287-291, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728214
2.
Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs.
PLoS Genet
; 16(2): e1008549, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32012164
3.
Multi-omic insights into Parkinson's Disease: From genetic associations to functional mechanisms.
Neurobiol Dis
; 163: 105580, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871738
4.
Central Activation of Alpha7 Nicotinic Signaling Attenuates LPS-Induced Neuroinflammation and Sickness Behavior in Adult but Not in Aged Animals.
Molecules
; 26(8)2021 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33916910
5.
The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca2+ dysregulation, and mitochondrial abnormalities.
J Neurochem
; 145(2): 170-182, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29315575
6.
Sequential activation of microglia and astrocyte cytokine expression precedes increased Iba-1 or GFAP immunoreactivity following systemic immune challenge.
Glia
; 64(2): 300-16, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26470014
7.
Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca(2+) release from the endoplasmic reticulum.
J Neurochem
; 133(3): 309-19, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25650007
8.
A new mutation in the Parkinson's-related FBXO7 gene impairs mitochondrial and proteasomal function.
FEBS J
; 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38708447
9.
The Cannabigerol Derivative VCE-003.2 Exerts Therapeutic Effects in 6-Hydroxydopamine-Lesioned Mice: Comparison with The Classic Dopaminergic Replacement Therapy.
Brain Sci
; 13(9)2023 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37759872
10.
Endocannabinoid-Binding Receptors as Drug Targets.
Methods Mol Biol
; 2576: 67-94, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152178
11.
Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.
medRxiv
; 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38076956
12.
Transcriptome deregulation of peripheral monocytes and whole blood in GBA-related Parkinson's disease.
Mol Neurodegener
; 17(1): 52, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35978378
13.
Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies.
Nat Genet
; 54(1): 4-17, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34992268
14.
Dysregulation of mitochondrial and proteolysosomal genes in Parkinson's disease myeloid cells.
Nat Aging
; 1(9): 850-863, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35005630
15.
[Prevalence and profile of the frail population in La Palma, Canary Islands]. / Prevalencia y perfil de la persona frágil en la isla de La Palma.
Rev Esp Geriatr Gerontol
; 54(3): 129-135, 2019.
Artigo
em Espanhol
| MEDLINE | ID: mdl-30777385
16.
Heme-Oxygenase I and PCG-1α Regulate Mitochondrial Biogenesis via Microglial Activation of Alpha7 Nicotinic Acetylcholine Receptors Using PNU282987.
Antioxid Redox Signal
; 27(2): 93-105, 2017 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27554853
17.
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia.
Redox Biol
; 12: 1040-1051, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28511347
18.
Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases.
Pharmacol Ther
; 157: 84-104, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26617217
19.
Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice.
Mol Neurobiol
; 53(5): 3030-3045, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25966970
20.
Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection.
Biochem Pharmacol
; 97(4): 463-472, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232730