Detalhe da pesquisa
1.
The predictive distribution of the residual variability in the linear-fixed effects model for clinical cross-over trials.
Biom J
; 58(4): 797-809, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27003464
2.
Mechanisms underlying benign and reversible unconjugated hyperbilirubinemia observed with faldaprevir administration in hepatitis C virus patients.
J Pharmacol Exp Ther
; 351(2): 403-12, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25204339
3.
Faldaprevir combined with pegylated interferon alfa-2a and ribavirin in treatment-naïve patients with chronic genotype 1 HCV: SILEN-C1 trial.
Hepatology
; 57(6): 2143-54, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23359516
4.
Faldaprevir combined with peginterferon alfa-2a and ribavirin in chronic hepatitis C virus genotype-1 patients with prior nonresponse: SILEN-C2 trial.
Hepatology
; 57(6): 2155-63, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23504636
5.
Antiviral effect, safety, and pharmacokinetics of five-day oral administration of Deleobuvir (BI 207127), an investigational hepatitis C virus RNA polymerase inhibitor, in patients with chronic hepatitis C.
Antimicrob Agents Chemother
; 57(10): 4727-35, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23856779
6.
Oral bioavailability of dabigatran etexilate (Pradaxa(®) ) after co-medication with verapamil in healthy subjects.
Br J Clin Pharmacol
; 75(4): 1053-62, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22946890
7.
Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection.
Gastroenterology
; 141(6): 2047-55; quiz e14, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21925126
8.
Decrease in the oral bioavailability of dabigatran etexilate after co-medication with rifampicin.
Br J Clin Pharmacol
; 74(3): 490-500, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22348256
9.
Safety, pharmacokinetics and antiviral effect of BILB 1941, a novel hepatitis C virus RNA polymerase inhibitor, after 5 days oral treatment.
Antivir Ther
; 14(1): 23-32, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19320234
10.
Bayesian Phase II optimization for time-to-event data based on historical information.
Stat Methods Med Res
; 28(4): 1272-1289, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29284369
11.
Response to the letter by Dr Chin and co-workers.
Br J Clin Pharmacol
; 75(2): 556, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23302070
12.
Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study).
Am J Cardiol
; 100(9): 1419-26, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17950801
13.
Viral kinetics in patients with chronic hepatitis C treated with the serine protease inhibitor BILN 2061.
Antivir Ther
; 11(3): 371-6, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16759054
14.
An open-label study of the pharmacokinetics and pharmacodynamics of dabigatran etexilate 150mg once daily in Caucasian patients with moderate renal impairment undergoing primary unilateral elective total knee or hip replacement surgery.
Thromb Res
; 144: 158-64, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27352238
15.
Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement.
J Clin Pharmacol
; 45(5): 555-63, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15831779
16.
The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy).
J Am Coll Cardiol
; 63(4): 321-8, 2014 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076487
17.
Empagliflozin (BI 10773), a Potent and Selective SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects.
Clin Pharmacol Drug Dev
; 2(2): 152-61, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27121669
18.
Faldaprevir (BI 201335), deleobuvir (BI 207127) and ribavirin oral therapy for treatment-naive HCV genotype 1: SOUND-C1 final results.
Antivir Ther
; 18(8): 1015-9, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23558093
19.
Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C.
Hepatology
; 41(4): 832-5, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15732092
20.
Pharmacokinetics and pharmacodynamics of terbogrel, a combined thromboxane A2 receptor and synthase inhibitor, in healthy subjects.
Br J Clin Pharmacol
; 58(1): 40-51, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15206991