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1.
Front Radiat Ther Oncol ; 40: 162-178, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17641508

RESUMO

Helical tomotherapy is a volumetric image-guided, fully dynamic, intensity-modulated radiation therapy (IMRT) delivery system. The daily use of its pretreatment megavoltage (MV) CT imaging for patient setup verification allows one to correct for interfraction setup error. This is a primary requirement for the accurate delivery of complex IMRT treatment plans, which give differential radiation doses to various target volumes while conformally avoiding normal critical structures. In particular, image guidance using MV CT allows for direct target position verification with the patient in the actual treatment position just prior to therapy delivery. Moreover, since helical MV CT imaging is a slow CT imaging technique, it allows for the encoding of target motion in the resulting MV CT data set, and therefore the pretreatment verification of a motion envelope defined from four-dimensional CT.


Assuntos
Radioterapia de Intensidade Modulada/métodos , Tomografia Computadorizada Espiral/métodos , Fracionamento da Dose de Radiação , Humanos , Dosagem Radioterapêutica
2.
Brachytherapy ; 5(1): 56-60, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16563998

RESUMO

PURPOSE: Quality assurance for complex high-dose-rate (HDR) treatment planning has always been a challenge to the physics community because of the time constraint between HDR planning and the delivery of the treatment. This study proposes an efficient, precise, and easy method for checking the complex computer calculation. METHODS AND MATERIALS: Posttreatment, three-dimensional dose-volume study was performed for 98 patients with 128 new treatment plans along with 30 library plans. Volumes covered by the 100% isodose line, source activity (Ci), total dwell time (s), and the prescription dose (100%) were recorded. Variation of R(V) defined as (irradiated time x activity/elongation factor x prescribed dose) with volume was studied for different catheter systems. RESULTS: Parametric fit of R(V) with volume for three different systems that cover most of the interstitial and intracavitary brachytherapy implants agrees within +/-6%. CONCLUSIONS: The excellent agreement of R(V) derived from this simplistic point source model with three-dimensional dose calculations for individual HDR treatment plans clearly establishes that for an implant with known number of catheters, the time needed to deliver a prescribed dose to a given prescription volume can be easily predicted.


Assuntos
Braquiterapia/métodos , Neoplasias da Mama/radioterapia , Garantia da Qualidade dos Cuidados de Saúde , Planejamento da Radioterapia Assistida por Computador/normas , Neoplasias do Colo do Útero/radioterapia , Feminino , Humanos , Resultado do Tratamento
3.
Appl Opt ; 44(15): 3098-104, 2005 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-15929304

RESUMO

We describe a method to frequency narrow multielement high-power diode bars. Using a commercial 60-W, 49-element, 1-cm-long diode array bar at 795 nm running at 45 W, we narrow the linewidth from 1000 to 64 GHz with only a loss of 33% in output power. The resulting laser light is well suited for spin-exchange optical pumping of noble gas nuclei.


Assuntos
Lasers , Iluminação/instrumentação , Semicondutores , Desenho de Equipamento , Análise de Falha de Equipamento , Luz , Iluminação/métodos
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