Detalhe da pesquisa
1.
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
Nature
; 593(7859): 424-428, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33767445
2.
Reactivation of the G1 enhancer landscape underlies core circuitry addiction to SWI/SNF.
Nucleic Acids Res
; 52(1): 4-21, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993417
3.
Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors.
Bioorg Med Chem Lett
; 97: 129567, 2024 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38008339
4.
Coronaviral RNA-methyltransferases: function, structure and inhibition.
Nucleic Acids Res
; 50(2): 635-650, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35018474
5.
Novel analogues of a nonnucleoside SARS-CoV-2 RdRp inhibitor as potential antivirotics.
Beilstein J Org Chem
; 20: 1029-1036, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38746653
6.
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein.
PLoS Pathog
; 16(12): e1009100, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33264373
7.
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold.
Bioorg Med Chem Lett
; 76: 129010, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36184029
8.
Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
Nature
; 597(7874): E2, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34345019
9.
High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses.
Molecules
; 26(13)2021 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34206406
10.
Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angew Chem Int Ed Engl
; 60(18): 10172-10178, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33616279
11.
Structural analysis of the putative SARS-CoV-2 primase complex.
J Struct Biol
; 211(2): 107548, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32535228
12.
Optimization of norbornyl-based carbocyclic nucleoside analogs as cyclin-dependent kinase 2 inhibitors.
J Mol Recognit
; 33(8): e2842, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32212222
13.
Could 5'-N and S ProTide analogues work as prodrugs of antiviral agents?
Bioorg Med Chem Lett
; 30(4): 126897, 2020 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31882298
14.
A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha.
J Lipid Res
; 60(3): 683-693, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30626625
15.
Viral RNA-Dependent RNA Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Prevents Death in a Mouse Model of West Nile Virus Infection.
Antimicrob Agents Chemother
; 63(3)2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30642926
16.
The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine.
Nucleic Acids Res
; 45(9): 5231-5242, 2017 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334993
17.
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß.
Angew Chem Int Ed Engl
; 58(46): 16617-16628, 2019 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31454140
18.
Escape of Tick-Borne Flavivirus from 2'-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness.
J Virol
; 91(21)2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28814513
19.
Synthesis of tRNA analogues containing a terminal ribose locked in the South conformation to study tRNA-dependent enzymes.
Org Biomol Chem
; 16(11): 1903-1911, 2018 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29484333
20.
Control of α/ß Anomer Formation by a 2',5' Bridge: Toward Nucleoside Derivatives Locked in the South Conformation.
J Org Chem
; 82(21): 11337-11347, 2017 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972760