Sailing Droplets in Superheated Granular Layer.

We report instability of a superheated granular layer when a droplet is deposited on top of the layer. We find that the instability caused by evaporating vapor may trap or cause the droplet to sail away from the deposited position. The sailing motion is triggered by an unstable pressure distribution originated from fast fluidization of metallic grains. We provide a predictive model and experimental verification of the enabling conditions for sailing motion based on limiting criteria for fast fluidization.

Critical heat flux enhancement in pool boiling through increased rewetting on nanopillar array surfaces.

Boiling is a key heat transfer process for a variety of power generation and thermal management technologies. We show that nanopillar arrays fabricated on a substrate enhance both the critical heat flux (CHF) and the critical temperature at CHF of the substrate and thus, effectively increase the limit of boiling before the boiling crisis is triggered. We reveal that the enhancement in both the CHF and the critical temperature results from an intensified rewetting process which increases with the height of nanopillars. We develop a predictive model based on experimental measurements of rewetting velocity to predict the enhancement in CHF and critical temperature of the nanopillar substrates. This model is critical for understanding how to control boiling enhancement and designing various nanostructured surfaces into specific applications.

Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future.

BACKGROUND: Sepsis is a major reason for intensive care unit (ICU) admission, also in resource-poor settings. ICUs in low- and middle-income countries (LMICs) face many challenges that could affect patient outcome. AIM: To describe differences between resource-poor and resource-rich settings regarding the epidemiology, pathophysiology, economics and research aspects of sepsis. We restricted this manuscript to the ICU setting even knowing that many sepsis patients in LMICs are treated outside an ICU. FINDINGS: Although many bacterial pathogens causing sepsis in LMICs are similar to those in high-income countries, resistance patterns to antimicrobial drugs can be very different; in addition, causes of sepsis in LMICs often include tropical diseases in which direct damaging effects of pathogens and their products can sometimes be more important than the response of the host. There are substantial and persisting differences in ICU capacities around the world; not surprisingly the lowest capacities are found in LMICs, but with important heterogeneity within individual LMICs. Although many aspects of sepsis management developed in rich countries are applicable in LMICs, implementation requires strong consideration of cost implications and the important differences in resources. CONCLUSIONS: Addressing both disease-specific and setting-specific factors is important to improve performance of ICUs in LMICs. Although critical care for severe sepsis is likely cost-effective in LMIC setting, more detailed evaluation at both at a macro- and micro-economy level is necessary. Sepsis management in resource-limited settings is a largely unexplored frontier with important opportunities for research, training, and other initiatives for improvement.