Detalhe da pesquisa
1.
Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models.
J Cell Sci
; 136(6)2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36912451
2.
TAK1 inhibition elicits mitochondrial ROS to block intracellular bacterial colonization.
Proc Natl Acad Sci U S A
; 118(25)2021 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161265
3.
Coordinating Tissue Regeneration Through Transforming Growth Factor-ß Activated Kinase 1 Inactivation and Reactivation.
Stem Cells
; 37(6): 766-778, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30786091
4.
Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death.
Genesis
; 56(3): e23093, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29411501
5.
TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus.
J Cell Sci
; 129(9): 1855-65, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26985063
6.
Tak1, Smad4 and Trim33 redundantly mediate TGF-ß3 signaling during palate development.
Dev Biol
; 398(2): 231-41, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25523394
7.
Inhibition of autophagy by TAB2 and TAB3.
EMBO J
; 30(24): 4908-20, 2011 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22081109
8.
Epithelial transforming growth factor ß-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species.
Proc Natl Acad Sci U S A
; 109(9): 3365-70, 2012 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22331902
9.
TGF-ß-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells.
J Biol Chem
; 288(19): 13467-80, 2013 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23546880
10.
TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration.
Blood
; 120(18): 3846-57, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22972987
11.
TGF-beta-activated kinase 1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium.
J Immunol
; 185(8): 4729-37, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855879
12.
Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway.
J Biol Chem
; 285(4): 2333-9, 2010 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19955178
13.
Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis.
J Immunol
; 181(2): 1143-52, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18606667
14.
Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing.
J Cell Biol
; 218(6): 1994-2005, 2019 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975711
15.
Generation of a conditional mutant allele for Tab1 in mouse.
Genesis
; 46(8): 431-9, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18693278
16.
Osmotic stress blocks NF-kappaB-dependent inflammatory responses by inhibiting ubiquitination of IkappaB.
FEBS Lett
; 581(29): 5549-54, 2007 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-17997988
17.
AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.
Circ Res
; 97(9): 872-9, 2005 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16179588
18.
Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.
Mol Cell Biol
; 23(4): 1379-89, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12556497
19.
TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling.
Mol Cell Biol
; 23(4): 1231-8, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12556483
20.
Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol.
Mol Cell Biol
; 22(20): 7158-67, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12242293