Detalhe da pesquisa
1.
Complexity of phenotypes induced by p.Asn1303Lys-CFTR correlates with difficulty to rescue and activate this protein.
Cell Mol Biol (Noisy-le-grand)
; 63(11): 106-110, 2017 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29208182
2.
SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.
Biochim Biophys Acta
; 1853(5): 892-903, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25661196
3.
Missense mutations in SLC26A8, encoding a sperm-specific activator of CFTR, are associated with human asthenozoospermia.
Am J Hum Genet
; 92(5): 760-6, 2013 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23582645
4.
Pushing the limits of catalytic C-H amination in polyoxygenated cyclobutanes.
Org Biomol Chem
; 14(9): 2780-96, 2016 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26860404
5.
ANO1 contributes to angiotensin-II-activated Ca2+-dependent Cl- current in human atrial fibroblasts.
J Mol Cell Cardiol
; 68: 12-9, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24412532
6.
The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation.
Hum Mol Genet
; 21(6): 1287-98, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22121115
7.
Bronchorelaxation of the human bronchi by CFTR activators.
Pulm Pharmacol Ther
; 27(1): 38-43, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23827485
8.
Rescue of functional CFTR channels in cystic fibrosis: a dramatic multivalent effect using iminosugar cluster-based correctors.
Chembiochem
; 14(15): 2050-8, 2013 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24038832
9.
C-branched iminosugars: α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP compared to miglitol and miglustat.
J Org Chem
; 78(15): 7380-97, 2013 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23688199
10.
CFTR mutation combinations producing frequent complex alleles with different clinical and functional outcomes.
Hum Mutat
; 33(11): 1557-65, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22678879
11.
Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis.
Am J Respir Cell Mol Biol
; 44(1): 83-90, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20203293
12.
Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.
Org Biomol Chem
; 9(15): 5373-88, 2011 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21512716
13.
4-C-Me-DAB and 4-C-Me-LAB - enantiomeric alkyl-branched pyrrolidine iminosugars - are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group.
Tetrahedron Lett
; 52(2): 219-223, 2011 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21157573
14.
A cystic fibrosis respiratory epithelial cell chronically treated by miglustat acquires a non-cystic fibrosis-like phenotype.
Am J Respir Cell Mol Biol
; 41(2): 217-25, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19131642
15.
Rescue of functional F508del cystic fibrosis transmembrane conductance regulator by vasoactive intestinal peptide in the human nasal epithelial cell line JME/CF15.
J Pharmacol Exp Ther
; 331(1): 2-13, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19584307
16.
Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells.
Exp Cell Res
; 314(11-12): 2199-211, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18570918
17.
Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR.
Cell Calcium
; 43(2): 175-83, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17590432
18.
Proteasome-dependent pharmacological rescue of cystic fibrosis transmembrane conductance regulator revealed by mutation of glycine 622.
J Pharmacol Exp Ther
; 325(1): 89-99, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18230692
19.
Transient receptor potential vanilloid 1 (TRPV1) channels in cultured rat Sertoli cells regulate an acid sensing chloride channel.
Biochem Pharmacol
; 75(2): 476-83, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17945192
20.
Abnormal spatial diffusion of Ca2+ in F508del-CFTR airway epithelial cells.
Respir Res
; 9: 70, 2008 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-18973672