Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes.

Madabhushi, Ram; Gao, Fan; Pfenning, Andreas R; Pan, Ling; Yamakawa, Satoko; Seo, Jinsoo; Rueda, Richard; Phan, Trongha X; Yamakawa, Hidekuni; Pao, Ping-Chieh; Stott, Ryan T; Gjoneska, Elizabeta; Nott, Alexi; Cho, Sukhee; Kellis, Manolis; Tsai, Li-Huei.

Cell ; 161(7): 1592-605, 2015 Jun 18.

Artigo em Inglês | MEDLINE | ID: mdl-26052046

2.

Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity.

Sakai, Mashito; Troutman, Ty D; Seidman, Jason S; Ouyang, Zhengyu; Spann, Nathanael J; Abe, Yohei; Ego, Kaori M; Bruni, Cassi M; Deng, Zihou; Schlachetzki, Johannes C M; Nott, Alexi; Bennett, Hunter; Chang, Jonathan; Vu, BaoChau T; Pasillas, Martina P; Link, Verena M; Texari, Lorane; Heinz, Sven; Thompson, Bonne M; McDonald, Jeffrey G; Geissmann, Frederic; Glass, Christopher K.

Immunity ; 51(4): 655-670.e8, 2019 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-31587991

3.

Somatic mosaicism reveals clonal distributions of neocortical development.

Breuss, Martin W; Yang, Xiaoxu; Schlachetzki, Johannes C M; Antaki, Danny; Lana, Addison J; Xu, Xin; Chung, Changuk; Chai, Guoliang; Stanley, Valentina; Song, Qiong; Newmeyer, Traci F; Nguyen, An; O'Brien, Sydney; Hoeksema, Marten A; Cao, Beibei; Nott, Alexi; McEvoy-Venneri, Jennifer; Pasillas, Martina P; Barton, Scott T; Copeland, Brett R; Nahas, Shareef; Van Der Kraan, Lucitia; Ding, Yan; Glass, Christopher K; Gleeson, Joseph G.

Nature ; 604(7907): 689-696, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35444276

4.

Artificial intelligence for neurodegenerative experimental models.

Marzi, Sarah J; Schilder, Brian M; Nott, Alexi; Frigerio, Carlo Sala; Willaime-Morawek, Sandrine; Bucholc, Magda; Hanger, Diane P; James, Charlotte; Lewis, Patrick A; Lourida, Ilianna; Noble, Wendy; Rodriguez-Algarra, Francisco; Sharif, Jalil-Ahmad; Tsalenchuk, Maria; Winchester, Laura M; Yaman, Ümran; Yao, Zhi; Ranson, Janice M; Llewellyn, David J.

Alzheimers Dement ; 19(12): 5970-5987, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37768001

5.

Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.

Morshed, Nader; Ralvenius, William T; Nott, Alexi; Watson, L Ashley; Rodriguez, Felicia H; Akay, Leyla A; Joughin, Brian A; Pao, Ping-Chieh; Penney, Jay; LaRocque, Lauren; Mastroeni, Diego; Tsai, Li-Huei; White, Forest M.

Mol Syst Biol ; 16(12): e9819, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33289969

6.

Immune memory in the brain.

Nott, Alexi; Glass, Christopher K.

Nature ; 556(7701): 312-313, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29662132

7.

S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration.

Seneviratne, Uthpala; Nott, Alexi; Bhat, Vadiraja B; Ravindra, Kodihalli C; Wishnok, John S; Tsai, Li-Huei; Tannenbaum, Steven R.

Proc Natl Acad Sci U S A ; 113(15): 4152-7, 2016 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-27035958

8.

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.

Nott, Alexi; Nitarska, Justyna; Veenvliet, Jesse V; Schacke, Stephan; Derijck, Alwin A H A; Sirko, Piotr; Muchardt, Christian; Pasterkamp, R Jeroen; Smidt, Marten P; Riccio, Antonella.

Proc Natl Acad Sci U S A ; 110(8): 3113-8, 2013 Feb 19.

Artigo em Inglês | MEDLINE | ID: mdl-23359715

9.

S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons.

Nott, Alexi; Watson, P Marc; Robinson, James D; Crepaldi, Luca; Riccio, Antonella.

Nature ; 455(7211): 411-5, 2008 Sep 18.

Artigo em Inglês | MEDLINE | ID: mdl-18754010

10.

Genetic insights into immune mechanisms of Alzheimer's and Parkinson's disease.

Nott, Alexi; Holtman, Inge R.

Front Immunol ; 14: 1168539, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37359515

11.

Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome.

Yildirim, Murat; Delepine, Chloe; Feldman, Danielle; Pham, Vincent A; Chou, Stephanie; Ip, Jacque; Nott, Alexi; Tsai, Li-Huei; Ming, Guo-Li; So, Peter T C; Sur, Mriganka.

Elife ; 112022 07 29.

Artigo em Inglês | MEDLINE | ID: mdl-35904330

12.

Nuclei isolation of multiple brain cell types for omics interrogation.

Nott, Alexi; Schlachetzki, Johannes C M; Fixsen, Bethany R; Glass, Christopher K.

Nat Protoc ; 16(3): 1629-1646, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33495627

13.

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease.

Pao, Ping-Chieh; Patnaik, Debasis; Watson, L Ashley; Gao, Fan; Pan, Ling; Wang, Jun; Adaikkan, Chinnakkaruppan; Penney, Jay; Cam, Hugh P; Huang, Wen-Chin; Pantano, Lorena; Lee, Audrey; Nott, Alexi; Phan, Trongha X; Gjoneska, Elizabeta; Elmsaouri, Sara; Haggarty, Stephen J; Tsai, Li-Huei.

Nat Commun ; 11(1): 2484, 2020 05 18.

Artigo em Inglês | MEDLINE | ID: mdl-32424276

14.

Brain cell type-specific enhancer-promoter interactome maps and disease-risk association.

Nott, Alexi; Holtman, Inge R; Coufal, Nicole G; Schlachetzki, Johannes C M; Yu, Miao; Hu, Rong; Han, Claudia Z; Pena, Monique; Xiao, Jiayang; Wu, Yin; Keulen, Zahara; Pasillas, Martina P; O'Connor, Carolyn; Nickl, Christian K; Schafer, Simon T; Shen, Zeyang; Rissman, Robert A; Brewer, James B; Gosselin, David; Gonda, David D; Levy, Michael L; Rosenfeld, Michael G; McVicker, Graham; Gage, Fred H; Ren, Bing; Glass, Christopher K.

Science ; 366(6469): 1134-1139, 2019 11 29.

Artigo em Inglês | MEDLINE | ID: mdl-31727856

15.

Dorsal hippocampal alpha7 and alpha4beta2 nicotinic receptors and memory.

Nott, Alexi; Levin, Edward D.

Brain Res ; 1081(1): 72-8, 2006 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-16556437

16.

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling.

Durak, Omer; Gao, Fan; Kaeser-Woo, Yea Jin; Rueda, Richard; Martorell, Anthony J; Nott, Alexi; Liu, Carol Y; Watson, L Ashley; Tsai, Li-Huei.

Nat Neurosci ; 19(11): 1477-1488, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27694995

17.

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

Nitarska, Justyna; Smith, Jacob G; Sherlock, William T; Hillege, Michele M G; Nott, Alexi; Barshop, William D; Vashisht, Ajay A; Wohlschlegel, James A; Mitter, Richard; Riccio, Antonella.

Cell Rep ; 17(6): 1683-1698, 2016 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-27806305

18.

Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.

Nott, Alexi; Cheng, Jemmie; Gao, Fan; Lin, Yuan-Ta; Gjoneska, Elizabeta; Ko, Tak; Minhas, Paras; Zamudio, Alicia Viridiana; Meng, Jia; Zhang, Feiran; Jin, Peng; Tsai, Li-Huei.

Nat Neurosci ; 19(11): 1497-1505, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27428650

19.

HDAC2 expression in parvalbumin interneurons regulates synaptic plasticity in the mouse visual cortex.

Nott, Alexi; Cho, Sukhee; Seo, Jinsoo; Tsai, Li-Huei.

Neuroepigenetics ; 1: 34-40, 2015 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-25705589

20.

Nitric oxide-mediated epigenetic mechanisms in developing neurons.

Nott, Alexi; Riccio, Antonella.

Cell Cycle ; 8(5): 725-30, 2009 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-19221483

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