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1.
J Phys Condens Matter ; 23(16): 164207, 2011 Apr 27.
Artigo em Inglês | MEDLINE | ID: mdl-21471612

RESUMO

We present transverse field muon spin rotation/relaxation measurements on single crystals of the spin-1/2 kagome antiferromagnet Herbertsmithite. We find that the spins are more easily polarized when the field is perpendicular to the kagome plane. We demonstrate that the difference in magnetization between the different directions cannot be accounted for by Dzyaloshinskii-Moriya-type interactions alone and that anisotropic axial interaction is present.

2.
Pharmacol Biochem Behav ; 97(4): 632-9, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21108959

RESUMO

Rats traversing a straight alley once a day for delivery of a single i.v. injection of cocaine develop over trials an ambivalence about entering the goal box. This ambivalence is characterized by the increasing occurrence of "retreat behaviors" where animals leave the start box and run quickly to the goal box, but then stop at the entry point and "retreat" back toward the start box. This unique pattern of retreat behavior has been shown to reflect a form of "approach-avoidance conflict" that stems from the animals' concurrent positive (cocaine reward) and negative (cocaine-induced anxiety) associations with the goal box. Cocaine blocks reuptake of the serotonergic (5-HT) transporter and serotonin has been implicated in the modulation of anxiety. It was therefore of interest to determine whether inactivation of the serotonergic cell bodies residing in the dorsal raphé nucleus (DRN) and projecting to brain areas critical for the modulation of anxiety, would alter the anxiogenic state exhibited by rats running an alley for single daily i.v. injections of 1.0mg/kg cocaine. Reversible inactivation of the DRN was accomplished by intracranial application of a mixed solution of the GABA agonists baclofen and muscimol. While DRN inactivation had no impact on the subjects' motivation to initiate responding (i.e., latencies to leave the start box were unaffected) it reliably reduced the frequency of approach-avoidance retreat behaviors (conflict behavior). These data suggest that inactivation of the dorsal raphé reduces the conflict/anxiety otherwise present in experienced cocaine-seeking animals.


Assuntos
Ansiedade/fisiopatologia , Cocaína/administração & dosagem , Motivação , Núcleos da Rafe/fisiologia , Animais , Comportamento Animal , Injeções Intravenosas , Masculino , Núcleos da Rafe/efeitos dos fármacos , Ratos , Ratos Sprague-Dawley
3.
Phys Rev Lett ; 94(23): 237202, 2005 Jun 17.
Artigo em Inglês | MEDLINE | ID: mdl-16090499

RESUMO

We investigated the nature of the freezing in the geometrically frustrated Heisenberg spin glass Y2(Mo2)O(7) by measuring the temperature dependence of the static internal magnetic field distribution above the spin-glass temperature, Tg, using the muon spin relaxation technique. The evolution of the field distribution cannot be explained by changes in the spin susceptibility alone and suggests a lattice deformation. This possibility is addressed by numerical simulations of the Heisenberg Hamiltonian with magnetoelastic coupling at T > 0.

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