Detalhe da pesquisa
1.
A Photoredox/Sulfide Dual Catalysis System That Uses Sulfide Radical Cations to Promote Alkene Chlorotrifluoromethylation.
Chem Pharm Bull (Tokyo)
; 71(9): 695-700, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37661375
2.
Essential structure of orexin 1 receptor antagonist YNT-707, part III: Role of the 14-hydroxy and the 3-methoxy groups in antagonistic activity toward the orexin 1 receptor in YNT-707 derivatives lacking the 4,5-epoxy ring.
Bioorg Med Chem
; 27(8): 1747-1758, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30871861
3.
Essential structure of orexin 1 receptor antagonist YNT-707, Part II: Drastic effect of the 14-hydroxy group on the orexin 1 receptor antagonistic activity.
Bioorg Med Chem Lett
; 28(4): 774-777, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29338909
4.
Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4,5-epoxy ring for binding with orexin 1 receptor.
Bioorg Med Chem Lett
; 27(17): 4176-4179, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28739044
5.
Synthesis of N-(acyloxy)-N-alkynylamides via generation of "C2" from hypervalent alkynyliodane and a weak base.
Chem Commun (Camb)
; 59(53): 8274-8277, 2023 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37317781
6.
Unexpected Rearrangement Reactions of the 14-Aminonaltrexone Skeleton.
Org Lett
; 25(19): 3407-3411, 2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37154730
7.
Design and Synthesis of Potent and Highly Selective Orexin 1 Receptor Antagonists with a Morphinan Skeleton and Their Pharmacologies.
J Med Chem
; 60(3): 1018-1040, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28051300