RESUMO
Hydrogel-based wound dressings are becoming increasingly important for wound healing. Bacterial cellulose (BC) has been commonly used as wound dressings due to its good in vitro and in vivo biocompatibility. However, pure BC does not possess antibacterial properties. In this regard, polycation gel was grafted onto the BC using a surface-initiated activator regenerated by electron transfer atom transfer radical polymerization (SI-ARGET ATRP) with subsequent quaternization for antibacterial wound dressing. Dimethylethyl methacrylate (DMAEMA) was successfully polymerized on the BC surface which was confirmed by Fourier transform infrared spectroscopy and elemental analysis. The morphology structure, specific surface area, pore size, and mechanical properties were also characterized. The quaternized PDMAEMA grafted on the BC endowed it with excellent antibacterial activity against E. coli (Gram-negative) and S. aureus (Gram-positive) with a killing rate of 89.2 % and 93.4 %, respectively. The number of cells was significantly reduced on QPD/BC hydrogel, demonstrating its good anti-adhesion ability. In vitro cellular evaluation revealed that the antibacterial wound dressing exhibited good biocompatibility. Overall, this study provides a feasible method to develop antibacterial and anti-cell adhesive hydrogel, which has a promising potential for wound healing.
Assuntos
Antibacterianos , Bandagens , Celulose , Escherichia coli , Polieletrólitos , Staphylococcus aureus , Cicatrização , Celulose/química , Celulose/farmacologia , Antibacterianos/farmacologia , Antibacterianos/química , Polieletrólitos/química , Polieletrólitos/farmacologia , Escherichia coli/efeitos dos fármacos , Staphylococcus aureus/efeitos dos fármacos , Cicatrização/efeitos dos fármacos , Poliaminas/química , Poliaminas/farmacologia , Hidrogéis/química , Hidrogéis/farmacologia , Animais , Metacrilatos/química , Camundongos , Testes de Sensibilidade Microbiana , Humanos , NylonsRESUMO
Solar-driven interfacial evaporation technology has attracted significant attention for water purification. However, design and fabrication of solar-driven evaporator with cost-effective, excellent capability and large-scale production remains challenging. In this study, inspired by plant transpiration, a tri-layered hierarchical nanofibrous photothermal membrane (HNPM) with a unidirectional water transport effect was designed and prepared via electrospinning for efficient solar-driven interfacial evaporation. The synergistic effect of the hierarchical hydrophilic-hydrophobic structure and the self-pumping effect endowed the HNPM with unidirectional water transport properties. The HNPM could unidirectionally drive water from the hydrophobic layer to the hydrophilic layer within 2.5 s and prevent reverse water penetration. With this unique property, the HNPM was coupled with a water supply component and thermal insulator to assemble a self-floating evaporator for water desalination. Under 1 sun illumination, the water evaporation rates of the designed evaporator with HNPM in pure water and dyed wastewater reached 1.44 and 1.78 kg·m-2·h-1, respectively. The evaporator could achieve evaporation of 11.04 kg·m-2 in 10 h under outdoor solar conditions. Moreover, the tri-layered HNPM exhibited outstanding flexibility and recyclability. Our bionic hydrophobic-to-hydrophilic structure endowed the solar-driven evaporator with capillary wicking and transpiration effects, which provides a rational design and optimization for efficient solar-driven applications.
RESUMO
Self-healing hydrogel products have attracted a great deal of interest in wound healing due to their ability to repair their own structural damage. Herein, an all-natural self-healing hydrogel based on methacrylated chitosan (CSMA) and dialdehyde bacterial cellulose (DABC) is developed. MA is used to modify CS and obtain water-soluble biomaterial-based CSMA with photo crosslinking effects. BC is modified through a simple oxidation method to gain dialdehyde on the polymer chain. The success of the modification is confirmed via FTIR. Hydrogels are formed within 11 min through the establishment of a Schiff base between the amino of CSMA and the aldehyde of DABC. A dynamically reversible Schiff base bond endows hydrogel with good self-healing properties through macroscopic and microscopic observations. We observe the uniform and porous structure in the hydrogel using SEM images, and DABC nanofibers are found to be well distributed in the hydrogel. The compressive strength of the hydrogel is more than 20 kPa and the swelling rate sees over a 10-fold increase. In addition, the CSMA/DABC hydrogel has good cytocompatibility, with cell viability exceeding 90%. These results indicate that the all-natural self-healable CSMA/DABC hydrogel demonstrates strong application potential in wound healing and tissue repair.
RESUMO
Cationic modification of cotton fabric was an effective way to improve the inkjet printing performance with reactive dye ink. However, there were few research studies that focused on the effect of the cationic agent structure, especially the alkyl chain length of the quaternary ammonium salt (QAS) cationic modifier, on the K/S value, dye fixation, and diffusion of inkjet-printed cotton fabric. In our work, different alkyl chain lengths of QAS were synthesized, and the inkjet printing performance of cationic cotton fabrics treated with different QASs was investigated. Compared with untreated cotton fabric, the K/S value and dye fixation of cationic cotton fabric treated with different QASs improved by 10.7 to 69.3% and 16.9 to 27.7%, respectively. With the increase in alkyl chain length of QAS, the interaction force between anionic reactive dyes and cationic QAS gradually increased mainly due to the fact that more N-positive ions on the quaternary ammonium group were exposed under the action of steric hindrance of alkyl chain length through the XPS spectrum. The electrostatic attraction between cationic cotton and reactive dye contributed to the diffusion of reactive dye into the fiber interior and enhanced the reaction probability of nucleophilic substitution reaction between monochlorotriazine reactive dye and the hydroxyl group of cotton fabric. The antibacterial result of the inkjet-printed cotton fabric indicated that when the alkyl chain length of QAS was higher than 8, the cationic cotton fabric obtained good antibacterial property.
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The emerging intelligent piezoresistive yarn/textile-based sensors are of paramount importance for skin-interface electronics, owing to their unparalleled features including softness, breathability, and easy integration with functional devices. However, employing a facile way to fabricate 1D sensing yarns with mechanical robustness, multi-functional integration, and comfortability is still demanded for satisfying the practical applications. Herein, a facile one-step synchronous conjugated electrospinning and electrospraying technique is innovatively employed to continuously construct an Ag NW-embedded polyurethane (PU) nanofiber sensing yarn (AENSY) with hierarchical architecture. This 1D AENSY with weavability and stretchability can be woven into AENSY textile-based sensors integrated with functions of strain and pressure sensing. In this embedded multi-scale architecture, Ag NWs are evenly embedded and locked in the oriented and twisted PU nanofiber (PUNF) scaffold, forming the hierarchical mechanical sensing layer on the surface of the AENSY with favorable stability. Meanwhile, the presence of the elastic PUNFs enhances porosity, elasticity, and considerable deformation space, which in turn endow the AENSY textile-based sensor with a gauge factor (GF) up to 1010, a pressure sensitivity up to 16.7 N-1, high stretchability up to 160%, and high stability under long-term cycles. In addition, the AENSY textile-based sensor exhibits light weight and the unique advantage of skin-friendliness with the human body, which can be directly and conformally attached to the curved human skin to monitor the various human movements. Furthermore, the weavable AENSYs can be integrated into smart textiles with sensing arrays, which are capable for spatial pressure and strain mapping. Thus, the continuous one-step developing process and the stable embedded-twisted fiber structure provide a promising strategy to develop innovative smart yarns and textiles for personalized healthcare and human-machine interfaces.
RESUMO
Antibacterial textiles, which effectively inhibit bacterial breeding and resist pathogenic diseases, have wide applications in medicine, hygiene, and related fields. However, traditional antibacterial textiles exhibit significant limitations, such as poor antibacterial durability and contamination during preparation. In this work, nanofiber yarn loaded with a high-efficiency antibacterial agent was prepared using electrospinning technology. Polyethyleneimine (PEI) was introduced as a solubilizing material to functionalize graphene oxide (GO) to form GO-PEI composites. A facile microwave heating method was used to synthesize GO-PEI and silver nanoparticles (AgNPs). A multi-needle conjugated electrospinning device was used to blend the nanofibers with the GO-PEI-Ag composite to form a nanofiber core-spun yarn. The antibacterial agent was firmly fixed on the fiber to prevent easy removal. A uniformly oriented yarn structure and internal morphology were observed, and the antibacterial activity of the fabric was measured. The antibacterial rate of the fabric was over 99.99%for both Escherichia coli and Staphylococcus aureus. After ten washes, the antibacterial rate remained above 99.99%. Thus, nanofiber fabric from electrospinning displays high antibacterial activity and excellent durability, thereby providing a feasible methodology for future production of antibacterial textiles.
Assuntos
Nanopartículas Metálicas , Nanocompostos , Nanofibras , Antibacterianos/farmacologia , Grafite , Prata/farmacologia , TêxteisRESUMO
It is well known that preparation method of hydrogels has a significant effect on their properties. In this paper, freeze-thawing and anneal-swelling were applied to prepare poly(vinyl alcohol)/polyacrylamide (PVA/PAM) double-network hydrogels with covalently and physically cross-linked networks. The properties of these hydrogels were investigated and compared to control hydrogels. Results indicated that hydrogels fabricated by freeze-thawing show larger pores size and higher swelling capacity than those made by anneal-swelling and control hydrogels. Hydrogels prepared by anneal-swelling exhibit higher mechanical strength, energy dissipation, fracture energy, gel fraction and crystallinity than those made by freeze-thawing and control hydrogels. Physical cross-linking plays a key role in formation of physical-chemical double-network. The toughening mechanism of double-network hydrogel is related to their chain-fracture behavior and elasticity. The results also indicated that appropriate methods can endow hydrogels with specific microstructures and properties which would broaden current hydrogels research and applications in biomedical fields.