Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.

Zhang, Lei; Li, Ziyi; Skrzypczynska, Katarzyna M; Fang, Qiao; Zhang, Wei; O'Brien, Sarah A; He, Yao; Wang, Lynn; Zhang, Qiming; Kim, Aeryon; Gao, Ranran; Orf, Jessica; Wang, Tao; Sawant, Deepali; Kang, Jiajinlong; Bhatt, Dev; Lu, Daniel; Li, Chi-Ming; Rapaport, Aaron S; Perez, Kristy; Ye, Yingjiang; Wang, Shan; Hu, Xueda; Ren, Xianwen; Ouyang, Wenjun; Shen, Zhanlong; Egen, Jackson G; Zhang, Zemin; Yu, Xin.

Cell ; 181(2): 442-459.e29, 2020 04 16.

Artigo em Inglês | MEDLINE | ID: mdl-32302573

2.

Regulation and functions of the IL-10 family of cytokines in inflammation and disease.

Ouyang, Wenjun; Rutz, Sascha; Crellin, Natasha K; Valdez, Patricia A; Hymowitz, Sarah G.

Annu Rev Immunol ; 29: 71-109, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21166540

3.

Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing.

Zheng, Chunhong; Zheng, Liangtao; Yoo, Jae-Kwang; Guo, Huahu; Zhang, Yuanyuan; Guo, Xinyi; Kang, Boxi; Hu, Ruozhen; Huang, Julie Y; Zhang, Qiming; Liu, Zhouzerui; Dong, Minghui; Hu, Xueda; Ouyang, Wenjun; Peng, Jirun; Zhang, Zemin.

Cell ; 169(7): 1342-1356.e16, 2017 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-28622514

4.

Mice deficient in NRROS show abnormal microglial development and neurological disorders.

Wong, Kit; Noubade, Rajkumar; Manzanillo, Paolo; Ota, Naruhisa; Foreman, Oded; Hackney, Jason A; Friedman, Brad A; Pappu, Rajita; Scearce-Levie, Kimberly; Ouyang, Wenjun.

Nat Immunol ; 18(6): 633-641, 2017 06.

Artigo em Inglês | MEDLINE | ID: mdl-28459434

5.

Human Anti-tumor Immunity: Insights from Immunotherapy Clinical Trials.

Egen, Jackson G; Ouyang, Wenjun; Wu, Lawren C.

Immunity ; 52(1): 36-54, 2020 01 14.

Artigo em Inglês | MEDLINE | ID: mdl-31940272

6.

IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation.

Ouyang, Wenjun; O'Garra, Anne.

Immunity ; 50(4): 871-891, 2019 04 16.

Artigo em Inglês | MEDLINE | ID: mdl-30995504

7.

Signaling via the IL-20 receptor inhibits cutaneous production of IL-1ß and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus.

Myles, Ian A; Fontecilla, Natalia M; Valdez, Patricia A; Vithayathil, Paul J; Naik, Shruti; Belkaid, Yasmine; Ouyang, Wenjun; Datta, Sandip K.

Nat Immunol ; 14(8): 804-11, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23793061

8.

The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.

Wang, Chenhui; Wu, Ling; Bulek, Katarzyna; Martin, Bradley N; Zepp, Jarod A; Kang, Zizhen; Liu, Caini; Herjan, Tomasz; Misra, Saurav; Carman, Julie A; Gao, Ji; Dongre, Ashok; Han, Shujie; Bunting, Kevin D; Ko, Jennifer S; Xiao, Hui; Kuchroo, Vijay K; Ouyang, Wenjun; Li, Xiaoxia.

Nat Immunol ; 14(1): 72-81, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23202271

9.

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens.

Satpathy, Ansuman T; Briseño, Carlos G; Lee, Jacob S; Ng, Dennis; Manieri, Nicholas A; Kc, Wumesh; Wu, Xiaodi; Thomas, Stephanie R; Lee, Wan-Ling; Turkoz, Mustafa; McDonald, Keely G; Meredith, Matthew M; Song, Christina; Guidos, Cynthia J; Newberry, Rodney D; Ouyang, Wenjun; Murphy, Theresa L; Stappenbeck, Thaddeus S; Gommerman, Jennifer L; Nussenzweig, Michel C; Colonna, Marco; Kopan, Raphael; Murphy, Kenneth M.

Nat Immunol ; 14(9): 937-48, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-23913046

10.

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity.

Canon, Jude; Rex, Karen; Saiki, Anne Y; Mohr, Christopher; Cooke, Keegan; Bagal, Dhanashri; Gaida, Kevin; Holt, Tyler; Knutson, Charles G; Koppada, Neelima; Lanman, Brian A; Werner, Jonathan; Rapaport, Aaron S; San Miguel, Tisha; Ortiz, Roberto; Osgood, Tao; Sun, Ji-Rong; Zhu, Xiaochun; McCarter, John D; Volak, Laurie P; Houk, Brett E; Fakih, Marwan G; O'Neil, Bert H; Price, Timothy J; Falchook, Gerald S; Desai, Jayesh; Kuo, James; Govindan, Ramaswamy; Hong, David S; Ouyang, Wenjun; Henary, Haby; Arvedson, Tara; Cee, Victor J; Lipford, J Russell.

Nature ; 575(7781): 217-223, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31666701

11.

Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection.

Muñoz, Melba; Eidenschenk, Celine; Ota, Naruhisa; Wong, Kit; Lohmann, Uwe; Kühl, Anja A; Wang, Xiaoting; Manzanillo, Paolo; Li, Yun; Rutz, Sascha; Zheng, Yan; Diehl, Lauri; Kayagaki, Nobuhiko; van Lookeren-Campagne, Menno; Liesenfeld, Oliver; Heimesaat, Markus; Ouyang, Wenjun.

Immunity ; 42(2): 321-331, 2015 Feb 17.

Artigo em Inglês | MEDLINE | ID: mdl-25680273

12.

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer.

Zhang, Lei; Yu, Xin; Zheng, Liangtao; Zhang, Yuanyuan; Li, Yansen; Fang, Qiao; Gao, Ranran; Kang, Boxi; Zhang, Qiming; Huang, Julie Y; Konno, Hiroyasu; Guo, Xinyi; Ye, Yingjiang; Gao, Songyuan; Wang, Shan; Hu, Xueda; Ren, Xianwen; Shen, Zhanlong; Ouyang, Wenjun; Zhang, Zemin.

Nature ; 564(7735): 268-272, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30479382

13.

The Itch to degrade ROR-Î³t.

Rutz, Sascha; Ouyang, Wenjun.

Nat Immunol ; 17(8): 898-900, 2016 07 19.

Artigo em Inglês | MEDLINE | ID: mdl-27434002

14.

IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium.

Ota, Naruhisa; Wong, Kit; Valdez, Patricia A; Zheng, Yan; Crellin, Natasha K; Diehl, Lauri; Ouyang, Wenjun.

Nat Immunol ; 12(10): 941-8, 2011 Aug 28.

Artigo em Inglês | MEDLINE | ID: mdl-21874025

15.

Transcription factor c-Maf mediates the TGF-ß-dependent suppression of IL-22 production in T(H)17 cells.

Rutz, Sascha; Noubade, Rajkumar; Eidenschenk, Céline; Ota, Naruhisa; Zeng, Wenwen; Zheng, Yan; Hackney, Jason; Ding, Jiabing; Singh, Harinder; Ouyang, Wenjun.

Nat Immunol ; 12(12): 1238-45, 2011 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-22001828

16.

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.

Ramirez-Carrozzi, Vladimir; Sambandam, Arivazhagan; Luis, Elizabeth; Lin, Zhongua; Jeet, Surinder; Lesch, Justin; Hackney, Jason; Kim, Janice; Zhou, Meijuan; Lai, Joyce; Modrusan, Zora; Sai, Tao; Lee, Wyne; Xu, Min; Caplazi, Patrick; Diehl, Lauri; de Voss, Jason; Balazs, Mercedesz; Gonzalez, Lino; Singh, Harinder; Ouyang, Wenjun; Pappu, Rajita.

Nat Immunol ; 12(12): 1159-66, 2011 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-21993848

17.

Th17 cells at the crossroads of autoimmunity, inflammation, and atherosclerosis.

van Bruggen, Nicholas; Ouyang, Wenjun.

Immunity ; 40(1): 10-2, 2014 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-24439264

18.

The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria.

Behnsen, Judith; Jellbauer, Stefan; Wong, Christina P; Edwards, Robert A; George, Michael D; Ouyang, Wenjun; Raffatellu, Manuela.

Immunity ; 40(2): 262-73, 2014 Feb 20.

Artigo em Inglês | MEDLINE | ID: mdl-24508234

19.

Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria.

Basu, Rajatava; O'Quinn, Darrell B; Silberger, Daniel J; Schoeb, Trenton R; Fouser, Lynette; Ouyang, Wenjun; Hatton, Robin D; Weaver, Casey T.

Immunity ; 37(6): 1061-75, 2012 Dec 14.

Artigo em Inglês | MEDLINE | ID: mdl-23200827

20.

Cutting Edge: IL-17B Uses IL-17RA and IL-17RB to Induce Type 2 Inflammation from Human Lymphocytes.

Ramirez-Carrozzi, Vladimir; Ota, Naruhisa; Sambandam, Arivazhagan; Wong, Kit; Hackney, Jason; Martinez-Martin, Nadia; Ouyang, Wenjun; Pappu, Rajita.

J Immunol ; 202(7): 1935-1941, 2019 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-30770417

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