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BACKGROUND: Despite regulations mandating follow-up laboratory testing for living kidney donors, less than half of transplant centers are in compliance. We sought to understand barriers to follow-up testing from the donors' perspective. METHODS: We surveyed our center's living kidney donors. Binary logistic regression was used to assess factors associated with follow-up testing completion. RESULTS: Of 185 living kidney donors, 110 (59.4%) participated. Among them, 82 (74.5%) completed 6-month laboratory testing, 76 (69.1%) completed 12-month testing, 68 (61.8%) completed both, and 21 (19.0%) completed neither. Six-month testing completion was strongly associated with 12-month testing completion (OR 9.74, 95%CI: 2.23-42.50; p = .002). Those who disagreed with the statements, "Getting labs checked wasn't a priority for me," (OR for completing 6-month testing: 15.05, 95%CI: 3.70-61.18; p < .001; OR for completing 12-month testing: 5.85, 95%CI: 1.94-17.63; p = .002); and, "I forgot to get labs drawn [until I was reminded]" (OR for completing 6-month testing: 6.93, 95%CI: 1.59-30.08; p = .01; OR for completing 12-month testing: 6.55, 95%CI: 1.98-21.63; p = .002) were more likely to complete testing. CONCLUSIONS: To our knowledge, this is the only study providing perspective on donor insights regarding the need for follow-up testing post donation. Interventions to influence living donor attitudes toward follow-up testing may improve follow-up.
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Transplante de Rim , Doadores Vivos , Seguimentos , Humanos , Modelos Logísticos , Inquéritos e QuestionáriosRESUMO
BACKGROUND: Improved survival among people with human immunodeficiency virus (HIV) (PWH) has led to increased organ failure, necessitating transplantation. In 2013, the HIV Organ Policy Equity (HOPE) Act was passed, allowing PWH to donate organs to other PWH. No study has assessed organ quality and quantity among a national pool of PWH. METHODS: CFAR Network of Integrated Clinical Systems (CNICS), a multicenter study capturing data on PWH, was used to identify 6504 deaths from 1999 to 2018. Exclusions included cause of death, chronic kidney disease, fibrosis-4 score ≥ 3.25, and opportunistic infection at the time of death. Donor quality was defined by HIV viremia and the kidney donor profile index (KDPI). The CDC Wonder database, which contains national death data, permitted the estimation of deaths among PWH nationally from 1999 to 2018. Assuming CNICS was representative of PWH nationally, percentages of potential donors were applied to the CDC Wonder cohort. RESULTS: Within CNICS, there were 3241 (65.9%) potential kidney donors and 3536 (71.9%) potential liver donors from 1999 to 2018. Based on viremia and KDPI, 821 were lower-risk kidney donors (16.7%) and 1206 (24.5%) were lower-risk liver donors. Within CDC Wonder, we identified 12 048 potential donors from 1999 to 2018. Extrapolating from CNICS to the national cohort suggested 396 kidney donors (792 kidneys) and 433 liver donors annually, with 100 kidney donors (200 kidneys) and 147 livers being lower-risk. CONCLUSION: A substantial number of PWH meet donation criteria, a valuable source of organs for PWH in need of transplants. Our estimates suggest there may be more available organs from PWH than current transplant numbers indicate.
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Soropositividade para HIV , Transplante de Rim , Obtenção de Tecidos e Órgãos , Humanos , Viremia , Doadores de Tecidos , Transplante de Rim/efeitos adversos , HIV , Sobrevivência de EnxertoRESUMO
Background: Measurement-based care (MBC) is an effective tool in the delivery of evidence-based practices (EBPs). MBC utilizes feedback loops to share information and drive changes throughout a learning healthcare system. Few studies have demonstrated this practice in team-based care for people with early psychosis. This paper describes the development of a personalized feedback report derived from routine assessments that is shared with clients and clinicians as part of a MBC process. Methods: We used a quasi pre-post comparison design with mixed methods to evaluate the implementation of a personalized feedback report at 5 early psychosis coordinated specialty care programs (CSC). We compared clients enrolled in CSC who did and did not receive a feedback report over the first 6 months of treatment. The sample included 204 clients: 146 who did not receive the feedback report and were enrolled over 2 years, and 58 who received the feedback report. A subset of 67 clients completed measures at both intake and 6-month follow-up, including 42 who received the report and 25 who did not. We compared the two groups with regard to self-reported symptoms, likelihood of completing treatment, and perception of shared decision making. We conducted qualitative interviews with 5 clients and 5 clinicians to identify the benefits and challenges associated with the personalized feedback report. Results: People who received a personalized feedback report reported significant improvements in shared decision-making and had greater improvements over time in their intent to attend future treatment sessions. They engaged in more sessions for Supported Employment and Education (SEE), case management, and peer support, and fewer medication visits over the first 6 months of treatment. Both groups showed significant improvement in symptoms and functioning. Results from the qualitative analysis indicated that the experience of receiving the reports was valuable and validating for both patients and clinicians. Conclusions: A personalized feedback report was integrated into standard of care for early psychosis programs. This process may improve shared decision-making, strengthen the likelihood to stay in treatment, and increase engagement in psychosocial interventions. We posit that this process facilitates strengths-focused discussions, enhances intrinsic motivation, and strengthens the therapeutic alliance.
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Objectives: Safety practices such as storing a firearm locked and unloaded are widely promoted although not universally applied. Educating patients about firearm safety practices is effective in increasing safe firearms storage behaviors; however, screening for safe firearm storage in practice remains low. The aim of this study was to evaluate whether our clinic population was at risk for firearm-related injuries and whether opportunities existed to study risk-mitigation interventions in future work. Methods: The study was conducted at a suburban, midwestern academic family medicine clinic. Patients filled out paper surveys about firearm ownership and willingness to discuss firearms safety with clinicians. Health care personnel filled out paper or electronic surveys about their comfort level in discussing firearm safety with patients. Data then were collated and analyzed. Results: We surveyed 160 patients (60% female, 80% White), and 40.6% of respondents reported living in a home with a firearm. Respondents who stored their firearm unsafely were more willing to discuss firearm safety than to change their storage behavior. Eighteen health care personnel responded to our health care personnel survey. Perceived barriers to asking about firearms included lack of time, knowledge, or educational materials. Having a screening policy was selected as the best opportunity for improvement. Conclusions: Firearm owners appear willing to discuss firearm safety with their clinician, potentially representing an opportunity to promote risk-reduction through approaches such as motivational interviewing. In a busy outpatient setting, automating the firearm screening process could lessen the burden on clinicians.
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Previous studies have shown that listening to preferred music during resistance and endurance exercises improves performance. However, it is unknown if these phenomena translate to short-duration explosive exercises. The purpose of this study was to investigate the influences of preferred and non-preferred music on countermovement jump (CMJ) performance, isometric mid-thigh pull (IMTP), and psychological responses to music during explosive movements. Physically active females (age 18-25) volunteered to take part in the study. In a counterbalanced, crossover design, participants completed three trials: (1) no music (NM), (2) non-preferred (NP), and (3) preferred (PV) music. Participants completed three maximal IMTP tests on a force-plate-equipped IMTP apparatus with an immovable bar. Attempts lasted 5 s and were separated by 3 min of rest. Furthermore, participants completed three single maximal CMJ attempts separated by 3 min of rest on force plates. All attempts were averaged for analysis. At the commencement of IMTP and CMJ testing, participants were asked to rate how motivated and psyched up they felt during the exercise portion using a visual analog scale. For isometric performance, listening to PM resulted in increased peak force (p = 0.039; d = 0.41) and rate of force development at 200 ms (p = 0.023; d = 0.91) compared with NP. For CMJ, there were no differences between conditions for jump height (p = 0.912; η2 = 0.007) or peak power during the propulsive phase (p = 0.460; η2 = 0.003). Levels of motivation were significantly higher with PM compared with NM (p < 0.001; d = 2.3) and NP (p = 0.001; d = 2.0). Feelings of being psyched up were significantly higher with PM compared with NM (p < 0.001; d = 4.2) and NP (p = 0.001; d = 2.8). Findings suggest that preferred music enhances isometric strength and increases motivation and feelings of being psyched up. Thus, PM may be used as an ergogenic aid during short-duration maximal-effort activities.
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OBJECTIVES/HYPOTHESIS: To evaluate muscle fatigue and participant pain in the upper back, cervical, and arm muscles associated with microlaryngeal surgery (MLS) in standardized favorable and unfavorable ergonomic positions. STUDY DESIGN: Individual randomized counterbalanced design. METHODS: Electromyographic sensors were placed on targeted muscles involved with performing MLS on 18 otolaryngology residents/fellows. Subjects were randomly counterbalanced in both favorable and unfavorable positions while completing simulated laryngeal microsurgical tasks. Participants reported their extent of muscle discomfort in targeted muscle regions on a standardized survey. RESULTS: Muscle fatigue and self-reported pain were reduced, and productivity was improved in the favorable position. In the lower trapezius, significantly less muscle activation (P = 0.025) and less pain (P < 0.05) were found while in the favorable position compared to the unfavorable position. CONCLUSION: This is the first study to demonstrate electromyographic evidence of decreased muscle activation and fatigue, in addition to self-reported pain with a more favorable microsurgical ergonomic position, which may help surgeons avoid musculoskeletal injuries.