Detalhe da pesquisa
1.
Targeting Trypanothione Metabolism in Trypanosomatids.
Molecules
; 29(10)2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38792079
2.
Miltefosine and Nifuratel Combination: A Promising Therapy for the Treatment of Leishmania donovani Visceral Leishmaniasis.
Int J Mol Sci
; 24(2)2023 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36675150
3.
Antileishmanial Effect of 1,5- and 1,8-Substituted Fused Naphthyridines.
Molecules
; 29(1)2023 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38202656
4.
Novel phenanthridine amide analogs as potential anti-leishmanial agents: In vitro and in silico insights.
Bioorg Chem
; 117: 105414, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34655843
5.
Screening Marine Natural Products for New Drug Leads against Trypanosomatids and Malaria.
Mar Drugs
; 18(4)2020 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32244488
6.
Antiparasitic effect of synthetic aromathecins on Leishmania infantum.
BMC Vet Res
; 15(1): 405, 2019 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31706354
7.
Polyamine Metabolism for Drug Intervention in Trypanosomatids.
Pathogens
; 13(1)2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38251386
8.
In Vitro and Ex Vivo Synergistic Effect of Pyrvinium Pamoate Combined with Miltefosine and Paromomycin against Leishmania.
Trop Med Infect Dis
; 9(2)2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38393119
9.
A pentapeptide signature motif plays a pivotal role in Leishmania DNA topoisomerase IB activity and camptothecin sensitivity.
Biochim Biophys Acta
; 1820(12): 2062-71, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23000572
10.
Further Investigations of Nitroheterocyclic Compounds as Potential Antikinetoplastid Drug Candidates.
Biomolecules
; 13(4)2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37189384
11.
Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.
Pharmaceuticals (Basel)
; 16(5)2023 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242440
12.
Indotecan (LMP400) and AM13-55: two novel indenoisoquinolines show potential for treating visceral leishmaniasis.
Antimicrob Agents Chemother
; 56(10): 5264-70, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22850521
13.
Axenic interspecies and intraclonal hybrid formation in Leishmania: Successful crossings between visceral and cutaneous strains.
PLoS Negl Trop Dis
; 16(2): e0010170, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35139072
14.
Design, synthesis and evaluation of novel ß-carboline ester analogues as potential anti-leishmanial agents.
J Biomol Struct Dyn
; 40(23): 12592-12607, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34488559
15.
Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase.
Parasitology
; 138(9): 1082-92, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21813028
16.
Reproduction in Trypanosomatids: Past and Present.
Biology (Basel)
; 10(6)2021 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34071741
17.
Ex Vivo Phenotypic Screening of Two Small Repurposing Drug Collections Identifies Nifuratel as a Potential New Treatment against Visceral and Cutaneous Leishmaniasis.
ACS Infect Dis
; 7(8): 2390-2401, 2021 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34114790
18.
Bioluminescent Imaging Identifies Thymus, As Overlooked Colonized Organ, in a Chronic Model of Leishmania donovani Mouse Visceral Leishmaniasis.
ACS Infect Dis
; 7(4): 871-883, 2021 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33739807
19.
Hybrid Quinolinyl Phosphonates as Heterocyclic Carboxylate Isosteres: Synthesis and Biological Evaluation against Topoisomerase 1B (TOP1B).
Pharmaceuticals (Basel)
; 14(8)2021 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34451880
20.
Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1.
Pharmaceutics
; 13(8)2021 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34452216