Detalhe da pesquisa
1.
Na+ controls hypoxic signalling by the mitochondrial respiratory chain.
Nature
; 586(7828): 287-291, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728214
2.
Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death.
FASEB J
; 33(8): 8961-8975, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31034781
3.
QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy.
Molecules
; 24(8)2019 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30999586
4.
Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.
Angew Chem Int Ed Engl
; 56(41): 12765-12769, 2017 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28861918
5.
Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4.
Antioxidants (Basel)
; 12(9)2023 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37760032
6.
Tweak/Fn14 system is involved in rhabdomyolysis-induced acute kidney injury.
Biomed Pharmacother
; 169: 115925, 2023 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38007933
7.
Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma.
Pharmaceutics
; 14(8)2022 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35893807
8.
Time-dependent dual effect of NLRP3 inflammasome in brain ischaemia.
Br J Pharmacol
; 179(7): 1395-1410, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34773639
9.
Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout.
J Med Chem
; 65(8): 6250-6260, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35403430
10.
Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer's Disease.
Pharmaceuticals (Basel)
; 14(9)2021 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34577561
11.
TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury.
Br J Pharmacol
; 178(17): 3395-3413, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33830504
12.
Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients.
Biomedicines
; 9(6)2021 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34070533
13.
Protective Role of Nrf2 in Renal Disease.
Antioxidants (Basel)
; 10(1)2020 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33396350
14.
Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux.
Antioxidants (Basel)
; 9(12)2020 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33353046
15.
Multiple Morphometric Assessment of Microglial Cells in Deafferented Spinal Trigeminal Nucleus.
Front Neuroanat
; 13: 103, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32038181
16.
Early toll-like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro-inflammatory phenotype in rodent and human brain ischaemia models.
Br J Pharmacol
; 176(15): 2764-2779, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31074003
17.
New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition.
J Med Chem
; 62(24): 11416-11422, 2019 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31724859
18.
Adverse effects of the renal accumulation of haem proteins. Novel therapeutic approaches. / Efectos adversos de la acumulación renal de hemoproteínas. Nuevas herramientas terapéuticas.
Nefrologia (Engl Ed)
; 38(1): 13-26, 2018.
Artigo
em Inglês, Espanhol
| MEDLINE | ID: mdl-28668175
19.
Targeting Nrf2 in Protection Against Renal Disease.
Curr Med Chem
; 24(33): 3583-3605, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28494744