Unusual case of massive hemorrhage of a gastric duplication cyst in a very advanced age.

PURPOSE: The objective of this study was to report an unusual case of gastric duplication in an 82-year-old female patient. MATERIALS AND METHODS: The patient was treated immediately by Billroth I partial gastrectomy due to massive hematemesis. The surgical specimen was histopathologically examined. RESULTS: The histopathologic report confirmed the operative diagnosis of a gastric duplication cyst. Gastric duplication cysts are rare congenital abnormalities occurring mainly in the pediatric population and rarely in adults. They account for 2% to 7% of all gastrointestinal duplications, having a male to female ratio of 2:1 (Agha et al., AJR Am J Roentgenol 137:406-407, 1981; Macpherson, Radiographics 13:1063-1080, 1993). CONCLUSIONS: Gastric duplication cysts present with a variety of symptoms and complications including hematemesis. The massive upper gastrointestinal hemorrhage in our octogenarian patient indicates that there is no age limit in clinical manifestations of this rather common in the pediatric population, congenital malformation of the stomach.

Acute painless monocular visual loss due to central retinal artery occlusion in a patient with Churg-Strauss vasculitis.

Ocular involvement in Churg-Strauss syndrome (CSS) is infrequent. We describe a case of a 50-year-old woman, with blood eosinophilia, involvement of the respiratory tract, skin, and peripheral nervous system, fulfilling the American College of Rheumatology criteria for CSS, who presented with left foot drop followed by left acute painless visual loss. Central retinal artery occlusion was diagnosed by fundoscopic findings (retinal whitening with a cherry-red spot). CSS was confirmed by sural nerve biopsy. Despite treatment with high-dose corticosteroids, cyclophosphamide, and anticoagulant therapy, visual acuity was not substantially improved. Acute blindness in CSS has been rarely described. Even more rarely, central retinal artery occlusion has been found to be the underlying cause of this infrequent clinical manifestation in CSS.

Blastic natural killer (NK)-cell lymphoma: report of an unusual CD4 negative case and review of the CD4 negative neoplasms with blastic features in the literature.

Blastic Natural Killer (NK)-cell lymphoma is a relatively new entity which has been recently included in the WHO classification. CD4 expression is observed in most cases of blastic NK-cell lymphomas and has been related with skin tropism. We report an unusual CD4 negative blastic NK-cell lymphoma with primary presentation in the skin, subsequent infiltration of the bone marrow and aggressive behavior. It is emphasized that extensive immunophenotyping and EBER RNA in situ hybridization are required in order to establish the diagnosis of blastic NK-cell lymphoma. We also present a review of the literature with respect to the CD4 negative NK-cell lymphomas with blastic morphological features.