Detalhe da pesquisa
1.
Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation.
Nat Immunol
; 18(10): 1104-1116, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28825701
2.
The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair.
Immunity
; 51(2): 241-257.e9, 2019 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31303399
3.
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF.
Immunity
; 47(2): 235-250.e4, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28813657
4.
Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis.
Immunity
; 55(11): 2209, 2022 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36351378
5.
Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis.
Immunity
; 47(1): 66-79.e5, 2017 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28723554
6.
WNT-modulating gene silencers as a gene therapy for osteoporosis, bone fracture, and critical-sized bone defects.
Mol Ther
; 31(2): 435-453, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36184851
7.
Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages.
Nat Immunol
; 12(7): 607-15, 2011 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21602809
8.
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
Nature
; 526(7571): 112-7, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26367794
9.
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes.
Nat Immunol
; 9(4): 378-87, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18345002
10.
'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages.
Nat Immunol
; 9(2): 186-93, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18084294
11.
Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.
Immunity
; 32(4): 518-30, 2010 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20362473
12.
Mechanisms involved in normal and pathological osteoclastogenesis.
Cell Mol Life Sci
; 75(14): 2519-2528, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29670999
13.
Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8.
J Immunol
; 196(11): 4452-4456, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27183582
14.
Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass.
Proc Natl Acad Sci U S A
; 112(51): 15654-9, 2015 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26644563
15.
Epigenetic regulation of bone cells.
Connect Tissue Res
; 58(1): 76-89, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27082893
16.
Intravenous Immunoglobulin (IVIG) Attenuates TNF-Induced Pathologic Bone Resorption and Suppresses Osteoclastogenesis by Inducing A20 Expression.
J Cell Physiol
; 231(2): 449-458, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26189496
17.
Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts.
Arthritis Rheum
; 65(4): 928-38, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23335080
18.
ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes.
J Immunol
; 188(7): 3447-57, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22368279
19.
New Horizons: Translational Aspects of Osteomorphs.
J Clin Endocrinol Metab
; 109(5): e1373-e1378, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38060842
20.
Origin of Osteoclasts: Osteoclast Precursor Cells.
J Bone Metab
; 30(2): 127-140, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37449346