Detalhe da pesquisa
1.
Misfolded SOD1 is not a primary component of sporadic ALS.
Acta Neuropathol
; 134(1): 97-111, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28247063
2.
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43.
Proc Natl Acad Sci U S A
; 110(8): E736-45, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382207
3.
Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis.
J Neurosci
; 33(11): 4657-71, 2013 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23486940
4.
Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.
J Biol Chem
; 288(35): 25266-25274, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23867462
5.
SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability.
Biochim Biophys Acta
; 1783(5): 904-11, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18339324
6.
Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.
Mol Cell Biol
; 26(20): 7397-408, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17015472
7.
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
Elife
; 82019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30747709
8.
ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.
Neuron
; 100(4): 816-830.e7, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30344044
9.
Mitochondrial fission and apoptosis: an ongoing trial.
Biochim Biophys Acta
; 1763(5-6): 522-30, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16762428
10.
Mechanisms of mitochondrial outer membrane permeabilization.
Novartis Found Symp
; 287: 170-6; discussion 176-82, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18074638
11.
Building the mitochondrial proteome.
Expert Rev Proteomics
; 2(4): 541-51, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16097887
12.
ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.
Neuron
; 106(2): 354, 2020 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32325059
13.
Mitochondrial Isolation and Purification from Mouse Spinal Cord.
Bio Protoc
; 3(21)2013 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27819013
14.
Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS.
Cell Metab
; 15(5): 778-86, 2012 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22560226
15.
SLP-2 negatively modulates mitochondrial sodium-calcium exchange.
Cell Calcium
; 47(1): 11-8, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19944461
16.
Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA.
PLoS One
; 3(9): e3257, 2008 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18806874
17.
hFis1, a novel component of the mammalian mitochondrial fission machinery.
J Biol Chem
; 278(38): 36373-9, 2003 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-12783892