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1.
Adv Skin Wound Care ; 36(1): 54-55, 2023 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-36537776

RESUMO

ABSTRACT: Up to 80% of individuals with an ostomy experience a peristomal skin complication, which can result in significant healthcare issues. All clinicians working with patients with stomas need to be aware of the signs and symptoms of peristomal skin complications and basic strategies to address the most common cause of skin complications: leakage of stool or other effluent onto the skin. Use of an evidence-based, standardized instrument to guide peristomal assessment and selection of appropriate interventions can improve patient outcomes and increase meaningful collaboration between all members of the healthcare team. This case study addresses dilemmas of care during a non-ostomy-related hospitalization.


Assuntos
Estomia , Dermatopatias , Estomas Cirúrgicos , Humanos , Estomia/efeitos adversos , Pele , Dermatopatias/complicações , Estomas Cirúrgicos/efeitos adversos , Higiene da Pele/efeitos adversos
2.
Br J Nurs ; 29(20): S32-S37, 2020 Nov 12.
Artigo em Inglês | MEDLINE | ID: mdl-33180613

RESUMO

The problem of itch occurring with chronic wounds has been recognised, but is often ignored in practice. This paper describes the process of how the 'theory of wound itch' was formulated from Levine's conservation model. Concepts and propositions from the conceptual model were used to develop the theory. The theory will provide a basis for nursing research and practice.


Assuntos
Pesquisa em Enfermagem , Prurido , Humanos , Teoria de Enfermagem
5.
JACC Adv ; 3(4)2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38770230

RESUMO

BACKGROUND: Understanding the clinical features of myocarditis in various age groups is required to identify age-specific disease patterns. OBJECTIVES: The objective of this study was to examine differences in sex distribution and clinical outcomes in patients with myocarditis of various ages. METHODS: Patients with acute or chronic myocarditis in 3 centers in Berlin, Germany from 2005 to 2021 and in the United States (National Inpatient Sample) from 2010 to 2019 were included. Age groups examined included "prepubescent" (below 11 years for females and below 13 years for males), adolescents (11 [female] or 13 [male] to 18 years), young adults (18-35 years), "middle-aged adults" (35-54 years), and older adults (age >54 years). In patients admitted to the hospital, hospital mortality, length of stay, and medical complication rates were examined. RESULTS: Overall, 6,023 cases in Berlin and 9,079 cases in the U.S. cohort were included. In both cohorts, there were differences in sex distribution among the 5 age categories, and differences in the distribution were most notable in adolescents (69.3% males vs 30.7% females) and in young adults (73.8% males vs 26.3% females). Prepubescent and older adults had the highest rates of in-hospital mortality, hospital length of stay, and medical complications. In the Berlin cohort, prepubescent patients had higher levels of leukocytes (P < 0.001), antistreptolysin antibody (P < 0.001), and NT-proBNP (P < 0.001) when compared to young adults. CONCLUSIONS: In this study, we found that sex differences in myocarditis and clinical features of myocarditis were age-dependent.

6.
Anim Cogn ; 16(1): 99-107, 2013 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22945433

RESUMO

To recognize that a picture is a representation of a real-life object is a cognitively demanding task. It requires an organism to mentally represent the concrete object (the picture) and abstract its relation to the item that it represents. This form of representational insight has been shown in a small number of mammal and bird species. However, it has not previously been studied in reptiles. This study examined picture-object recognition in the red-footed tortoise (Chelonoidis carbonaria). In Experiment 1, five red-footed tortoises were trained to distinguish between food and non-food objects using a two-alternative forced choice procedure. After reaching criterion, they were presented with test trials in which the real objects were replaced with color photographs of those objects. There was no difference in performance between training and test trials, suggesting that the tortoises did see some correspondence between the real object and its photographic representation. Experiment 2 examined the nature of this correspondence by presenting the tortoises with a choice between the real food object and a photograph of it. The findings revealed that the tortoises confused the photograph with the real-life object. This suggests that they process real items and photographic representations of these items in the same way and, in this context, do not exhibit representational insight.


Assuntos
Reconhecimento Psicológico , Percepção Visual , Animais , Comportamento de Escolha , Alimentos , Tartarugas
7.
Adv Skin Wound Care ; 26(7): 320-32; quiz 333-4, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23777882

RESUMO

OBJECTIVE: This study was designed to explore characteristics of chronic wounds that present with wound-related itch. BACKGROUND: Although wound-related itch is recognized clinically, little is known about the phenomenon. Recent scientific advances have enabled the study of itch physiology, yet the clinical problem is not well described in the literature. DESIGN: The study was observational, descriptive. METHOD: Persons (N = 200) with wounds being followed up at a hospital-affiliated wound care center were interviewed and assessed. Instruments included a health history tool, Paul-Pieper Itching Questionnaire, Bates-Jensen Wound Assessment Tool, and 10-g monofilament for assessment of sensation in the area of the wound. RESULTS: Participants were aged 21 to 98 years (mean, 66.82 [SD, 14.02] years); 56% of the participants were men, and 85% were white. One-fourth (56/200) of the participants reported wound-related itch. Wounds that itched were generally larger (t77.74 = -3.27; P = .002; d = 0.63; 95% confidence interval [CI], -1.01 to -0.25), had more tissue edema (t88.38 = -2.19; P = .031; 95% CI, -0.93 to -0.47), and demonstrated more granulation tissue in the wound base (t98.71 = 2.03; P = .045; 95% CI, 0.01-0.87), compared with wounds without itch. Greater itch was associated with wounds that had a moderate amount of exudate (P = .02) or necrotic tissue in the base. CONCLUSIONS: Wound itch was present in more severe wounds as evidenced by larger size, more tissue edema, and necrotic tissue. Understanding wound itch could promote wound healing and improve quality of life for persons with chronic wounds.


Assuntos
Prurido/etiologia , Prurido/terapia , Ferimentos e Lesões/complicações , Ferimentos e Lesões/terapia , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Assistência Ambulatorial , Doença Crônica , Estudos de Coortes , Intervalos de Confiança , Feminino , Seguimentos , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Monitorização Fisiológica/métodos , Prurido/fisiopatologia , Medição de Risco , Índice de Gravidade de Doença , Fatores Sexuais , Higiene da Pele/métodos , Resultado do Tratamento , Cicatrização/fisiologia , Ferimentos e Lesões/diagnóstico , Adulto Jovem
8.
Eye (Lond) ; 37(16): 3360-3366, 2023 11.
Artigo em Inglês | MEDLINE | ID: mdl-37076687

RESUMO

PURPOSE: To evaluate if anterior chamber depth (ACD) and lens thickness (LT) measured by two different devices are affected by different eye lengths. METHODS: ACD and LT of 251 eyes (44 hyperopic, 60 myopic, 147 emmetropic) of 173 patients received with an iOCT-guided femtosecond laser-assisted lens surgery (FLACS) and the IOL Master 700 were compared. RESULTS: ACD measured with the IOL Master 700 was -0.026 ± 0.125 mm smaller (p = 0.001) than that with the iOCT for all eye-groups (hyperopic: p = 0.601, emmetropic: p = 0.003; myopic: p = 0.094). However, differences in all groups were not clinically relevant. LT measurements (all eyes: -0.0642 ± 0.0504 mm) shows a statistically significant difference in all evaluated groups (p < 0.001). Only myopic eyes showed a clinically relevant difference in LT. CONCLUSION: The two devices show no clinically relevant differences in the eye-length groups (myopic, emmetropic, and hyperopic) for all ACD measurements. LT data shows a clinically relevant difference only for the group of myopic eyes.


Assuntos
Hiperopia , Miopia , Humanos , Refração Ocular , Tomografia de Coerência Óptica , Miopia/cirurgia , Emetropia , Hiperopia/cirurgia
9.
Resuscitation ; 193: 109946, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37634860

RESUMO

AIM: Understanding the public health burden of cardiac arrest (CA) is important to inform healthcare policies, particularly during healthcare crises such as the COVID-19 pandemic. This study aimed to analyse outcomes of in-hospital mortality and healthcare resource utilisation in adult patients with CA in the United States over the last decade prior to the COVID-19 pandemic. METHODS: The United States (US) National Inpatient Sample was utilised to identify hospitalised adult patients with CA between 2010 and 2019. Logistic and Poisson regression models were used to analyse outcomes by adjusting for 47 confounders. RESULTS: 248,754 adult patients with CA (without "Do Not Resuscitate"-orders) were included in this study, out of which 57.5% were male. In-hospital mortality was high with 51.2% but improved significantly from 58.3% in 2010 to 46.4% in 2019 (P < 0.001). Particularly, elderly patients, non-white patients and patients requiring complex therapy had a higher mortality rate. Although the average hospital LOS decreased by 11%, hospital expenses have increased by 13% between 2010 and 2019 (each P < 0.001), presumably due to more frequent use of mechanical circulatory support (MCS, e.g. ECMO from 2.6% to 8.7% or Impella® micro-axial flow pump from 1.8% to 14.2%). Strong disparities existed among patient age groups and ethnicities across the US. Of note, the number of young adults with CA and opioid-induced CA has almost doubled within the study period. CONCLUSION: Over the last ten years prior to the COVID-19 pandemic, CA-related survival has incrementally improved with shorter hospitalisations and increased medical expenses, while strong disparities existed among different age groups and ethnicities. National standards for CA surveillance should be considered to identify trends and differences in CA treatment to allow for standardised medical care.


Assuntos
COVID-19 , Parada Cardíaca , Adulto Jovem , Humanos , Masculino , Estados Unidos/epidemiologia , Idoso , Feminino , Pandemias , Parada Cardíaca/terapia , Mortalidade Hospitalar , Atenção à Saúde
10.
J Clin Med ; 12(14)2023 Jul 09.
Artigo em Inglês | MEDLINE | ID: mdl-37510689

RESUMO

Percutaneous left atrial appendage closure (LAAC) has emerged as a non-pharmacological alternative for stroke prevention in patients with atrial fibrillation (AF) not suitable for anticoagulation therapy. Real-world data on peri-procedural outcomes are limited. The aim of this study was to analyze outcomes of peri-procedural safety and healthcare resource utilization in 11,240 adult patients undergoing LAAC in the United States between 2016 and 2019. Primary outcomes (safety) were in-hospital ischemic stroke or systemic embolism (SE), pericardial effusion (PE), major bleeding, device embolization and mortality. Secondary outcomes (resource utilization) were adverse discharge disposition, hospital length of stay (LOS) and costs. Logistic and Poisson regression models were used to analyze outcomes by adjusting for 10 confounders. SE decreased by 97% between 2016 and 2019 [95% Confidence Interval (CI) 0-0.24] (p = 0.003), while a trend to lower numbers of other peri-procedural complications was determined. In-hospital mortality (0.14%) remained stable. Hospital LOS decreased by 17% (0.78-0.87, p < 0.001) and adverse discharge rate by 41% (95% CI 0.41-0.86, p = 0.005) between 2016 and 2019, while hospital costs did not significantly change (p = 0.2). Female patients had a higher risk of PE (OR 2.86 [95% CI 2.41-6.39]) and SE (OR 5.0 [95% CI 1.28-43.6]) while multi-morbid patients had higher risks of major bleeding (p < 0.001) and mortality (p = 0.031), longer hospital LOS (p < 0.001) and increased treatment costs (p = 0.073). Significant differences in all outcomes were observed between male and female patients across US regions. In conclusion, LAAC has become a safer and more efficient procedure. Significant sex differences existed across US regions. Careful considerations should be taken when performing LAAC in female and comorbid patients.

11.
Resuscitation ; 186: 109775, 2023 05.
Artigo em Inglês | MEDLINE | ID: mdl-36958632

RESUMO

BACKGROUND: Guidelines advocate the use of extracorporeal cardio-pulmonary resuscitation with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in selected patients with cardiac arrest. Effects of concomitant left-ventricular (LV) unloading with Impella® (ECMELLA) remain unclear. This is the first study to investigate whether treatment with ECMELLA was associated with improved outcomes in patients with refractory cardiac arrest caused by acute myocardial infarction (AMI). METHODS: This study was approved by the local ethical committee. Patients treated with ECMELLA at three centers between 2016 and 2021 were propensity score (PS)-matched to patients receiving VA-ECMO based on age, electrocardiogram rhythm, cardiac arrest location and Survival After Veno-Arterial ECMO (SAVE) score. Cox proportional-hazard and Poisson regression models were used to analyse 30-day mortality rate (primary outcome), hospital and intensive care unit (ICU) length of stay (LOS) (secondary outcomes). Sensitivity analyses on patient demographics and cardiac arrest parameters were performed. RESULTS: 95 adult patients were included in this study, out of whom 34 pairs of patients were PS-matched. ECMELLA treatment was associated with decreased 30-day mortality risk (Hazard Ratio [HR] 0.53 [95% Confidence Interval (CI) 0.31-0.91], P = 0.021), prolonged hospital (Incidence Rate Ratio (IRR) 1.71 [95% CI 1.50-1.95], P < 0.001) and ICU LOS (IRR 1.81 [95% CI 1.57-2.08], P < 0.001). LV ejection fraction significantly improved until ICU discharge in the ECMELLA group. Especially patients with prolonged low-flow time and high initial lactate benefited from additional LV unloading. CONCLUSIONS: LV unloading with Impella® concomitant to VA-ECMO therapy in patients with therapy-refractory cardiac arrest due to AMI was associated with improved patient outcomes.


Assuntos
Reanimação Cardiopulmonar , Parada Cardíaca , Infarto do Miocárdio , Adulto , Humanos , Infarto do Miocárdio/complicações , Reanimação Cardiopulmonar/efeitos adversos , Parada Cardíaca/terapia , Função Ventricular Esquerda , Mortalidade Hospitalar , Choque Cardiogênico/terapia , Estudos Retrospectivos
12.
J Cataract Refract Surg ; 48(6): 667-672, 2022 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-34486574

RESUMO

PURPOSE: To compare agreement of anterior segment parameter measurements using an intraoperative optical coherence tomography (iOCT) of a femtosecond laser (LenSx) during interface docking to the eye with preoperative Scheimpflug tomography (Pentacam AXL) and swept-source optical coherence tomography (SS-OCT) (IOLMaster 700). SETTING: Department of Ophthalmology, Goethe University, Frankfurt, Germany. DESIGN: Retrospective study. METHODS: Anterior segment measurements were performed in mydriasis prior to surgery using Scheimpflug tomography and SS-OCT. Postoperatively, iOCT images were analyzed using a modification of the FIJI image-processing program. Outcome measures included external anterior chamber depth (ACD), central corneal thickness (CCT), and central lens thickness (LT). RESULTS: 95 eyes of 66 patients who underwent planned OCT guided femtosecond laser-assisted lens surgery were included. The ACD measured with the iOCT was -0.011 ± 0.126 mm smaller (P = .389) than that with the SS-OCT and -0.059 ± 0.185 mm than with the Scheimpflug tomography (P = .003). The SS-OCT measured a -0.047 ± 0.146 mm smaller ACD than the Scheimpflug tomography (P = .002). The measurements of CCT using the iOCT and the Scheimpflug tomography (-0.705 ± 20.837 µm, P = .742) and the LT measurements using SS-OCT and iOCT (-0.050 ± 0.089 mm, P < .001) showed no clinically relevant difference. Only the ACD between the iOCT and the Scheimpflug tomography showed a clinically relevant difference. CONCLUSIONS: The comparison of the anterior segment parameters of iOCT with SS-OCT showed no clinically relevant differences regarding the ACD and the LT. However, Scheimpflug tomography vs iOCT measured a small clinically relevant difference for ACD. The iOCT showed no clinically relevant differences in anterior segment parameters compared with the SS-OCT. A small clinically relevant difference for ACD was found in comparison with that of a Scheimpflug device.


Assuntos
Cristalino , Tomografia de Coerência Óptica , Biometria/métodos , Córnea , Alemanha , Humanos , Reprodutibilidade dos Testes , Estudos Retrospectivos , Tomografia de Coerência Óptica/métodos
13.
J Wound Ostomy Continence Nurs ; 38(1): 46-54, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21287771

RESUMO

PURPOSE: The purpose of the study was to examine the symptom of itch and its relationship with chronic venous disease, pain, and quality of life. DESIGN: The study used an exploratory, cross-sectional design. METHODS: One hundred and sixty-one participants completed demographic, health, substance abuse, itch, and pain questionnaires and the SF-12v2 Health Survey to measure health related quality of life. RESULTS: Participants were mostly men (n=95, 59%), African American (113, 70.2%), and had a mean age of 44.19 years. A history of injection drug use was reported by 91.4%. Using the clinical score of the Clinical-Etiology-Anatomy-Pathophysiology (CEAP) Classification of the worst leg, the most common classification was Class 3, edema without skin changes (45.9%); 18.6% had severe venous disease (Classes 5 and 6). Eighty-eight participants (54.7%) reported itch somewhere on their body with 74 of them (45.9%) reporting itch on the legs or feet. Fourteen participants who reported itch of their legs or feet had wounds on the legs or feet. A positive correlation between magnitude of reported itch and CEAP clinical classification was noted (0.26, P =.025). This relationship was not strictly linear with itch increasing at a faster rate at higher levels of the CEAP classification. Persons with leg or feet itch had poorer health related quality of life, more comorbidities, and higher leg pain than those without itch. Because the SF-12v2 Health Survey is norm based, persons with itch were more than 1 standard deviation below the mean for the United States for their mental and physical health scores. CONCLUSIONS: Itch on the legs or feet is a clinically relevant problem that is related to the level of venous disease. Persons with lower extremity itch have higher pain ratings and lower quality of life.


Assuntos
Atitude Frente a Saúde , Dor/etiologia , Prurido/etiologia , Qualidade de Vida/psicologia , Insuficiência Venosa/complicações , Adulto , Negro ou Afro-Americano/psicologia , Negro ou Afro-Americano/estatística & dados numéricos , Idoso , Análise de Variância , Doença Crônica , Estudos Transversais , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Pessoa de Meia-Idade , Meio-Oeste dos Estados Unidos/epidemiologia , Enfermeiros Clínicos , Pesquisa Metodológica em Enfermagem , Dor/diagnóstico , Dor/epidemiologia , Dor/psicologia , Prurido/epidemiologia , Prurido/prevenção & controle , Prurido/psicologia , Higiene da Pele/enfermagem , Abuso de Substâncias por Via Intravenosa/complicações , Abuso de Substâncias por Via Intravenosa/epidemiologia , Insuficiência Venosa/classificação , Insuficiência Venosa/epidemiologia
14.
Wounds ; 2021 03 31.
Artigo em Inglês | MEDLINE | ID: mdl-33913822

RESUMO

BACKGROUND: Persons who inject drugs (PWID) in the groin, legs, and/or feet are at high risk for chronic venous ulcers (CVUs). The plasma C-reactive protein (CRP) level is a marker of systemic inflammation. OBJECTIVE: This pilot study examined CRP levels in plasma and CVU exudate of PWID. The aims were to (1) compare levels of CRP in plasma and exudate; (2) examine if the CRP level in exudate changed over 4 weeks with wound treatment; and (3) examine the relationship of the exudate CRP level with CVU area, CVU age, number of CVUs, and number of comorbidities. MATERIALS AND METHODS: Persons who inject drugs seeking wound care were enrolled in this Institutional Review Board approved prospective, longitudinal, descriptive study. A blood sample was collected on the first visit (week 1); the plasma was then separated. Wound exudate was collected on swabs during the first visit (week 1) and 4 weeks later (week 4). All samples were stored at -80° C. Samples were eluted from swabs using mass spectrometry grade water then aliquoted for CRP analysis. RESULTS: The participants of the study included 14 PWID (mean age, 62.14 ± 4.52 years; mean number of comorbidities, 5.71 ± 1.90; and mean number of ulcers 2.07 ± 1.07 that were present for a mean of 7.96 ± 11.91 years without healing). C-reactive protein level in plasma was a mean of 6.47 ± 8.56 mg/L, with lower levels found in wound exudate but highly correlated (rho = .925). Exudate CRP levels decreased from week 1 to week 4, and the 2 were highly correlated (rho = .895). Exudate CRP level week 1 was not significantly related to wound area, wound age, number of ulcers, or number of comorbidities. CONCLUSIONS: Plasma and exudate CRP levels were highly correlated. Exudate CRP levels decreased across time. Future large-scale wound healing studies should examine CRP levels over a longer duration and as they correlate to wound healing.

15.
Can J Public Health ; 110(5): 649-656, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31102235

RESUMO

OBJECTIVE: The Manitoba Infant Feeding Database (MIFD) is being piloted as a surveillance system leveraging infant vaccination visits as a point of contact to collect infant feeding data during the first year of life. The objective of this study was to assess data quality and acceptability of the MIFD as a sustainable population-based surveillance system. METHODS: Internal completeness and internal validity were measured to assess data quality. Internal completeness was defined as the number of completed data fields out of the total number of data fields. Internal validity was defined as the proportion of translation errors from one level of the system, the paper questionnaire, to the next, the electronic database. A survey assessed staff's acceptance of data collection and submission processes. RESULTS: A total of 947 records were reviewed. Data were 98.5% complete. Discrepancies were noted in 13.5% of data. The survey response rate was 78.4%. Nearly all respondents reported that the MIFD data collection tool was easy to use (96.6% agreed or strongly agreed). Whereas some challenges were identified, the majority were willing to continue with the MIFD data collection tool and process (93.1%). CONCLUSION: Results from this evaluation suggest that the MIFD data collection process worked well; however, data validation will require human resources. The MIFD approach provides a sustainable mechanism for collecting data on infant feeding for surveillance and research purposes.


Assuntos
Bases de Dados como Assunto , Comportamento Alimentar , Vigilância da População/métodos , Confiabilidade dos Dados , Humanos , Lactente , Manitoba , Projetos Piloto
16.
Ostomy Wound Manage ; 54(3): 18-27; quiz 28-9, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18382045

RESUMO

Unpleasant odor is a frequent and distressing concern of persons who have wounds, as well as their family members and caregivers. In some instances, standard nursing interventions such as increasing the frequency of dressing changes will not be sufficient to address wound malodor. A review of the literature to summarize research findings about topical metronidazole used to decrease wound odor was conducted. Fifteen (15) studies were identified: seven case reports/series; six descriptive longitudinal studies; and two controlled clinical trials. Metronidazole was used as a 1% solution or, more frequently, as a 0.75% or 0.80% gel. Two reported adverse effects were skin irritation and a burning sensation. Generally, topical metronidazole was reported to result in a reduction or eradication of wound odor, decrease in wound drainage, improvement in wound appearance, decrease in surrounding cellulitis, halting of tissue necrosis, and decrease in pain. Although nurses report success with sprinkling crushed metronidazole pills on wounds, no published reports of this method of topical application are available. Topical metronidazole may be considered as an option for the management of malodorous wounds and additional randomized controlled trials with adequate sample sizes and comparison to products noted to decrease odor are warranted. While topical metronidazole for the treatment of malodorous wounds presently is off-label, perhaps such studies will result in the addition of malodorous wounds to the list of its indications.


Assuntos
Anti-Infecciosos/uso terapêutico , Metronidazol/uso terapêutico , Odorantes/prevenção & controle , Infecção dos Ferimentos/tratamento farmacológico , Administração Cutânea , Administração Oral , Anti-Infecciosos/efeitos adversos , Exsudatos e Transudatos/efeitos dos fármacos , Humanos , Metronidazol/efeitos adversos , Papel do Profissional de Enfermagem , Avaliação em Enfermagem , Seleção de Pacientes , Ensaios Clínicos Controlados Aleatórios como Assunto , Projetos de Pesquisa , Segurança , Higiene da Pele/métodos , Higiene da Pele/enfermagem , Resultado do Tratamento , Cicatrização/efeitos dos fármacos , Infecção dos Ferimentos/enfermagem , Infecção dos Ferimentos/psicologia
17.
Wounds ; 30(1): 4-9, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29406292

RESUMO

INTRODUCTION: Wound-related itch can be a source of great discomfort for patients with chronic wounds. Although itch is common among patients with chronic wounds, it is an understudied phenomenon. A greater understanding of itch is needed in order for clinicians to more effectively manage it. OBJECTIVE: The purpose of this study is to identify descriptors for wound-related itch based on patient responses. METHODS: Data from structured interviews of patients with chronic wounds were analyzed. Those patients who described wound-related itch were asked to rate how much various descriptors matched their itch on a scale of 0 (not at all) to 4 (to a great extent). Analysis included descriptive statistics and principal components factor analysis. RESULTS: Fifty-six of 199 (28%) patients with wound-related itch rated descriptors, and 5 categories of descriptors were identified. A concise set of 15 descriptors of itch related to chronic wounds was defined from this. CONCLUSIONS: This list of descriptors for wound-related itch can be tested further for clinical use and for research purposes when wound-related itch is being explored.


Assuntos
Prurido/fisiopatologia , Ferimentos e Lesões/fisiopatologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Doença Crônica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prurido/diagnóstico , Prurido/etiologia , Prurido/psicologia , Qualidade de Vida , Índice de Gravidade de Doença , Inquéritos e Questionários , Ferimentos e Lesões/complicações , Ferimentos e Lesões/psicologia , Adulto Jovem
18.
Sci Rep ; 7: 40079, 2017 01 11.
Artigo em Inglês | MEDLINE | ID: mdl-28074838

RESUMO

Long-term torpor is an adaptive strategy that allows animals to survive harsh winter conditions. However, the impact that prolonged torpor has on cognitive function is poorly understood. Hibernation causes reduced synaptic activity and experiments with mammals reveal that this can have adverse effects on memories formed prior to hibernation. The impact of brumation, the winter dormancy that is observed in ectotherms, on memory remains unknown. The aim of this study was to examine whether an amphibian, the fire salamander (Salamandra salamandra), was able to retain learned spatial information after a period of brumation. Twelve fire salamanders were trained to make a simple spatial discrimination using a T-maze. All subjects learned the initial task. Upon reaching criterion, half of the subjects were placed into brumation for 100 days while the other half served as controls and were maintained under normal conditions. A post-brumation memory retention test revealed that animals from both conditions retained the learned response. Control tests showed that they solved the task using learned information and not olfactory cues. This finding contrasts with much of the mammalian research and suggests that the processes involved in prolonged torpor may have a fundamentally different impact on memory in mammals and amphibians.


Assuntos
Salamandra/fisiologia , Memória Espacial , Torpor , Animais , Fatores de Tempo
19.
BMJ Open ; 7(10): e017981, 2017 Oct 22.
Artigo em Inglês | MEDLINE | ID: mdl-29061626

RESUMO

INTRODUCTION: Breast feeding is associated with many health benefits for mothers and infants. But despite extensive public health efforts to promote breast feeding, many mothers do not achieve their own breastfeeding goals; and, inequities in breastfeeding rates persist between high and low-income mother-infant dyads. Developing targeted programme to support breastfeeding dyads and reduce inequities between mothers of different socioeconomic status are a priority for public health practitioners and health policy decision-makers; however, many jurisdictions lack the timely and comprehensive population-level data on infant-feeding practices required to monitor trends in breastfeeding initiation and duration. This protocol describes the establishment of a population-based infant-feeding database in the Canadian province of Manitoba, providing opportunities to develop and evaluate breastfeeding support programme. METHODS AND ANALYSIS: Routinely collected administrative health data on mothers' infant-feeding practices will be captured during regular vaccination visits using the Teleform fax tool, which converts handwritten information to an electronic format. The infant-feeding data will be linked to the Manitoba Population Research Data Repository, a comprehensive collection of population-based information spanning health, education and social services domains. The linkage will allow us to answer research questions about infant-feeding practices and to evaluate how effective current initiatives promoting breast feeding are. ETHICS AND DISSEMINATION: Approvals have been granted by the Health Research Ethics Board at the University of Manitoba. Our integrative knowledge translation approach will involve disseminating findings through government and community briefings, presenting at academic conferences and publishing in scientific journals.


Assuntos
Aleitamento Materno , Bases de Dados como Assunto , Promoção da Saúde/métodos , Mães/educação , Humanos , Modelos Logísticos , Manitoba , Análise Multivariada , Estudos Prospectivos , Saúde Pública/educação , Projetos de Pesquisa
20.
J Trauma Acute Care Surg ; 77(3 Suppl 1): S41-5, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25153054

RESUMO

BACKGROUND: Pediatric firearm injuries are an increasing source of morbidity. Firearm injuries in adolescents are common but not well studied in younger children. The aims were to describe the epidemiology of firearm injuries in patients 0 year to 18 years old, with a case study of patients 14 years or younger for determining shooting characteristics and epidemiologic trends. METHODS: Part 1 obtained data from hospital trauma registry. Inclusion criteria were patients 0 year to 18 years of age presenting from 2005 to 2010 with firearm injury and registry inclusion. Demographic and injury data were extracted. Part 2 included a retrospective review of patients 14 years or younger including hospital and emergency medical services records. Data from the group 0 year to 14 years included shooting and treatment details. Categorical variables were described using counts and percentages. Differences between the groups were assessed using odds ratios (ORs), along with 95%confidence intervals (CIs), extracted from logistic regression models. RESULTS: Registry query resulted in 456 patients (0-18 years), including 78 patients who are 14 years or younger. In the group of 0 to 18 years, 86% were male; 83% were black in the group of 15 to 18 years and 64% in the group 0 to 14 years. Overall death rate was 7%. Patients in the group of 15 years to 18 years were twice more likely (23% vs. 11%) to arrive via car or walk-in compared with the patients in the group of 0 year to 14 years (OR, 2.32;95% CI, 1.07-5.03). Patients in the group of 0 year to 14 years were almost four times more likely to be shot at home compared with those who are 15 years to 18 years (OR, 3.76; 95% CI, 2.29-6.19). Patients in the group of 5 years to 9 years were six times more likely to have multiple injury sites compared with those who are 10 years to 14 years (OR, 6.26; 95% CI, 1.26-31.09). Only 13% had documented child protective services notification. CONCLUSION: Results from this study suggest that firearm injuries differ in younger patients compared with adolescents. The younger subset was more likely to be shot at home versus public settings. Hospital and emergency medical services records lacked important shooting details often found in crime scene reports, which are necessary for the development of effective crime and prevention strategies.


Assuntos
Ferimentos por Arma de Fogo/epidemiologia , Adolescente , Fatores Etários , Criança , Feminino , Humanos , Masculino , Estudos Retrospectivos
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