Detalhe da pesquisa
1.
CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway.
J Biol Chem
; 295(50): 17310-17322, 2020 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037071
2.
Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver.
Mol Syst Biol
; 16(5): e9156, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407006
3.
The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions.
Genome Res
; 27(6): 985-996, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28400425
4.
Hepatic PPARα is critical in the metabolic adaptation to sepsis.
J Hepatol
; 70(5): 963-973, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30677458
5.
Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα.
Nucleic Acids Res
; 44(22): 10539-10553, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27576532
6.
PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis.
J Hepatol
; 63(1): 164-73, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25703085
7.
The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα.
Metabolism
; 151: 155720, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37926201
8.
p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Blood
; 118(9): 2556-66, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21636855
9.
PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB.
Proc Natl Acad Sci U S A
; 106(18): 7397-402, 2009 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19376972
10.
Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis.
Nat Commun
; 13(1): 5324, 2022 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36088459
11.
NASH-related increases in plasma bile acid levels depend on insulin resistance.
JHEP Rep
; 3(2): 100222, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33615207
12.
Rimonabant, a selective cannabinoid CB1 receptor antagonist, inhibits atherosclerosis in LDL receptor-deficient mice.
Arterioscler Thromb Vasc Biol
; 29(1): 12-8, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18845788
13.
Plasma BCAA Changes in Patients With NAFLD Are Sex Dependent.
J Clin Endocrinol Metab
; 105(7)2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32271385
14.
Control of cell death/survival balance by the MET dependence receptor.
Elife
; 92020 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32091387
15.
Phosphorylation of farnesoid X receptor by protein kinase C promotes its transcriptional activity.
Mol Endocrinol
; 22(11): 2433-47, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18755856
16.
Cross-talk between statins and PPARalpha in cardiovascular diseases: clinical evidence and basic mechanisms.
Trends Cardiovasc Med
; 18(3): 73-8, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18436144
17.
Acute antiinflammatory properties of statins involve peroxisome proliferator-activated receptor-alpha via inhibition of the protein kinase C signaling pathway.
Circ Res
; 98(3): 361-9, 2006 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16397146
18.
Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.
Diabetes
; 55(6): 1605-13, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16731822
19.
The RXR agonist bexarotene improves cholesterol homeostasis and inhibits atherosclerosis progression in a mouse model of mixed dyslipidemia.
Arterioscler Thromb Vasc Biol
; 26(12): 2731-7, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17008586
20.
Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects.
J Clin Endocrinol Metab
; 102(10): 3783-3794, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28938455