Detalhe da pesquisa
1.
Smad2/3-pathway ligand trap luspatercept enhances erythroid differentiation in murine ß-thalassaemia by increasing GATA-1 availability.
J Cell Mol Med
; 24(11): 6162-6177, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32351032
2.
Follistatin-288-Fc Fusion Protein Promotes Localized Growth of Skeletal Muscle.
J Pharmacol Exp Ther
; 368(3): 435-445, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30563942
3.
Use Of Ankle Immobilization In Evaluating Treatments To Promote Longitudinal Muscle Growth In Mice.
Muscle Nerve
; 58(5): 718-725, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29981243
4.
Soluble activin receptor type IIB decoy receptor differentially impacts murine osteogenesis imperfecta muscle function.
Muscle Nerve
; 57(2): 294-304, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28555931
5.
Treatment with ActRIIB-mFc Produces Myofiber Growth and Improves Lifespan in the Acta1 H40Y Murine Model of Nemaline Myopathy.
Am J Pathol
; 186(6): 1568-81, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102768
6.
A Selective Transforming Growth Factor-ß Ligand Trap Attenuates Pulmonary Hypertension.
Am J Respir Crit Care Med
; 194(9): 1140-1151, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27115515
7.
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine ß-thalassemia.
Blood
; 123(25): 3864-72, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24795345
8.
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength.
Proc Natl Acad Sci U S A
; 109(30): 12207-12, 2012 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22761317
9.
Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.
J Biol Chem
; 286(34): 30034-46, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737454
10.
Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension.
Sci Rep
; 12(1): 7803, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35551212
11.
Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb.
J Biol Chem
; 285(27): 21037-48, 2010 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385559
12.
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity.
Proc Natl Acad Sci U S A
; 105(19): 7082-7, 2008 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18460605
13.
Functionally diverse heteromeric traps for ligands of the transforming growth factor-ß superfamily.
Sci Rep
; 11(1): 18341, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34526551
14.
ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders.
J Clin Invest
; 131(4)2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33586684
15.
A New Polygenic Model for Nonfamilial Colorectal Cancer Inheritance Based on the Genetic Architecture of the Azoxymethane-Induced Mouse Model.
Genetics
; 214(3): 691-702, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31879319
16.
ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension.
Sci Transl Med
; 12(543)2020 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32404506
17.
Skeletal Response to Soluble Activin Receptor Type IIB in Mouse Models of Osteogenesis Imperfecta.
J Bone Miner Res
; 33(10): 1760-1772, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29813187
18.
Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage.
Mol Cell Biol
; 24(20): 8907-16, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15456865
19.
Inhibition of ALK1 signaling with dalantercept combined with VEGFR TKI leads to tumor stasis in renal cell carcinoma.
Oncotarget
; 7(27): 41857-41869, 2016 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27248821
20.
Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: effects of dose, route, and diet.
Toxicol Sci
; 88(2): 340-5, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16150884