Detalhe da pesquisa
1.
Chemoproteomic Profiling Maps Zinc-Dependent Cysteine Reactivity.
Chem Res Toxicol
; 37(4): 620-632, 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38484110
2.
Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway.
J Am Chem Soc
; 143(48): 20332-20342, 2021 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34817176
3.
Chemoproteomics-Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism.
Angew Chem Int Ed Engl
; 60(6): 3071-3079, 2021 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33035395
4.
Correction: Zwergel et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers 2020, 12, 447.
Cancers (Basel)
; 16(6)2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38539577
5.
Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum.
iScience
; 26(2): 105940, 2023 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36718363
6.
Clinical Antiviral Drug Arbidol Inhibits Infection by SARS-CoV-2 and Variants through Direct Binding to the Spike Protein.
ACS Chem Biol
; 16(12): 2845-2851, 2021 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34792325
7.
Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells.
Eur J Med Chem
; 186: 111829, 2020 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31757526
8.
Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex.
Cell Chem Biol
; 27(5): 586-597.e12, 2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32330443
9.
Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs.
ACS Chem Biol
; 15(4): 952-961, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32191434
10.
Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation.
Cancers (Basel)
; 12(2)2020 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32075099
11.
Identification of novel quinazoline derivatives as potent antiplasmodial agents.
Eur J Med Chem
; 161: 277-291, 2019 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30366254
12.
Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Philos Trans R Soc Lond B Biol Sci
; 373(1748)2018 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29685976
13.
DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies.
Biochem Pharmacol
; 129: 1-13, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27956110
14.
Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.
J Med Chem
; 60(11): 4665-4679, 2017 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28463515
15.
Compounds for use in the treatment of mycobacterial infections: a patent evaluation (WO2014049107A1).
Expert Opin Ther Pat
; 25(6): 729-35, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25752488