The role of lack of grandparental support in perinatal depression.

BACKGROUND: Low social support has been identified as a risk factor for perinatal mental health problems. However, previous studies mainly focused on partner support or general social support and neglected the roles of grandparents. Here, we examine whether a lack of grandparental support is related to increased risk of a diagnosis of perinatal depression. In addition, we examine whether poor grandparental support is related to more depressive symptoms in mothers with and without previously diagnosed perinatal depression and whether perceived grandparental support buffers against parenting difficulties in mothers with perinatal depression. METHODS: The sample was drawn from an Australian pregnancy cohort study and consisted of 725 women, including 230 women who met criteria for Major Depression. At 12 months postpartum, women reported on grandparental geographical proximity and hours of grandparental childcare support. Perceived grandparental support was assessed with the Postpartum Social Support Questionnaire and parenting difficulties and depressive symptoms with the Parenting Stress Index and the Edinburgh Postnatal Depression Scale. RESULTS: Perceived grandparental support was related to fewer depressive symptoms among mothers with perinatal depression. In addition, higher levels of perceived grandparental support were related to lower parenting stress in mothers with and without perinatal depression. LIMITATIONS: Intergenerational conflicts and quality of grandparenting were not assessed. CONCLUSIONS: Our findings indicate that supportive grandparents may prevent the development of more severe perinatal depression in mothers experiencing perinatal mental health problems. Future studies should examine whether involving grandparents in treatment may add to the effectiveness of existing perinatal mental health interventions.

Foraging for the self: Environment selection for agency inference.

Sometimes agents choose to occupy environments that are neither traditionally rewarding nor worth exploring, but which rather promise to help minimise uncertainty related to what they can control. Selecting environments that afford inferences about agency seems a foundational aspect of environment selection dynamics - if an agent can't form reliable beliefs about what they can and can't control, then they can't act efficiently to achieve rewards. This relatively neglected aspect of environment selection is important to study so that we can better understand why agents occupy certain environments over others - something that may also be relevant for mental and developmental conditions, such as autism. This online experiment investigates the impact of uncertainty about agency on the way participants choose to freely move between two environments, one that has greater irreducible variability and one that is more complex to model. We hypothesise that increasingly erroneous predictions about the expected outcome of agency-exploring actions can be a driver of switching environments, and we explore which type of environment agents prefer. Results show that participants actively switch between the two environments following increases in prediction error, and that the tolerance for prediction error before switching is modulated by individuals' autism traits. Further, we find that participants more frequently occupy the variable environment, which is predicted by greater accuracy and higher confidence than the complex environment. This is the first online study to investigate relatively unconstrained ongoing foraging dynamics in support of judgements of agency, and in doing so represents a significant methodological advance.

Body as First Teacher: The Role of Rhythmic Visceral Dynamics in Early Cognitive Development.

Embodied cognition-the idea that mental states and processes should be understood in relation to one's bodily constitution and interactions with the world-remains a controversial topic within cognitive science. Recently, however, increasing interest in predictive processing theories among proponents and critics of embodiment alike has raised hopes of a reconciliation. This article sets out to appraise the unificatory potential of predictive processing, focusing in particular on embodied formulations of active inference. Our analysis suggests that most active-inference accounts invoke weak, potentially trivial conceptions of embodiment; those making stronger claims do so independently of the theoretical commitments of the active-inference framework. We argue that a more compelling version of embodied active inference can be motivated by adopting a diachronic perspective on the way rhythmic physiological activity shapes neural development in utero. According to this visceral afferent training hypothesis, early-emerging physiological processes are essential not only for supporting the biophysical development of neural structures but also for configuring the cognitive architecture those structures entail. Focusing in particular on the cardiovascular system, we propose three candidate mechanisms through which visceral afferent training might operate: (a) activity-dependent neuronal development, (b) periodic signal modeling, and (c) oscillatory network coordination.

Agency in schizophrenia and autism: a systematic review.

Introduction: Previous research suggests that altered experiences of agency are an underlying vulnerability in both schizophrenia and autism. Here, we explore agency as a potential transdiagnostic factor by conducting a systematic review of existing literature investigating agency in autism and schizophrenia individually and together. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted three systematic searches on PsycINFO, Embase, Medline, PubMed and Web of Science to identify studies that investigated (1) agency in schizophrenia, (2) agency in autism, and (3) agency in both schizophrenia and autism. Results: A total of 31 articles met eligibility criteria for inclusion and data extraction, with 24 measuring agency in schizophrenia, 7 investigating agency in autism, and no articles comparing the two. Results show that, compared to control populations, agency is significantly different in every identified schizophrenia study and generally not significantly different in autism. Discussion: Importantly, we identified a lack of studies using common tasks and a disproportionate number of studies investigating different dimensions of agency across the two conditions, resulting in limited grounds for valid comparison. Systematic review registration: Prospero, CRD42021273373.

Cognitive training and remediation interventions for substance use disorders: a Delphi consensus study.

AIMS: Substance use disorders (SUD) are associated with cognitive deficits that are not always addressed in current treatments, and this hampers recovery. Cognitive training and remediation interventions are well suited to fill the gap for managing cognitive deficits in SUD. We aimed to reach consensus on recommendations for developing and applying these interventions. DESIGN, SETTING AND PARTICIPANTS: We used a Delphi approach with two sequential phases: survey development and iterative surveying of experts. This was an on-line study. During survey development, we engaged a group of 15 experts from a working group of the International Society of Addiction Medicine (Steering Committee). During the surveying process, we engaged a larger pool of experts (n = 54) identified via recommendations from the Steering Committee and a systematic review. MEASUREMENTS: Survey with 67 items covering four key areas of intervention development: targets, intervention approaches, active ingredients and modes of delivery. FINDINGS: Across two iterative rounds (98% retention rate), the experts reached a consensus on 50 items including: (i) implicit biases, positive affect, arousal, executive functions and social processing as key targets of interventions; (ii) cognitive bias modification, contingency management, emotion regulation training and cognitive remediation as preferred approaches; (iii) practice, feedback, difficulty-titration, bias modification, goal-setting, strategy learning and meta-awareness as active ingredients; and (iv) both addiction treatment work-force and specialized neuropsychologists facilitating delivery, together with novel digital-based delivery modalities. CONCLUSIONS: Expert recommendations on cognitive training and remediation for substance use disorders highlight the relevance of targeting implicit biases, reward, emotion regulation and higher-order cognitive skills via well-validated intervention approaches qualified with mechanistic techniques and flexible delivery options.

How selves differ within and across cognitive domains: self-prioritisation, self-concept, and psychiatric traits.

BACKGROUND: How we build and maintain representations of ourselves involves both explicit features which are consciously accessible on reflection and implicit processes which are not, such as attentional biases. Understanding relations between different ways of measuring self-cognition both within and across such cognitive domains is important for understanding how selves may differ from one another, and whether self-cognition is best understood as largely uni-dimensional or more multi-dimensional. Further, uncovering this structure should inform research around how self-cognition relates to psychiatric and psychological conditions. This study explores the relations between different constructs of self-cognition and how variability within them relates to psychiatric traits. METHODS: Our final dataset includes within-subject (n = 288, general population) measures of explicit self-concept (using both the Self Concept Clarity Scale and Self Concept and Identity Measure), implicit self-prioritisation in a shape-label matching task (for both reaction time and sensitivity) and measurement of traits for five psychiatric conditions (autism, borderline personality disorder, schizophrenia, depression and anxiety). We first test whether self-cognitive measures within and across domains are correlated within individuals. We then test whether these dimensions of self-cognition support a binary distinction between psychiatric conditions that either are or are not characterised in terms of self, or whether they support self-cognition as transdiagnostically predictive of the traits associated with psychiatric conditions. To do this we run a series of planned correlations, regressions, and direct correlation comparison statistics. RESULTS: Results show that implicit self-prioritisation measures were not correlated with the explicit self-concept measures nor the psychiatric trait measures. In contrast, all the psychiatric traits scores were predicted, to varying degrees, by poorer explicit self-concept quality. Specifically, borderline personality disorder traits were significantly more strongly associated with composite explicit self-concept measures than any of depression, anxiety, or autism traits scores were. CONCLUSIONS: Our results suggest that selves can differ considerably, along different cognitive dimensions. Further, our results show that self-cognition may be a promising feature to include in future dimensional characterisations of psychiatric conditions, but care should be taken to choose relevant self-cognitive domains.

The effect of uncertainty on prediction error in the action perception loop.

Among all their sensations, agents need to distinguish between those caused by themselves and those caused by external causes. The ability to infer agency is particularly challenging under conditions of uncertainty. Within the predictive processing framework, this should happen through active control of prediction error that closes the action-perception loop. Here we use a novel, temporally-sensitive, behavioural proxy for prediction error to show that it is minimised most quickly when volatility is high and when participants report agency, regardless of the accuracy of the judgement. We demonstrate broad effects of uncertainty on accuracy of agency judgements, movement, policy selection, and hypothesis switching. Measuring autism traits, we find differences in policy selection, sensitivity to uncertainty and hypothesis switching despite no difference in overall accuracy.

A preliminary investigation of sound-field amplification as an inclusive classroom adjustment for children with and without Autism Spectrum Disorder.

PURPOSE: This study aimed to determine if sound-field amplification (SFA) could be used as an inclusive classroom adjustment to support primary school students with and without Autism Spectrum Disorder (ASD). METHODS: A two-group, randomised controlled trial (RCT) with crossover was conducted involving 13 students with ASD (9 males, aged 7.6 to 8.4 years) and 17 typically progressing students without ASD (7 males, aged 7.6 to 9.3 years) from 10 primary schools in and near to Brisbane, Australia. Eighteen of these children had an SFA system in their classrooms in semester one and 12 in semester two of their fourth year of formal schooling (Year 3). Potential proximate benefits were assessed using teacher questionnaire and video analysis of student listening behaviours. Potential distant benefits were assessed using measures of phonological processing in quiet and in noise, attention, memory, and educational achievement. RESULTS: Potential proximate benefits were observed for all students with teachers rating student listening behaviours higher with SFA versus without SFA. Potential distant benefits were observed for students with ASD who showed greater improvements in one area of phonological processing (blending nonsense words in noise) following SFA versus no SFA. No other potential proximate or distant benefits following SFA were observed. CONCLUSIONS: SFA could be used as an inclusive classroom adjustment to support some primary school students with and without ASD by potentially putting those students in a better position to learn, but their learning must still take place over time and realistic expectations of what can reasonably be achieved by SFA alone are needed.

Oculomotor deficits in attention deficit hyperactivity disorder (ADHD): A systematic review and comprehensive meta-analysis.

Atypical motor coordination and cognitive processes, such as response inhibition and working memory, have been extensively researched in individuals with attention deficit hyperactivity disorder (ADHD). Oculomotor neural circuits overlap extensively with regions involved in motor planning and cognition, therefore studies of oculomotor function may offer unique insights into motor and cognitive control in ADHD. We performed a series of pairwise meta-analyses based on data from 26 oculomotor studies in ADHD to examine whether there were differences in performance on visually-guided saccade, gap, antisaccade, memory-guided, pursuit eye movements and fixation tasks. These analyses revealed oculomotor disturbances in ADHD, particularly for difficulties relating to saccade inhibition, memorizing visual target locations and initiating antisaccades. There was no evidence for pursuit eye movement disturbances or saccade dysmetria. Investigating oculomotor abnormalities in ADHD may provide insight into top-down cognitive control processes and motor control, and may serve as a promising biomarker in ADHD research and clinical practice.

Explaining hyper-sensitivity and hypo-responsivity in autism with a common predictive coding-based mechanism.

Ward's signal detection theory-based framework elucidates some aspects of interindividual differences in sensitivity, but, we argue, obscures others. Specifically, it disregards the important challenge of inferring the meaning of sensory inputs. Within Bayesian predictive coding accounts, the meaning is given by inferences to more deeply hidden causes of sensory inputs and is generally the basis for initiating context-appropriate (e.g., social) behavior. As such, when inference of hierarchical causes is hampered, as accounts of autism based on deficient precision estimation imply, a form of hyporesponsivity can emerge (together with the hypersensitivity already highlighted by Ward).