MP-AzeFlu provides rapid and effective allergic rhinitis control: results of a non-interventional study in Romania.

BACKGROUND: Allergic Rhinitis and its Impact on Asthma (ARIA) and the European Union (EU) recommend a shift to guide allergic rhinitis (AR) treatment decisions from symptom severity to disease control, using a simple visual analogue scale (VAS). Using this VAS we assessed, in a real-life study in Romania, the effectiveness of MP-AzeFlu nasal spray. METHODOLOGY: In this multi-centre, prospective, non-interventional study, 253 patients (over 11 years old) with moderate-to-severe AR were prescribed MP-AzeFlu and assessed their symptoms on a VAS (0 (not at all bothersome) to 100 mm (very bothersome)) on Days 0, 1, 3, 7 and 14. The proportion of patients who achieved a defined VAS score cut-off for well-controlled (38 mm) AR were also calculated. Patients perception of disease control was assessed on Day 3. RESULTS: MP-AzeFlu use was associated with a mean (standard deviation) VAS score reduction from 78.4 (15.1) mm at baseline to 14.7 (15.1) mm on the last day. Effectiveness was consistent irrespective of disease severity, phenotype or patient age. 83.4% of patients achieved the smaller than 39 mm well-controlled VAS score cut-off by last day and 95.2% considered their symptoms to be well- or partly controlled at Day 3. CONCLUSIONS: MP-AzeFlu provided rapid, effective and sustained AR symptom control in a real-life setting in Romania, irrespective of severity, phenotype or patient age, aligning with ARIA and EU recommendations and supporting the position of MP-AzeFlu as the drug of choice for the treatment of moderate-to-severe AR.

The MRI fine evaluation of cervical lymphadenopathies and associated oral cavity pathological conditions.

The aim of this paper is to point out the value of MRI in diagnostic assessment of cervical lymphadenopathies and associated oral cavity pathological conditions. We used a statistic retrospective method to evaluate the results obtained after MRI examinations of 64 patients diagnosed with oral cavity pathology and cervical lymphadenopathies. In all cases the MRI exams detected the presence of cervical lymphadenopathies, their topoanatomic sites and oral cavity pathological entities that produced them. Due to fine characterization abilities by internal signal variation. MRI is the method of choice in daily practice for diagnosing, evaluation and staging of oral cavity pathology and cervical lymphadenopathies. Due to fine capacities of detecting internal signal variations in soft tissues or visceral parenchyma, MRI has high abilities in diagnostic assessment of oral cavity pathologies being a daily method of choice for diagnosing, evaluation and staging, with great value in any morbid entity.