Detalhe da pesquisa
1.
Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology.
Brief Bioinform
; 25(3)2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557676
2.
Virtual clinical trials via a QSP immuno-oncology model to simulate the response to a conditionally activated PD-L1 targeting antibody in NSCLC.
J Pharmacokinet Pharmacodyn
; 2024 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38858306
3.
Vascular phenotyping of the invasive front in breast cancer using a 3D angiogenesis atlas.
Microvasc Res
; 149: 104555, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37257688
4.
Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model.
PLoS Comput Biol
; 18(7): e1010254, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35867773
5.
A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology.
PLoS Comput Biol
; 15(11): e1007468, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31738746
6.
Suppression of Ocular Vascular Inflammation through Peptide-Mediated Activation of Angiopoietin-Tie2 Signaling.
Int J Mol Sci
; 21(14)2020 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32708100
7.
Mechanistic Computational Models of MicroRNA-Mediated Signaling Networks in Human Diseases.
Int J Mol Sci
; 20(2)2019 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30669429
8.
Human expression patterns: qualitative and quantitative analysis of thrombospondin-1 under physiological and pathological conditions.
J Cell Mol Med
; 22(4): 2086-2097, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29441713
9.
Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis.
Breast Cancer Res
; 20(1): 54, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29898755
10.
Computational modeling of synergistic interaction between αVß3 integrin and VEGFR2 in endothelial cells: Implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides.
J Theor Biol
; 455: 212-221, 2018 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30036530
11.
Modeling triple-negative breast cancer heterogeneity: Effects of stromal macrophages, fibroblasts and tumor vasculature.
J Theor Biol
; 452: 56-68, 2018 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29750999
12.
Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells.
PLoS Comput Biol
; 13(2): e1005332, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28178265
13.
Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.
PLoS Comput Biol
; 13(1): e1005272, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28045898
14.
Immunoactivating the tumor microenvironment enhances immunotherapy as predicted by integrative computational model.
Proc Natl Acad Sci U S A
; 117(9): 4447-4449, 2020 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32102915
15.
Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer.
PLoS Comput Biol
; 11(11): e1004612, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26588727
16.
PADPIN: protein-protein interaction networks of angiogenesis, arteriogenesis, and inflammation in peripheral arterial disease.
Physiol Genomics
; 47(8): 331-43, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26058837
17.
Vasculature-specific MRI reveals differential anti-angiogenic effects of a biomimetic peptide in an orthotopic breast cancer model.
Angiogenesis
; 18(2): 125-36, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25408417
18.
Crosstalk between cancer cells and blood endothelial and lymphatic endothelial cells in tumour and organ microenvironment.
Expert Rev Mol Med
; 17: e3, 2015 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25634527
19.
A systems biology view of blood vessel growth and remodelling.
J Cell Mol Med
; 18(8): 1491-508, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24237862
20.
A bioimage informatics based reconstruction of breast tumor microvasculature with computational blood flow predictions.
Microvasc Res
; 91: 8-21, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24342178