Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice.

Murphy, Judith T; Burey, Andre P; Beebe, Amy M; Gu, Danling; Presta, Leonard G; Merghoub, Taha; Wolchok, Jedd D.

Blood ; 123(14): 2172-80, 2014 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-24558202

2.

An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity.

Weisser, Nina E; Sanches, Mario; Escobar-Cabrera, Eric; O'Toole, Jason; Whalen, Elizabeth; Chan, Peter W Y; Wickman, Grant; Abraham, Libin; Choi, Kate; Harbourne, Bryant; Samiotakis, Antonios; Rojas, Andrea Hernández; Volkers, Gesa; Wong, Jodi; Atkinson, Claire E; Baardsnes, Jason; Worrall, Liam J; Browman, Duncan; Smith, Emma E; Baichoo, Priya; Cheng, Chi Wing; Guedia, Joy; Kang, Sohyeong; Mukhopadhyay, Abhishek; Newhook, Lisa; Ohrn, Anders; Raghunatha, Prajwal; Zago-Schmitt, Matteo; Schrag, Joseph D; Smith, Joel; Zwierzchowski, Patricia; Scurll, Joshua M; Fung, Vincent; Black, Sonia; Strynadka, Natalie C J; Gold, Michael R; Presta, Leonard G; Ng, Gordon; Dixit, Surjit.

Nat Commun ; 14(1): 1394, 2023 03 13.

Artigo em Inglês | MEDLINE | ID: mdl-36914633

3.

TCR mimic compounds for pHLA targeting with high potency modalities in oncology.

Gerber, Hans-Peter; Presta, Leonard G.

Front Oncol ; 12: 1027548, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36338746

4.

Molecular engineering and design of therapeutic antibodies.

Presta, Leonard G.

Curr Opin Immunol ; 20(4): 460-70, 2008 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-18656541

5.

Engineering of therapeutic antibodies to minimize immunogenicity and optimize function.

Presta, Leonard G.

Adv Drug Deliv Rev ; 58(5-6): 640-56, 2006 Aug 07.

Artigo em Inglês | MEDLINE | ID: mdl-16904789

6.

Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.

Vajdos, Felix F; Adams, Camellia W; Breece, Timothy N; Presta, Leonard G; de Vos, Abraham M; Sidhu, Sachdev S.

J Mol Biol ; 320(2): 415-28, 2002 Jul 05.

Artigo em Inglês | MEDLINE | ID: mdl-12079396

7.

Simple quantitative live cell and anti-idiotypic antibody based ELISA for humanized antibody directed to cell surface protein CD20.

Hong, Kyu; Presta, Leonard G; Lu, Yanmei; Penn, Ashley; Adams, Camellia; Chuntharapai, Anan; Yang, Jihong; Wong, Wai Lee; Meng, Y Gloria.

J Immunol Methods ; 294(1-2): 189-97, 2004 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-15604027

8.

Engineering antibodies for therapy.

Presta, Leonard G.

Curr Pharm Biotechnol ; 3(3): 237-56, 2002 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-12164480

9.

Celebrating diversity and mimicking maturation.

Presta, Leonard G.

Nat Biotechnol ; 20(11): 1096-7, 2002 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-12410253

10.

Identification of IgG(1) variants with increased affinity to FcÎ³RIIIa and unaltered affinity to FcÎ³RI and FcRn: comparison of soluble receptor-based and cell-based binding assays.

Lu, Yanmei; Vernes, Jean-Michel; Chiang, Nancy; Ou, Qinglin; Ding, Jiabing; Adams, Camellia; Hong, Kyu; Truong, Bao-Tran; Ng, Domingos; Shen, Amy; Nakamura, Gerald; Gong, Qian; Presta, Leonard G; Beresini, Maureen; Kelley, Bob; Lowman, Henry; Wong, Wai Lee; Meng, Y Gloria.

J Immunol Methods ; 365(1-2): 132-41, 2011 Feb 28.

Artigo em Inglês | MEDLINE | ID: mdl-21185301

11.

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease.

Petkova, Stefka B; Akilesh, Shreeram; Sproule, Thomas J; Christianson, Gregory J; Al Khabbaz, Hana; Brown, Aaron C; Presta, Leonard G; Meng, Y Gloria; Roopenian, Derry C.

Int Immunol ; 18(12): 1759-69, 2006 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-17077181

12.

Selection, design, and engineering of therapeutic antibodies.

Presta, Leonard G.

J Allergy Clin Immunol ; 116(4): 731-6; quiz 737, 2005 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-16210043

13.

Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity.

Shields, Robert L; Lai, Jadine; Keck, Rodney; O'Connell, Lori Y; Hong, Kyu; Meng, Y Gloria; Weikert, Stefanie H A; Presta, Leonard G.

J Biol Chem ; 277(30): 26733-40, 2002 Jul 26.

Artigo em Inglês | MEDLINE | ID: mdl-11986321

Portal de Pesquisa da BVS Enfermagem

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar:

Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice.

An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity.

TCR mimic compounds for pHLA targeting with high potency modalities in oncology.

Molecular engineering and design of therapeutic antibodies.

Engineering of therapeutic antibodies to minimize immunogenicity and optimize function.

Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.

Simple quantitative live cell and anti-idiotypic antibody based ELISA for humanized antibody directed to cell surface protein CD20.

Engineering antibodies for therapy.

Celebrating diversity and mimicking maturation.

Identification of IgG(1) variants with increased affinity to FcÎ³RIIIa and unaltered affinity to FcÎ³RI and FcRn: comparison of soluble receptor-based and cell-based binding assays.

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease.

Selection, design, and engineering of therapeutic antibodies.

Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity.