Does physical activity lower the risk for metabolic syndrome: a longitudinal study of physically active older women.

BACKGROUND: The associations between physical activity and metabolic syndrome (MetS) have been mainly found in cross-sectional studies. The aim of this longitudinal study was to examine the relationship between meeting step-based guidelines and changes in the risk of metabolic syndrome. METHODS: This study included data from older women (baseline age 62.9 ± 4.3 years) from a 7-year longitudinal study in Central Europe. At baseline and follow-up, physical activity was measured by an accelerometer, and the risk for MetS was assessed according to the NCEP-ATP III criteria. In 59 women, multivariate repeated measures ANOVA was used to compare differences in changes in the risk of MetS in groups based on meeting step-based guidelines (10,000 steps/day and 9000 steps/day for women aged <65 and ≥ 65 years, respectively). RESULTS: Over 7 years, steps/day increased from 10,944 ± 3560 to 11,652 ± 4865, and the risk of MetS decreased from 41 to 12% in our sample. Women who longitudinally met step-based guidelines had a significantly higher mean concentration of high-density cholesterol (HDL-C) (64.5 and 80.3 mg/dL at baseline and follow-up, respectively) and a lower concentration of triglycerides (TGs) (158.3 and 123.8 mg/dL at baseline and follow-up, respectively) at follow-up compared to baseline. Moreover, women who increased their daily steps over 7 years to the recommended steps/day value significantly decreased the concentration of TGs (158.3 mg/dL and 123.8 mg/dL at baseline and follow-up, respectively). CONCLUSIONS: Our study might suggest that the long-term meeting of step-based guidelines or an increase in daily steps/day to achieve the recommended value could be related to a lower risk of MetS, specifically in concentrations of HDL-C and TG. These findings may help in designing interventions aiming to decrease the risk of MetS in older women.

Adiposity and changes in movement-related behaviors in older adult women in the context of the built environment: a protocol for a prospective cohort study.

BACKGROUND: In older adults, sedentary behaviors increase while physical activity decreases over time following the compositional nature of 24-h behaviors. These changes in movement-related behaviors (MRBs) might be associated with unhealthy weight gain and several health comorbidities. However, information is lacking on how obesity influences longitudinal changes in the composition of MRBs in older adults. Furthermore, the moderating effect of the built environment on prospective associations between obesity and MRBs in older adults is not fully understood. Therefore, using an integrated time-use approach, this study aims to identify prospective associations between obesity and MRBs together with an assessment of the moderating effect of the built environment in elderly women. METHODS: The study was designed as a prospective 7-year follow-up study. It is based on two previous cross-sectional studies that enable the use of participant data (women aged 60+ years, n = 409) as a baseline dataset in the current study. All methods designed for 7-year follow-up are based on previous studies. The data collection comprises device-based measurement of MRBs (ActiGraph GT1M accelerometer), objective assessment of body adiposity (multi-frequency bioelectrical impedance analysis), subjective assessment of the built environment (NEWS-A questionnaire), and other possible confounding factors. Time spent in sedentary behavior, light physical activity, and moderate-to-vigorous physical activity will be used as three components in a composition reflecting individual MRBs. In linear multiple compositional regression analysis assessing the prospective association between obesity and MRBs, the 7-year follow-up composition of the three mentioned components represents the dependent variable. The 7-year changes in the percentage of body fat (body adiposity), baseline composition of MRBs, and parameters of the built environment represent regressors. DISCUSSION: This study will use an integrated time-use approach to explore causality from obesity to device-measured behaviors in older women. The design and respective analysis consider the compositional nature of MRBs data and the potential moderating effects of various factors. A comprehensive assessment of causality may help to develop multilevel interventional models that enhance physical activity in older adults.

Assessment of changes in somatic characteristics based on the level of physical activity in women who undertook weight reduction course.

OBJECTIVE: Obesity is a chronic disease in modern age and finding approach to the prevention, diagnosis and treatment of obesity has its place among the priorities of modern medicine and related fields. Important component in programmes to reduce overweight and obesity is regular physical activity (PA), which plays vital role in the comprehensive approach to the treatment of obesity. Primary objective of our study was to assess changes in somatic characteristics following eleven weeks of PA in overweight and obese women aged 30 to 60 years. METHODS: Our research sample consisted of 221 women who were classified according to the level of PA carried out, namely 1st, 2nd and 3rd category. STOB (STop OBesity) course participants underwent PA monitoring and diagnosis of the body composition, which is a modern multifaceted cognitive behavioural method. RESULTS: Younger highly active women (PA 3) achieved higher average differences in body fat than did women with the typical daily activity (PA 1), however, significant differences have not been found. Statistically significant differences in visceral fat between the 1st (PA 1) and 3rd PA category (PA 3) have been observed in older women. CONCLUSION: Given the significantly higher increase of fat-free mass percentage in older highly active women (PA 3), we may assess the course results positively. Our study demonstrated positive correlation between carrying out the recommended level of PA and its impact on the body composition's health risk indicators. Obese women should walk at least 10,000 steps per day to improve their health.

Associations of visceral fat area and physical activity levels with the risk of metabolic syndrome in postmenopausal women.

This study was aimed at the evaluation of relationship between visceral fat area (VFA) and physical activity (PA) with the metabolic syndrome (MetS) risk in the physically active postmenopausal women. A total of 85 attendants of the University of the Third Age (U3A) aged 62.8 ± 5.9 years (median time since menopause 11.8 y), participated in this study. VFA was assessed by bioimpedance method using InBody 720 analyzer. PA was assessed using the ActiGraph GT1 M accelerometer. Fasting levels of serum lipids (TG, HDL), serum glucose, waist circumference (WC) and blood pressure were measured to diagnose MetS according to NCEP-ATP III criteria. In 73 out of 85 participants the VFA exceeded the upper normal level of 100 cm2, however, in almost a half of this group (n = 36) with elevated VFA (139.5 ± 26.1 cm2 on average), only 2 out of 5 criteria for MetS diagnosis were met. Participants were physically active, making on average 10,919 ± 3435 steps/day. The risk of MetS occurrence in women with VFA > 100 cm2 was twelve times higher (OR 12.33; CI 95% [1.5; 99.8]) than in the group with VFA < 100 cm2. The participants from the group with the highest PA level (≥12,500 steps/day) were at almost 4 times lower risk for MetS, than their less active counterparts (OR 3.84; CI 95% [1.27;11.64]). Increased level of VFA is a strong risk factor for the MetS in postmenopausal women, however high level of regular PA above the threshold of 12,500 steps/day may substantially reduce it.

Fine motor skills of the hands in Polish and Czech female senior citizens from different backgrounds.

The aim of the present study was an in-depth analysis of fine motor skills of the hands in elderly women from different socio-cultural backgrounds. The research also included analysis of the associations of age with the variables assessing right- and left-hand motor skills and its effect on hand performance asymmetry. The study examined 486 women over the age of 60. The study measured dominant and non-dominant hand performance using the motor performance series test battery (aiming, line tracking, inserting pins, tapping) from the Vienna test system. The best results in the tests assessing coordinated hand movements were achieved by the group of elderly women attending a University of the Third Age in Poland. This may be the result of a larger variety of physical activity programs offered at this type of institution. However, due to the cross-sectional design of the study, additional research of a longitudinal nature needs to be performed using the same sample of individuals to draw any definitive conclusions. Additionally, a decrease in the differences between dominant and non-dominant hand function with age was observed.

Age-related changes in body composition in a sample of Czech women aged 18-89 years: a cross-sectional study.

BACKGROUND: The Czech Republic lacks body composition data for women. Therefore, the purpose of the study was to analyze body composition [body fat mass (BFM), fat-free mass (FFM), body fat percentage (%BFM) and visceral adipose tissue (VAT)] and to evaluate the changes that occur with aging in women aged 18-89 years. We also analyzed anthropometric characteristics of study participants and developed age-specific percentile curves for body composition parameters. METHODS: A cross-sectional, non-randomized study was conducted with a sample of 1,970 apparently healthy Czech women. Body composition was measured using a direct segmental multi-frequency bioelectrical impedance analysis (BSM-BIA). RESULTS: The mean BFM was 19.7 ± 8.9 kg, and BFM reached its peak in women over 70, at 27.6 ± 8.8 kg. There was a strong correlation between BFM and age (r = 0.61; r (2) = 0.37). Fifty percent of the women in the study had a BFM between 13.0 and 25.0 kg. The %BFM (r = 0.69; r (2) = 0.47) and VAT (r = 0.88; r (2) = 0.77) were also significantly associated with age. The reference range for %BFM was 22.0-35.6 % (25th-75th percentile). The mean FFM was 45.8 ± 5.5 kg, and FFM decreased with age (r = -0.27; r (2) = 0.07). CONCLUSIONS: The results presented in this study showed a statistically significant increase in BFM, %BFM and VFA as age increased, and the values reached their peak in women over 70. Even when FFM decreased slightly with age, body weight increased because of the increase in BFM.

[Evaluation of accuracy of body mass index in diagnosing of obesity in relation to body fat percentage in female aged 55-84 years]. / Posouzení objektivity hodnocení výskytu obezity na základe bodymass indexu vzhledem k procentuálnímu zastoupení telesného tuku u zen ve veku 55-84 let.

BACKGROUND: Currently, body mass index (BMI) is frequently used for evaluation of obesity prevalence. This weight to height index does not reflect variability and changes in body composition components, and therefore, the BMI prevalence data may significantly differ from those based on the body fat percentage (%BFM). For the above reason, the primary aim of the study was to determine the prevalence of overweight and obesity according to %BFM and relate these data to BMI categories in women aged 55-84 years. METHODS AND RESULTS: 446 females with an average age of 65.8 ± 6.4 years participated in this study. Body composition was measured using InBody 720. Our results have shown high prevalence of overweight and obesity in the study sample. Number of obese subjects increased with increasing age. We found the highest prevalence of obesity in females over 80 years. Evaluation of obesity according to BMI seems to be accurate in women with BMI > 30 kg/m2. We found only 1% of nonobese subjects (evaluated according to %BFM) in this BMI category. In contrast, there was found a large number of subjects with obesity (evaluated according to %BFM) among women in 18.5 to 24.9 kg/m2 and 25.0 to 29.9 kg/m2 BMI categories. CONCLUSIONS: The results have shown that obesity may be diagnosed in women with lower BMI (i.e., < 30 kg/m2). For this reason we recommend to evaluate the prevalence of obesity primarily from BFM% in this age group.

Postmenopausal obesity: 12,500 steps per day as a remedy? Relationships between body composition and daily steps in postmenopausal women.

INTRODUCTION: To verify relationships between physical activity (steps per day) and obesity (components of body composition) among postmenopausal women. MATERIAL AND METHODS: Physical activity (ActiGraph GT1M accelerometer; worn for 7 days) and obesity (body composition analyzer InBody 720) were assessed among 79 healthy postmenopausal women (age 63.25 ± 5.51 years; range: 51-81 years). In order to determine differences in body composition in women with different levels of physical activity, one-way analysis of covariance (ANCOVA) was conducted, with age of participants as a covariate. RESULTS: Significant intergroup differences in almost all analyzed components of the body composition (weight, body mass index, waist-hip ratio, visceral fat area, body fat mass and percent of body fat) were obtained. Highly active women (≥ 12,500 steps/day) had lower weight and adiposity parameters than those that represented low (< 7,500 steps/day) or somewhat active (7,500-9,999 steps/day) groups. Besides, a noteworthy difference between active (10,000-12,499 steps/day) and low active women was recorded. Noticeably, only in the most active group was the BMI within normal ranges. CONCLUSIONS: The higher physical activity, the lower obesity in postmenopausal women. The recommended 10,000 steps/day seems insufficient for this age group. Based on the obtained results, postmenopausal women should walk at least 12,500 steps per day to improve their health.

The level of neighborhood walkability in a place of residence and its effect on body composition in obese and overweight women.

A neighborhood environment allows defining typical features for physically active or inactive lifestyle. An accelerated pace of life and higher availability of an unhealthy lifestyle increase obesity rates. An analysis of body composition can be used as a predictor for assessment of current somatic conditions. The aim of the study was to determine the dependence of selected body composition parameters on neighborhood walkability in 167 women aged 20-60 years attending weight-loss programme called STOB-courses. A multifrequency bioimpedance analysis InBody 720 was used to determine the body composition of respondents. Further, ANEWS questionnaire was used to determine the level of neighborhood walkability. We divided the sample into two age groups (<40 years; >40 years) and into partial subgroups according to the neighborhood "level of walkability" (lower and higher level). Based on the assessment of body composition, it can be assumed more walkable neighborhood opportunities positively affect body composition. Body composition in older women is positively influenced if they lived in high walkable areas. In younger women we found only one indicator of body composition (body fat mass) influenced by neighborhood walkability. The relationship between health indicators of body composition and residential infrastructure might be useful in strategies aimed at maintaining and developing a healthy lifestyle within the community.

The Influence of Somatic Maturity on Anthropometrics and Body Composition in Youth Soccer Players.

The primary aim of this investigation was to compare players' anthropometric (AP) and body composition (BC) characteristics between distinct maturity bands (pre-PHV, circa-PHV, post-PHV) in youth elite soccer. This study considered 320 male soccer players (mean age 13.8 y). Participants were from U14 (n = 157) and U15 (n = 163) age categories. The Khamis-Roche method was applied to calculate the percentage of predicted adult height (PAH) at the time of assessment based on which the players were further divided into maturity bands (pre-PHV ≤ 87%, circa-PHV = 88-95%, post-PHV > 95%). The findings indicated that most of the players were in the circa-PHV stage at the time of investigation. Measurements included height and weight. The estimates of BC parameters were derived using bioelectrical impedance (BIA) analysis. These various AP and BC attributes displayed significant differences among the maturity bands (F = 139.344-7.925; p < 0.001; large effect sizes) except in body fat mass (BFM) (F = 2.998; p = 0.051; small effect size). The current somatic maturity stage of the athletes should be considered when evaluating BC results, otherwise there is a risk of misinterpretation.

The effect of calorie restriction on the anthropometric parameters, HOMA-IR index, and lipid profile of female office workers with overweight and obesity: a preliminary study.

OBJECTIVES: This study evaluates the effect of a 3-month calorie restriction (CR) without snacking on the anthropometric parameters, Homeostatic Model Assesment of Insulin Resistance (HOMA-IR), and lipid profiles of female office workers with overweight or obesity, whose physical activity was limited during the COVID-19 pandemic lockdown. MATERIAL AND METHODS: Forty-eight women aged 20-38 years (28.9±5.24) with low physical activity levels were divided into a non-snacking (NS) group (N = 21) and a snacking (S) group (N = 27) prior to the dietary intervention. Their daily energy intake during the intervention was lowered by 30% compared with the baseline level, and the proportion of polyunsaturated fatty acids and fiber in their diet was increased (to >30 g/day). The proportion of saturated fatty acids and simple carbohydrates was also reduced. The study participants were assessed at the baseline and post-intervention for anthropometric variables (body weight, body fat percentage BMI, waist circumference, hip circumference, waist-to-hip ratio) and the concentrations of insulin, total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). Moreover, the values for HOMA-IR, the atherogenic index of plasma (AIP), and the ratios of TC/HDL-C, TG/HDL-C, and LDL-C/HDL-C were calculated. RESULTS: All anthropometric parameter values obtained post-intervention were lower than the baseline in both groups. The serum insulin concentration and HOMA-IR decreased respectively by an average of 6% and 25% in the NS group and 37% and 45% in the S group. The lipid profiles of all participants improved significantly, with the LDL-C concentration showing a more promising trend in the S group (decrease by 27%) than in the NS group (17%). CONCLUSIONS: The study showed that CR improved the anthropometric parameters, HOMA-IR index, and lipid profiles of all participants. Int J Occup Med Environ Health. 2022;35(6):693-706.

Body Fat Mass, Percent Body Fat, Fat-Free Mass, and Skeletal Muscle Mass Reference Curves for Czech Children Aged 6-11 Years.

BACKGROUND: Negative lifestyle trends are reflected in overweight and obese children, in which their lack of physical activity results in decreased muscle mass. This study aimed to define age- and sex-specific reference curves for body fat mass (BFM), skeletal muscle mass (SMM), fat-free mass (FFM), and percent body fat (%BF) in Czech children. METHODS: Body composition was measured by segmental bioelectrical impedance (BIA, InBody 720). The research sample included 2093 children aged 6-11 years (1008 boys and 1085 girls). Only children whose parents provided informed consent were included. Statistical analysis was performed using SPSS v. 22. The statistical analysis was performed separately by age and sex. Anthropometric data were summarized as means and standard deviation. The percentile curves (P3, P10, P25, P50, P75, P90, and P97) of BFM, FFM, %BF, and SMM were calculated using the gamlss package in R 3.4.2 (R Foundation for Statistical Computing, Vienna, Austria). RESULTS: This study developed age- and gender-specific percentile curves of SMM, FFM, BFM, and %BF for Czech children aged 6-11 years. During childhood, BFM and %BF increased in boys, peaking at approximately 11 years of age. Girls displayed a different pattern of age-related changes in BFM and %BF compared to that in boys. These parameters gradually increased during childhood. This pattern was also observed for SMM and FFM in both sexes. CONCLUSIONS: The purpose of this study was to serve as a reference to improve methods to evaluate body composition in Czech children and for comparison with studies worldwide.

Device-Measured Physical Activity, Sedentary Behaviors, Built Environment, and Adiposity Gain in Older Women: A Seven-Year Prospective Study.

The search for determinants of adiposity gain in older women has become vitally important. This study aimed to (1) analyze the adiposity gain based on the participants' age and (2) determine the prospective associations of baseline intrapersonal, built environment, physical activity, and sedentary behavior variables with the adiposity gain in older women. This was a seven-year prospective study (baseline: 2009 to 2012; follow-up: 2016 to 2019) in older women (n = 178, baseline age = 62.8 ± 4.1 years). Baseline and follow-up adiposity (bioelectrical impedance) and baseline physical activity, sedentary behavior (accelerometers), and intrapersonal and built environment (Neighborhood Environment Walkability Scale questionnaire) variables were included. The body mass index (BMI) increment tended to be inversely associated with the women's age (p = 0.062). At follow-up, 48, 57, and 54% of the women had a relevant increase (d-Cohen > 0.2) in their BMI, percentage of body fat, and fat mass index, respectively. The women that spent ≥8 h/day being sedentary were 2.2 times (1.159 to 4.327 CI95%, p < 0.02) more likely to increase BMI (0.82 to 0.85 kg/m2) than non-sedentary women. No built environment variables were associated with seven-year adiposity gain (all ps > 0.05). A reduction in sedentary time should be promoted for adiposity gain prevention and health preservation in older women.

Prospective study on sedentary behaviour patterns and changes in body composition parameters in older women: A compositional and isotemporal substitution analysis.

BACKGROUND & AIMS: The aims of this study were to examine the prospective compositional associations between sedentary behaviour (SB) patterns and longitudinal changes in body composition parameters, and to use compositional isotemporal substitution modelling to analyse the longitudinal changes in body composition parameters associated with time reallocation from SB to physical activity (PA) in older women. METHODS: The study included women aged 60 years and older (n = 182) with valid data at baseline and at the subsequent 7-year follow-up. For both time points, the ActiGraph GT1M accelerometer was used for SB and PA assessments and multi-frequency bioimpedance analysis was used to assess the body composition parameters related to adiposity and muscle mass. Compositional regression models were used to analyse the associations between proportion of time spent in sedentary bouts of different duration and longitudinal changes in body composition parameters. A compositional isotemporal substitution model was created to estimate the differences in body composition parameters associated with one-to-one time reallocations between baseline SB and PA. RESULTS: A significant increase in fat mass index (ßilr1 = 0.61, 95% confidence interval [CI]: 0.18, 1.04) and visceral adipose tissue (ßilr1 = 6.01, 95% CI: 1.52, 10.5) was associated with a higher baseline proportion of time spent in long sedentary bouts (i.e. sedentary bout of ≥30 min). Reallocating 1 h/week and 3.5 h/week from the time spent in long sedentary bouts in favour of light PA was associated with a significant decrease in fat mass index by 0.78% (95% CI: 0.24, 1.32) and 3.13% (95% CI: 0.97, 5.29), respectively. No association was found for indicators of muscle mass. CONCLUSIONS: This study suggests that long-term adiposity status could be improved by increasing the proportion of time spent in light PA at the expense of time spent in prolonged SB. This finding may help in designing more effective and feasible interventions for the maintenance of healthy body composition in advanced age.

Effect of 12-Week Interventions Involving Nordic Walking Exercise and a Modified Diet on the Anthropometric Parameters and Blood Lipid Profiles in Overweight and Obese Ex-Coal Miners.

BACKGROUND: Overweight and obesity after retirement are likely to be caused by unhealthy eating habits and the energy intake exceeding the energy expenditure. OBJECTIVES: This study was designed to assess the effects of two 12-week interventions involving, respectively, either regular physical activity or a modified lower-calorie diet on the anthropometric parameters and blood lipid profiles in overweight and obese retired miners with lipid disorders. DESIGN: The study participants (n = 30, aged 58.7 ± 4.1 years, body height 174.8 ± 7.3 cm, body weight 96.6 ± 13.9 kg) were randomly assigned to 2 intervention groups: the Nordic walking group (NW), which exercised with intensity from 60 to 70% of participants' maximal heart rates for 1 h 3 times a week, and the modified diet group (MD). Modification of the diet consisted of reducing the daily energy intake by 30%, increasing the dietary content of mono- and polyunsaturated fatty acids and dietary fiber, and reducing the proportion of saturated fatty acids. The variables assessed at baseline and after 6 and 12 weeks were: anthropometric parameters (body weight, fat mass content [FM], fat percentage [BF], BMI, waist circumference [WC], hip circumference [HC], and waist-to-hip ratio [WHR]) and blood lipid indicators (total cholesterol [TC], triglycerides [TG], low density lipoprotein cholesterol [LDL-C], and high density lip-oprotein cholesterol [HDL-C]). RESULTS: The body weight of the participants in the NW was lower at week 12 by an average of 5 kg, BMI by 6%, FB by 19%, FM by 15%, WC by 8%, HC by 6%, and WHR by 3%. In the MD, the respective decreases were 8 kg and 8, 25, 20, 6, 2, and 7%. In the MD, the postintervention concentrations of TC and TG were within the reference range. CONCLUSION: Both 12-week interventions improved the anthropometric parameters and blood lipid profiles of retired heavy manual workers, with the improvements being more pronounced in the dieting group.

Evaluation of Plantar Pressure Distribution in Relationship to Body Mass Index in Czech Women During Walking.

BACKGROUND: Excessive body weight seems to be a risk factor for foot loading. We sought to investigate the effect of different body mass index (BMI) levels on plantar pressure distribution during walking. METHODS: In total, 163 women aged 45 to 65 years (mean ± SD: age, 57.4 ± 5.3 years; BMI, 27.0 ± 5.3) participated in the study. The women were divided, on the basis of BMI, into a normal-weight, overweight, or obese group. The study used the four following plantar pressure parameters (PPPs): contact percentage, absolute pressure impulse, relative pressure impulse, and absolute peak pressure, which were recorded in ten foot regions using a pressure measurement system. RESULTS: The normal-weight group, compared with the overweight and obese groups, had significantly lower absolute PPP values. In the hallux, second through fifth metatarsals, midfoot, and heel regions, we observed significant between-group differences in the two absolute PPPs (peak pressure and pressure impulse) (P < .001). Between-group differences in the relative PPPs were found in the fourth metatarsal, midfoot, and medial heel (relative impulse) and in the second metatarsal (contact percentage) (P < .001). CONCLUSIONS: Higher BMI values correspond to a higher load on the foot during walking in women. The relative foot load in obese women is characterized by a pressure increase in the lateral forefoot and midfoot and by a pressure decrease in the medial heel.

Physical activity, body composition and general health status of physically active students of the University of the Third Age (U3A).

OBJECTIVE: To evaluate general health status of a group of older adults, physically active students of the University of the Third Age (U3A), based on results of biochemical analyses of blood, assessment of their physical activity (PA) level, body composition and cognitive function with respect to age and sex. METHODS: A total of 104 students (85 women and 19 men, aged 63.7±6.6 y) of the U3A's located in the Upper Silesia region of Poland volunteered to participate in this study. A habitual PA level and body composition were objectively assessed by using ActiGraph GT1M and InBody 720, respectively. Serum lipid profile and glucose metabolism markers were measured for assessment of cardiovascular disease risk factors. Moreover, subjects' cognitive functions were tested. RESULTS: Most of the study participants reached the daily step goal of 10,000 steps and thus fulfilled the ACSM recommendations for the quantity and quality of cardiorespiratory exercise. Highly negative correlations between the number of steps per day and body adiposity markers, serum insulin and HOMA-IR confirmed that vigorous physical activity at the recommended level was associated with better body composition and lower levels of risk markers of coronary heart disease and diabetes. Most of the U3A students were characterized by a favorable lipid profile, prevalence of normal blood pressure, low rates of HOMA-estimated insulin resistance and normal cognitive function. CONCLUSION: Adherence to ACSM recommendations is associated with beneficial changes in risk factors related to cardiovascular disease.