Detalhe da pesquisa
1.
A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Nature
; 603(7900): 328-334, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197632
2.
Publisher Correction: A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Nature
; 604(7905): E13, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332336
3.
A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
J Biol Chem
; 295(52): 18379-18389, 2020 12 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33122192
4.
Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth.
J Virol
; 94(6)2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31826999
5.
biAb Mediated Restoration of the Linkage between Dystroglycan and Laminin-211 as a Therapeutic Approach for α-Dystroglycanopathies.
Mol Ther
; 28(2): 664-676, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31843448
6.
Site-specific PEGylation of human thyroid stimulating hormone to prolong duration of action.
Bioconjug Chem
; 24(3): 408-18, 2013 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23350694
7.
Clinical poisoning events involving yunaconitine may be highly correlated with metabolism-based interactions: A critical role of CYP3A4.
Food Chem Toxicol
; 179: 113989, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37619830
8.
Salvianolic acid F suppresses KRAS-dependent lung cancer cell growth through the PI3K/AKT signaling pathway.
Phytomedicine
; 121: 155093, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783131
9.
Neoline, fuziline, songorine and 10-OH mesaconitine are potential quality markers of Fuzi: In vitro and in vivo explorations as well as pharmacokinetics, efficacy and toxicity evaluations.
J Ethnopharmacol
; 303: 115879, 2023 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36370966
10.
Insight into the mechanism of Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea based on regulating the gut microbiota and inhibiting Gut ß-GUS.
Phytomedicine
; 120: 155040, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37683587
11.
XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.
J Immunother Cancer
; 11(12)2023 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38164757
12.
X-ray and biochemical analysis of N370S mutant human acid ß-glucosidase.
J Biol Chem
; 286(1): 299-308, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20980263
13.
High-affinity VEGF antagonists by oligomerization of a minimal sequence VEGF-binding domain.
Bioconjug Chem
; 23(12): 2354-64, 2012 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23176598
14.
Combined inhibition of ACK1 and AKT shows potential toward targeted therapy against KRAS-mutant non-small-cell lung cancer.
Bosn J Basic Med Sci
; 21(2): 198-207, 2021 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32530390
15.
Site-Specific Antibody Conjugation to Engineered Double Cysteine Residues.
Pharmaceuticals (Basel)
; 14(7)2021 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34358098
16.
Pharmacokinetics of novel Fc-engineered monoclonal and multispecific antibodies in cynomolgus monkeys and humanized FcRn transgenic mouse models.
MAbs
; 12(1): 1829337, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33079615
17.
Engineered Fc-glycosylation switch to eliminate antibody effector function.
MAbs
; 12(1): 1814583, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32892677
18.
Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation.
Nat Cancer
; 1(1): 86-98, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35121834
19.
The Mechanistic Impact of N-Glycosylation on Stability, Pharmacokinetics, and Immunogenicity of Therapeutic Proteins.
J Pharm Sci
; 108(4): 1366-1377, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30471292
20.
Antibody Fc engineering for enhanced neonatal Fc receptor binding and prolonged circulation half-life.
MAbs
; 11(7): 1276-1288, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31216930