Detalhe da pesquisa
1.
Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
Blood
; 139(14): 2107-2118, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35090172
2.
Krüppel-like factor 3 (KLF3) suppresses NF-κB-driven inflammation in mice.
J Biol Chem
; 295(18): 6080-6091, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32213596
3.
Wake-up Sleepy Gene: Reactivating Fetal Globin for ß-Hemoglobinopathies.
Trends Genet
; 34(12): 927-940, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30287096
4.
A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site.
Blood
; 133(8): 852-856, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30617196
5.
Characterization of Glucose Transporter 6 in Lipopolysaccharide-Induced Bone Marrow-Derived Macrophage Function.
J Immunol
; 202(6): 1826-1832, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700586
6.
Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act.
Bioessays
; 41(8): e1900041, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31245868
7.
EoTHINophils: Eosinophils as key players in adipose tissue homeostasis.
Clin Exp Pharmacol Physiol
; 47(8): 1495-1505, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32163614
8.
Defining Eosinophil Function in Adiposity and Weight Loss.
Bioessays
; 40(10): e1800098, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30132936
9.
KLF1 drives the expression of fetal hemoglobin in British HPFH.
Blood
; 130(6): 803-807, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28659276
10.
METTL21B Is a Novel Human Lysine Methyltransferase of Translation Elongation Factor 1A: Discovery by CRISPR/Cas9 Knockout.
Mol Cell Proteomics
; 16(12): 2229-2242, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28663172
11.
Analysis of the ACTN3 heterozygous genotype suggests that α-actinin-3 controls sarcomeric composition and muscle function in a dose-dependent fashion.
Hum Mol Genet
; 25(5): 866-77, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26681802
12.
Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain.
Nucleic Acids Res
; 44(7): 3118-30, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673701
13.
Altered Ca2+ kinetics associated with α-actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution.
PLoS Genet
; 11(2): e1004862, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25590636
14.
Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3).
J Biol Chem
; 291(31): 16048-58, 2016 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226561
15.
How does α-actinin-3 deficiency alter muscle function? Mechanistic insights into ACTN3, the 'gene for speed'.
Biochim Biophys Acta
; 1863(4): 686-93, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26802899
16.
Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity.
J Biol Chem
; 290(13): 8591-605, 2015 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25659434
17.
NF1 is a critical regulator of muscle development and metabolism.
Hum Mol Genet
; 23(5): 1250-9, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24163128
18.
Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells.
BMC Mol Biol
; 15: 8, 2014 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24885809
19.
Regulation of host metabolic health by parasitic helminths.
Trends Parasitol
; 40(5): 386-400, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38609741
20.
Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling.
Hum Mol Genet
; 20(15): 2914-27, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21536590