Detalhe da pesquisa
1.
An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms.
Cell
; 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38876107
2.
Clinical presentation of early syphilis and genomic sequences of Treponema pallidum strains in patient specimens and isolates obtained by rabbit inoculation.
J Infect Dis
; 2024 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38884588
3.
Host-specific functional compartmentalization within the oligopeptide transporter during the Borrelia burgdorferi enzootic cycle.
PLoS Pathog
; 17(1): e1009180, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33428666
4.
PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi.
PLoS Pathog
; 17(7): e1009725, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34265024
5.
Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis.
PLoS Pathog
; 16(9): e1008871, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32936831
6.
Analysis of Treponema pallidum Strains From China Using Improved Methods for Whole-Genome Sequencing From Primary Syphilis Chancres.
J Infect Dis
; 223(5): 848-853, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32710788
7.
Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine.
J Bacteriol
; 203(15): e0008221, 2021 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972353
8.
Lyme Disease in Humans.
Curr Issues Mol Biol
; 42: 333-384, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33303701
9.
Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation.
BMC Immunol
; 22(1): 32, 2021 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34000990
10.
Outcomes From Re-Treatment and Cerebrospinal Fluid Analyses in Patients With Syphilis Who Had Serological Nonresponse or Lack of Seroreversion After Initial Therapy.
Sex Transm Dis
; 48(6): 443-450, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33093287
11.
The Treponema pallidum Outer Membrane.
Curr Top Microbiol Immunol
; 415: 1-38, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28849315
12.
Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL ß-BARREL DOMAIN.
J Biol Chem
; 290(19): 12313-31, 2015 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25805501
13.
Stage-specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation.
Mol Microbiol
; 95(3): 509-38, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25425211
14.
Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes.
BMC Microbiol
; 16(1): 141, 2016 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27400788
15.
A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326.
J Bacteriol
; 197(11): 1906-20, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25825429
16.
Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding.
J Struct Biol
; 192(1): 48-58, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26321039
17.
Cyclic di-GMP modulates gene expression in Lyme disease spirochetes at the tick-mammal interface to promote spirochete survival during the blood meal and tick-to-mammal transmission.
Infect Immun
; 83(8): 3043-60, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25987708
18.
HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete.
PLoS Pathog
; 9(12): e1003841, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24367266
19.
A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy.
BMC Infect Dis
; 15: 479, 2015 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26511465
20.
The heterogeneous motility of the Lyme disease spirochete in gelatin mimics dissemination through tissue.
Proc Natl Acad Sci U S A
; 109(8): 3059-64, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22315410