Detalhe da pesquisa
1.
A phase Ib trial of mivavotinib (TAK-659), a dual SYK/FLT3 inhibitor, in patients with relapsed/refractory acute myeloid leukemia.
Haematologica
; 108(3): 705-716, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36226495
2.
CCRL2 affects the sensitivity of myelodysplastic syndrome and secondary acute myeloid leukemia cells to azacitidine.
Haematologica
; 108(7): 1886-1899, 2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36519323
3.
A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia.
Haematologica
; 106(4): 1022-1033, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33504139
4.
Crenolanib is a potent inhibitor of FLT3 with activity against resistance-conferring point mutants.
Blood
; 123(1): 94-100, 2014 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24227820
5.
Phase 2 study of azacytidine plus sorafenib in patients with acute myeloid leukemia and FLT-3 internal tandem duplication mutation.
Blood
; 121(23): 4655-62, 2013 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23613521
6.
Phase I/II trial of the combination of midostaurin (PKC412) and 5-azacytidine for patients with acute myeloid leukemia and myelodysplastic syndrome.
Am J Hematol
; 90(4): 276-81, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25530214
7.
Phase I trial of maintenance sorafenib after allogeneic hematopoietic stem cell transplantation for fms-like tyrosine kinase 3 internal tandem duplication acute myeloid leukemia.
Biol Blood Marrow Transplant
; 20(12): 2042-8, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25239228
8.
Preclinical studies of gilteritinib, a next-generation FLT3 inhibitor.
Blood
; 129(2): 257-260, 2017 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27908881
9.
Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML.
Blood
; 120(20): 4205-14, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23012328
10.
A phase 1 study of the irreversible FLT3 inhibitor FF-10101 in relapsed or refractory acute myeloid leukemia.
Blood Adv
; 8(10): 2527-2535, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38502195
11.
FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML.
Blood
; 115(7): 1425-32, 2010 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20007803
12.
The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia.
Sci Adv
; 8(7): eabl8952, 2022 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35179961
13.
Midostaurin after allogeneic stem cell transplant in patients with FLT3-internal tandem duplication-positive acute myeloid leukemia.
Bone Marrow Transplant
; 56(5): 1180-1189, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33288862
14.
Regulation of renal proximal tubule Na-K-ATPase by prostaglandins.
Am J Physiol Renal Physiol
; 298(5): F1222-34, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20130120
15.
Renal proximal tubule Na,K-ATPase is controlled by CREB-regulated transcriptional coactivators as well as salt-inducible kinase 1.
Cell Signal
; 27(12): 2568-78, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26432356
16.
A potential therapeutic target for FLT3-ITD AML: PIM1 kinase.
Leuk Res
; 36(2): 224-31, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21802138
17.
Evidence for post-transcriptional regulation of Na,K-ATPase by prostaglandin E1.
Biochem Biophys Res Commun
; 345(2): 739-45, 2006 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-16701566
18.
Identification of a prostaglandin-responsive element in the Na,K-ATPase beta 1 promoter that is regulated by cAMP and Ca2+. Evidence for an interactive role of cAMP regulatory element-binding protein and Sp1.
J Biol Chem
; 280(1): 334-46, 2005 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15485816
19.
Regulation of the Na,K-ATPase in MDCK cells by prostaglandin E1: a role for calcium as well as cAMP.
Exp Cell Res
; 299(1): 1-14, 2004 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15302568
20.
Clonal analysis of immortalized renal proximal tubule cells: Na(+)/glucose cotransport system levels are maintained despite a decline in transport function.
Exp Cell Res
; 281(2): 205-12, 2002 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12460651