Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Extremely potent human monoclonal antibodies from COVID-19 convalescent patients.

Andreano, Emanuele; Nicastri, Emanuele; Paciello, Ida; Pileri, Piero; Manganaro, Noemi; Piccini, Giulia; Manenti, Alessandro; Pantano, Elisa; Kabanova, Anna; Troisi, Marco; Vacca, Fabiola; Cardamone, Dario; De Santi, Concetta; Torres, Jonathan L; Ozorowski, Gabriel; Benincasa, Linda; Jang, Hyesun; Di Genova, Cecilia; Depau, Lorenzo; Brunetti, Jlenia; Agrati, Chiara; Capobianchi, Maria Rosaria; Castilletti, Concetta; Emiliozzi, Arianna; Fabbiani, Massimiliano; Montagnani, Francesca; Bracci, Luisa; Sautto, Giuseppe; Ross, Ted M; Montomoli, Emanuele; Temperton, Nigel; Ward, Andrew B; Sala, Claudia; Ippolito, Giuseppe; Rappuoli, Rino.

Cell ; 184(7): 1821-1835.e16, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-33667349

2.

Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.

Walls, Alexandra C; Miranda, Marcos C; Schäfer, Alexandra; Pham, Minh N; Greaney, Allison; Arunachalam, Prabhu S; Navarro, Mary-Jane; Tortorici, M Alejandra; Rogers, Kenneth; O'Connor, Megan A; Shirreff, Lisa; Ferrell, Douglas E; Bowen, John; Brunette, Natalie; Kepl, Elizabeth; Zepeda, Samantha K; Starr, Tyler; Hsieh, Ching-Lin; Fiala, Brooke; Wrenn, Samuel; Pettie, Deleah; Sydeman, Claire; Sprouse, Kaitlin R; Johnson, Max; Blackstone, Alyssa; Ravichandran, Rashmi; Ogohara, Cassandra; Carter, Lauren; Tilles, Sasha W; Rappuoli, Rino; Leist, Sarah R; Martinez, David R; Clark, Matthew; Tisch, Roland; O'Hagan, Derek T; Van Der Most, Robbert; Van Voorhis, Wesley C; Corti, Davide; McLellan, Jason S; Kleanthous, Harry; Sheahan, Timothy P; Smith, Kelly D; Fuller, Deborah H; Villinger, Francois; Bloom, Jesse; Pulendran, Bali; Baric, Ralph S; King, Neil P; Veesler, David.

Cell ; 184(21): 5432-5447.e16, 2021 10 14.

Artigo em Inglês | MEDLINE | ID: mdl-34619077

3.

Timeline: Vaccines.

Rappuoli, Rino.

Cell ; 183(2): 552, 2020 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-33064991

4.

Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules.

Stravalaci, Matteo; Pagani, Isabel; Paraboschi, Elvezia Maria; Pedotti, Mattia; Doni, Andrea; Scavello, Francesco; Mapelli, Sarah N; Sironi, Marina; Perucchini, Chiara; Varani, Luca; Matkovic, Milos; Cavalli, Andrea; Cesana, Daniela; Gallina, Pierangela; Pedemonte, Nicoletta; Capurro, Valeria; Clementi, Nicola; Mancini, Nicasio; Invernizzi, Pietro; Bayarri-Olmos, Rafael; Garred, Peter; Rappuoli, Rino; Duga, Stefano; Bottazzi, Barbara; Uguccioni, Mariagrazia; Asselta, Rosanna; Vicenzi, Elisa; Mantovani, Alberto; Garlanda, Cecilia.

Nat Immunol ; 23(2): 275-286, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-35102342

5.

Self-Assembling Nanoparticles Usher in a New Era of Vaccine Design.

Rappuoli, Rino; Serruto, Davide.

Cell ; 176(6): 1245-1247, 2019 03 07.

Artigo em Inglês | MEDLINE | ID: mdl-30849370

6.

Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19.

Asselta, Rosanna; Paraboschi, Elvezia Maria; Stravalaci, Matteo; Invernizzi, Pietro; Bonfanti, Paolo; Biondi, Andrea; Pagani, Isabel; Pedotti, Mattia; Doni, Andrea; Scavello, Francesco; Mapelli, Sarah N; Sironi, Marina; Perucchini, Chiara; Varani, Luca; Matkovic, Milos; Cavalli, Andrea; Cesana, Daniela; Gallina, Pierangela; Pedemonte, Nicoletta; Capurro, Valeria; Clementi, Nicola; Mancini, Nicasio; Bayarri-Olmos, Rafael; Garred, Peter; Rappuoli, Rino; Duga, Stefano; Bottazzi, Barbara; Uguccioni, Mariagrazia; Vicenzi, Elisa; Mantovani, Alberto; Garlanda, Cecilia.

Nat Immunol ; 23(6): 865-867, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35624207

7.

Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants.

Andreano, Emanuele; Paciello, Ida; Piccini, Giulia; Manganaro, Noemi; Pileri, Piero; Hyseni, Inesa; Leonardi, Margherita; Pantano, Elisa; Abbiento, Valentina; Benincasa, Linda; Giglioli, Ginevra; De Santi, Concetta; Fabbiani, Massimiliano; Rancan, Ilaria; Tumbarello, Mario; Montagnani, Francesca; Sala, Claudia; Montomoli, Emanuele; Rappuoli, Rino.

Nature ; 600(7889): 530-535, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34670266

8.

Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.

Arunachalam, Prabhu S; Walls, Alexandra C; Golden, Nadia; Atyeo, Caroline; Fischinger, Stephanie; Li, Chunfeng; Aye, Pyone; Navarro, Mary Jane; Lai, Lilin; Edara, Venkata Viswanadh; Röltgen, Katharina; Rogers, Kenneth; Shirreff, Lisa; Ferrell, Douglas E; Wrenn, Samuel; Pettie, Deleah; Kraft, John C; Miranda, Marcos C; Kepl, Elizabeth; Sydeman, Claire; Brunette, Natalie; Murphy, Michael; Fiala, Brooke; Carter, Lauren; White, Alexander G; Trisal, Meera; Hsieh, Ching-Lin; Russell-Lodrigue, Kasi; Monjure, Christopher; Dufour, Jason; Spencer, Skye; Doyle-Meyers, Lara; Bohm, Rudolph P; Maness, Nicholas J; Roy, Chad; Plante, Jessica A; Plante, Kenneth S; Zhu, Alex; Gorman, Matthew J; Shin, Sally; Shen, Xiaoying; Fontenot, Jane; Gupta, Shakti; O'Hagan, Derek T; Van Der Most, Robbert; Rappuoli, Rino; Coffman, Robert L; Novack, David; McLellan, Jason S; Subramaniam, Shankar.

Nature ; 594(7862): 253-258, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33873199

9.

High-resolution map of the Fc functions mediated by COVID-19-neutralizing antibodies.

Paciello, Ida; Maccari, Giuseppe; Pantano, Elisa; Andreano, Emanuele; Rappuoli, Rino.

Proc Natl Acad Sci U S A ; 121(3): e2314730121, 2024 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-38198525

10.

Emerging roles of SARS-CoV-2 Spike-ACE2 in immune evasion and pathogenesis.

Baldari, Cosima T; Onnis, Anna; Andreano, Emanuele; Del Giudice, Giuseppe; Rappuoli, Rino.

Trends Immunol ; 44(6): 424-434, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37137805

11.

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.

Torres, Jonathan L; Ozorowski, Gabriel; Andreano, Emanuele; Liu, Hejun; Copps, Jeffrey; Piccini, Giulia; Donnici, Lorena; Conti, Matteo; Planchais, Cyril; Planas, Delphine; Manganaro, Noemi; Pantano, Elisa; Paciello, Ida; Pileri, Piero; Bruel, Timothée; Montomoli, Emanuele; Mouquet, Hugo; Schwartz, Olivier; Sala, Claudia; De Francesco, Raffaele; Wilson, Ian A; Rappuoli, Rino; Ward, Andrew B.

Proc Natl Acad Sci U S A ; 119(20): e2120976119, 2022 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-35549549

12.

Immunology and Technology of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines.

Pecetta, Simone; Kratochvil, Sven; Kato, Yu; Vadivelu, Kumaran; Rappuoli, Rino.

Pharmacol Rev ; 74(1): 313-339, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-35101964

13.

Transforming vaccine development.

Black, Steve; Bloom, David E; Kaslow, David C; Pecetta, Simone; Rappuoli, Rino.

Semin Immunol ; 50: 101413, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-33127296

14.

Vaccinology in the post-COVID-19 era.

Rappuoli, Rino; De Gregorio, Ennio; Del Giudice, Giuseppe; Phogat, Sanjay; Pecetta, Simone; Pizza, Mariagrazia; Hanon, Emmanuel.

Proc Natl Acad Sci U S A ; 118(3)2021 01 19.

Artigo em Inglês | MEDLINE | ID: mdl-33431690

15.

SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma.

Andreano, Emanuele; Piccini, Giulia; Licastro, Danilo; Casalino, Lorenzo; Johnson, Nicole V; Paciello, Ida; Dal Monego, Simeone; Pantano, Elisa; Manganaro, Noemi; Manenti, Alessandro; Manna, Rachele; Casa, Elisa; Hyseni, Inesa; Benincasa, Linda; Montomoli, Emanuele; Amaro, Rommie E; McLellan, Jason S; Rappuoli, Rino.

Proc Natl Acad Sci U S A ; 118(36)2021 09 07.

Artigo em Inglês | MEDLINE | ID: mdl-34417349

16.

Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action.

Maruggi, Giulietta; Ulmer, Jeffrey B; Rappuoli, Rino; Yu, Dong.

Curr Top Microbiol Immunol ; 440: 31-70, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-33861374

17.

Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide.

Henriques, Pedro; Dello Iacono, Lucia; Gimeno, Ana; Biolchi, Alessia; Romano, Maria Rosaria; Arda, Ana; Bernardes, GonÒ«alo J L; Jimenez-Barbero, Jesus; Berti, Francesco; Rappuoli, Rino; Adamo, Roberto.

Proc Natl Acad Sci U S A ; 117(47): 29795-29802, 2020 11 24.

Artigo em Inglês | MEDLINE | ID: mdl-33158970

18.

Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM₁₉₇ conjugate vaccine.

Micoli, Francesca; Bjarnarson, Stefania P; Arcuri, Melissa; Aradottir Pind, Audur Anna; Magnusdottir, Gudbjorg J; Necchi, Francesca; Di Benedetto, Roberta; Carducci, Martina; Schiavo, Fabiola; Giannelli, Carlo; Pisoni, Ivan; Martin, Laura B; Del Giudice, Giuseppe; MacLennan, Calman A; Rappuoli, Rino; Jonsdottir, Ingileif; Saul, Allan.

Proc Natl Acad Sci U S A ; 117(39): 24443-24449, 2020 09 29.

Artigo em Inglês | MEDLINE | ID: mdl-32900928

19.

4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp.

Veggi, Daniele; Bianchi, Federica; Santini, Laura; Lo Surdo, Paola; Chesterman, Chelsy C; Pansegrau, Werner; Bechi, Nicoletta; Huang, Ying; Masignani, Vega; Pizza, Mariagrazia; Rappuoli, Rino; Bottomley, Matthew J; Cozzi, Roberta; Maione, Domenico.

PLoS Pathog ; 16(10): e1008882, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-33007046

20.

Vaccine sprint predicted a decade ago.