COLAEVA: Visual Analytics and Data Mining Web-Based Tool for Virtual Coaching of Older Adult Populations.

The global population is aging in an unprecedented manner and the challenges for improving the lives of older adults are currently both a strong priority in the political and healthcare arena. In this sense, preventive measures and telemedicine have the potential to play an important role in improving the number of healthy years older adults may experience and virtual coaching is a promising research area to support this process. This paper presents COLAEVA, an interactive web application for older adult population clustering and evolution analysis. Its objective is to support caregivers in the design, validation and refinement of coaching plans adapted to specific population groups. COLAEVA enables coaching caregivers to interactively group similar older adults based on preliminary assessment data, using AI features, and to evaluate the influence of coaching plans once the final assessment is carried out for a baseline comparison. To evaluate COLAEVA, a usability test was carried out with 9 test participants obtaining an average SUS score of 71.1. Moreover, COLAEVA is available online to use and explore.

PDSS: A Pharmacological Decision Support System for Diabetics Patients with COVID-19.

With the advent of SARS-CoV-2, several studies have shown that there is a higher mortality rate in patients with diabetes and, in some cases, it is one of the side effects of overcoming the disease. However, there is no clinical decision support tool or specific treatment protocols for these patients. To tackle this issue, in this paper we present a Pharmacological Decision Support System (PDSS) providing intelligent decision support for COVID-19 diabetic patient treatment selection, based on an analysis of risk factors with data from electronic medical records using Cox regression. The goal of the system is to create real world evidence including the ability to continuously learn to improve clinical practice and outcomes of diabetic patients with COVID-19.

Unsupervised domain adaptation for the segmentation of breast tissue in mammography images.

BACKGROUND AND OBJECTIVE: Breast density refers to the proportion of glandular and fatty tissue in the breast and is recognized as a useful factor assessing breast cancer risk. Moreover, the segmentation of the high-density glandular tissue from mammograms can assist medical professionals visualizing and localizing areas that may require additional attention. Developing robust methods to segment breast tissues is challenging due to the variations in mammographic acquisition systems and protocols. Deep learning methods are effective in medical image segmentation but they often require large quantities of labelled data. Unsupervised domain adaptation is an area of research that employs unlabelled data to improve model performance on variations of samples derived from different sources. METHODS: First, a U-Net architecture was used to perform segmentation of the fatty and glandular tissues with labelled data from a single acquisition device. Then, adversarial-based unsupervised domain adaptation methods were used to incorporate single unlabelled target domains, consisting of images from a different machine, into the training. Finally, the domain adaptation model was extended to include multiple unlabelled target domains by combining a reconstruction task with adversarial training. RESULTS: The adversarial training was found to improve the generalization of the initial model on new domain data, demonstrating clearly improved segmentation of the breast tissues. For training with multiple unlabelled domains, combining a reconstruction task with adversarial training improved the stability of the training and yielded adequate segmentation results across all domains with a single model. CONCLUSIONS: Results demonstrated the potential for adversarial-based domain adaptation with U-Net architectures for segmentation of breast tissue in mammograms coming from several devices and demonstrated that domain-adapted models could achieve a similar agreement with manual segmentations. It has also been found that combining adversarial and reconstruction-based methods can provide a simple and effective solution for training with multiple unlabelled target domains.