Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.

Neftel, Cyril; Laffy, Julie; Filbin, Mariella G; Hara, Toshiro; Shore, Marni E; Rahme, Gilbert J; Richman, Alyssa R; Silverbush, Dana; Shaw, McKenzie L; Hebert, Christine M; Dewitt, John; Gritsch, Simon; Perez, Elizabeth M; Gonzalez Castro, L Nicolas; Lan, Xiaoyang; Druck, Nicholas; Rodman, Christopher; Dionne, Danielle; Kaplan, Alexander; Bertalan, Mia S; Small, Julia; Pelton, Kristine; Becker, Sarah; Bonal, Dennis; Nguyen, Quang-De; Servis, Rachel L; Fung, Jeremy M; Mylvaganam, Ravindra; Mayr, Lisa; Gojo, Johannes; Haberler, Christine; Geyeregger, Rene; Czech, Thomas; Slavc, Irene; Nahed, Brian V; Curry, William T; Carter, Bob S; Wakimoto, Hiroaki; Brastianos, Priscilla K; Batchelor, Tracy T; Stemmer-Rachamimov, Anat; Martinez-Lage, Maria; Frosch, Matthew P; Stamenkovic, Ivan; Riggi, Nicolo; Rheinbay, Esther; Monje, Michelle; Rozenblatt-Rosen, Orit; Cahill, Daniel P; Patel, Anoop P.

Cell ; 178(4): 835-849.e21, 2019 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-31327527

2.

Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain.

Boulay, Gaylor; Sandoval, Gabriel J; Riggi, Nicolo; Iyer, Sowmya; Buisson, Rémi; Naigles, Beverly; Awad, Mary E; Rengarajan, Shruthi; Volorio, Angela; McBride, Matthew J; Broye, Liliane C; Zou, Lee; Stamenkovic, Ivan; Kadoch, Cigall; Rivera, Miguel N.

Cell ; 171(1): 163-178.e19, 2017 Sep 21.

Artigo em Inglês | MEDLINE | ID: mdl-28844694

3.

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells.

Suvà, Mario L; Rheinbay, Esther; Gillespie, Shawn M; Patel, Anoop P; Wakimoto, Hiroaki; Rabkin, Samuel D; Riggi, Nicolo; Chi, Andrew S; Cahill, Daniel P; Nahed, Brian V; Curry, William T; Martuza, Robert L; Rivera, Miguel N; Rossetti, Nikki; Kasif, Simon; Beik, Samantha; Kadri, Sabah; Tirosh, Itay; Wortman, Ivo; Shalek, Alex K; Rozenblatt-Rosen, Orit; Regev, Aviv; Louis, David N; Bernstein, Bradley E.

Cell ; 157(3): 580-94, 2014 Apr 24.

Artigo em Inglês | MEDLINE | ID: mdl-24726434

4.

Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies.

Boulay, Gaylor; Volorio, Angela; Iyer, Sowmya; Broye, Liliane C; Stamenkovic, Ivan; Riggi, Nicolo; Rivera, Miguel N.

Genes Dev ; 32(15-16): 1008-1019, 2018 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-30042132

5.

Bioengineered 'mini-colons' shed light on cancer progression.

Riggi, Nicolò; de Sousa E Melo, Felipe.

Nature ; 629(8011): 292-293, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38658717

6.

IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer.

Degrauwe, Nils; Suvà, Mario-Luca; Janiszewska, Michalina; Riggi, Nicolo; Stamenkovic, Ivan.

Genes Dev ; 30(22): 2459-2474, 2016 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-27940961

7.

Genomic and transcriptomic landscape of conjunctival melanoma.

Cisarova, Katarina; Folcher, Marc; El Zaoui, Ikram; Pescini-Gobert, Rosanna; Peter, Virginie G; Royer-Bertrand, Beryl; Zografos, Leonidas; Schalenbourg, Ann; Nicolas, Michael; Rimoldi, Donata; Leyvraz, Serge; Riggi, Nicolò; Moulin, Alexandre P; Rivolta, Carlo.

PLoS Genet ; 16(12): e1009201, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33383577

8.

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.

Tirosh, Itay; Venteicher, Andrew S; Hebert, Christine; Escalante, Leah E; Patel, Anoop P; Yizhak, Keren; Fisher, Jonathan M; Rodman, Christopher; Mount, Christopher; Filbin, Mariella G; Neftel, Cyril; Desai, Niyati; Nyman, Jackson; Izar, Benjamin; Luo, Christina C; Francis, Joshua M; Patel, Aanand A; Onozato, Maristela L; Riggi, Nicolo; Livak, Kenneth J; Gennert, Dave; Satija, Rahul; Nahed, Brian V; Curry, William T; Martuza, Robert L; Mylvaganam, Ravindra; Iafrate, A John; Frosch, Matthew P; Golub, Todd R; Rivera, Miguel N; Getz, Gad; Rozenblatt-Rosen, Orit; Cahill, Daniel P; Monje, Michelle; Bernstein, Bradley E; Louis, David N; Regev, Aviv; Suvà, Mario L.

Nature ; 539(7628): 309-313, 2016 11 10.

Artigo em Inglês | MEDLINE | ID: mdl-27806376

9.

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells.

Janiszewska, Michalina; Suvà, Mario L; Riggi, Nicolo; Houtkooper, Riekelt H; Auwerx, Johan; Clément-Schatlo, Virginie; Radovanovic, Ivan; Rheinbay, Esther; Provero, Paolo; Stamenkovic, Ivan.

Genes Dev ; 26(17): 1926-44, 2012 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-22899010

10.

Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing.

Royer-Bertrand, Beryl; Torsello, Matteo; Rimoldi, Donata; El Zaoui, Ikram; Cisarova, Katarina; Pescini-Gobert, Rosanna; Raynaud, Franck; Zografos, Leonidas; Schalenbourg, Ann; Speiser, Daniel; Nicolas, Michael; Vallat, Laureen; Klein, Robert; Leyvraz, Serge; Ciriello, Giovanni; Riggi, Nicolò; Moulin, Alexandre P; Rivolta, Carlo.

Am J Hum Genet ; 99(5): 1190-1198, 2016 Nov 03.

Artigo em Inglês | MEDLINE | ID: mdl-27745836

11.

Ewing's Sarcoma. Reply.

Riggi, Nicolò; Suvà, Mario L; Stamenkovic, Ivan.

N Engl J Med ; 384(15): 1477-1478, 2021 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-33852794

12.

Ewing's Sarcoma.

Riggi, Nicolò; Suvà, Mario L; Stamenkovic, Ivan.

N Engl J Med ; 384(2): 154-164, 2021 01 14.

Artigo em Inglês | MEDLINE | ID: mdl-33497548

13.

EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells.

Riggi, Nicolò; Suvà, Mario-Luca; De Vito, Claudio; Provero, Paolo; Stehle, Jean-Christophe; Baumer, Karine; Cironi, Luisa; Janiszewska, Michalina; Petricevic, Tanja; Suvà, Domizio; Tercier, Stéphane; Joseph, Jean-Marc; Guillou, Louis; Stamenkovic, Ivan.

Genes Dev ; 24(9): 916-32, 2010 May.

Artigo em Inglês | MEDLINE | ID: mdl-20382729

14.

Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors.

Faes, Seraina; Duval, Adrian P; Planche, Anne; Uldry, Emilie; Santoro, Tania; Pythoud, Catherine; Stehle, Jean-Christophe; Horlbeck, Janine; Letovanec, Igor; Riggi, Nicolo; Demartines, Nicolas; Dormond, Olivier.

Mol Cancer ; 15(1): 78, 2016 12 05.

Artigo em Inglês | MEDLINE | ID: mdl-27919264

15.

DisP-seq reveals the genome-wide functional organization of DNA-associated disordered proteins.

Xing, Yu-Hang; Dong, Rui; Lee, Lukuo; Rengarajan, Shruthi; Riggi, Nicolò; Boulay, Gaylor; Rivera, Miguel N.

Nat Biotechnol ; 42(1): 52-64, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-37037903

16.

CIC-DUX4 Chromatin Profiling Reveals New Epigenetic Dependencies and Actionable Therapeutic Targets in CIC-Rearranged Sarcomas.

Bakaric, Arnaud; Cironi, Luisa; Praz, Viviane; Sanalkumar, Rajendran; Broye, Liliane C; Favre-Bulle, Kerria; Letovanec, Igor; Digklia, Antonia; Renella, Raffaele; Stamenkovic, Ivan; Ott, Christopher J; Nakamura, Takuro; Antonescu, Cristina R; Rivera, Miguel N; Riggi, Nicolò.

Cancers (Basel) ; 16(2)2024 Jan 21.

Artigo em Inglês | MEDLINE | ID: mdl-38275898

17.

Clear cell sarcoma: state-of-the art and perspectives.

Wetterwald, Laureline; Riggi, Nicolò; Kyriazoglou, Anastasios; Dei Tos, Giovanni; Dei Tos, Angelo; Digklia, Antonia.

Expert Rev Anticancer Ther ; 23(3): 235-242, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36811446

18.

Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity.

Sanalkumar, Rajendran; Dong, Rui; Lee, Lukuo; Xing, Yu-Hang; Iyer, Sowmya; Letovanec, Igor; La Rosa, Stefano; Finzi, Giovanna; Musolino, Elettra; Papait, Roberto; Chebib, Ivan; Nielsen, G Petur; Renella, Raffaele; Cote, Gregory M; Choy, Edwin; Aryee, Martin; Stegmaier, Kimberly; Stamenkovic, Ivan; Rivera, Miguel N; Riggi, Nicolò.

Sci Adv ; 9(13): eabo3789, 2023 03 31.

Artigo em Inglês | MEDLINE | ID: mdl-37000878

19.

Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma.

Bevill, Samantha M; Casaní-Galdón, Salvador; El Farran, Chadi A; Cytrynbaum, Eli G; Macias, Kevin A; Oldeman, Sylvie E; Oliveira, Kayla J; Moore, Molly M; Hegazi, Esmat; Adriaens, Carmen; Najm, Fadi J; Demetri, George D; Cohen, Sonia; Mullen, John T; Riggi, Nicolò; Johnstone, Sarah E; Bernstein, Bradley E.

Cell Genom ; 3(7): 100321, 2023 Jul 12.

Artigo em Inglês | MEDLINE | ID: mdl-37492096

20.

Necrotic debris and STING exert therapeutically relevant effects on tumor cholesterol homeostasis.

Katakam, Sampath; Anand, Santosh; Martin, Patricia; Riggi, Nicolo; Stamenkovic, Ivan.

Life Sci Alliance ; 5(3)2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-34983824

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