Detalhe da pesquisa
1.
The role of PIM kinases in human and mouse CD4+ T cell activation and inflammatory bowel disease.
Cell Immunol
; 272(2): 200-13, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22078270
2.
Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors.
Bioorg Med Chem Lett
; 19(13): 3637-41, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19447623
3.
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides.
Bioorg Med Chem Lett
; 19(19): 5652-6, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19709881
4.
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinediones.
Bioorg Med Chem Lett
; 19(13): 3642-6, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19457662
5.
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids.
Bioorg Med Chem Lett
; 19(19): 5648-51, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19700319
6.
Recent applications of olefin metathesis to combinatorial chemistry.
Curr Opin Chem Biol
; 8(3): 245-54, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15183322
7.
Discovery of a Novel Class of Imidazo[1,2-a]Pyridines with Potent PDGFR Activity and Oral Bioavailability.
ACS Med Chem Lett
; 5(1): 78-83, 2014 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900776
8.
Enantioselective total synthesis of the polycyclic guanidine-containing marine alkaloid (-)-batzelladine D.
Angew Chem Int Ed Engl
; 46(39): 7417-9, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17763494
9.
A potential therapeutic target for FLT3-ITD AML: PIM1 kinase.
Leuk Res
; 36(2): 224-31, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21802138
10.
Intermolecular transition metal-catalyzed [4 + 2 + 2] cycloaddition reactions: a new approach to the construction of eight-membered rings.
J Am Chem Soc
; 124(30): 8782-3, 2002 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12137516