RESUMO
A study of an outbreak of acute respiratory disease was done at the "Carlos Font Pupo" Old People's Home. Las Tunas Province, where 30 diseased old individuals were detected; grippe was diagnosed to two of them. General attack rate was 8.6%. Curative treatment with amantadine was administered to 29 old patients and chemoprophylaxis to 26, for a total of 55 old individuals treated. The evolution of the patients was satisfactory and none new case was observed. Diarrhea was the only one secondary reaction observed in a patient under chemoprophylactic treatment. The need to carry on performing similar studies is pointed out.
Assuntos
Amantadina/uso terapêutico , Surtos de Doenças/prevenção & controle , Instituição de Longa Permanência para Idosos , Influenza Humana/prevenção & controle , Doença Aguda , Idoso , Idoso de 80 Anos ou mais , Cuba , Feminino , Humanos , Influenza Humana/epidemiologia , Masculino , Infecções Respiratórias/epidemiologia , Infecções Respiratórias/prevenção & controleRESUMO
A discussion is carried out about the experiences with the application of rimantadine and amantadine to patients with influenza. The basic general results consisted in the fact that 2 of the 74 patients treated had a high cure percent (> 68.0%) within the first 72 hours after using the drug. No new diseased were found among the 40 contacts to whom chemoprophylaxis was applied. There were only 3.9% adverse reactions among the total number of people treated with amantadine.