Detalhe da pesquisa
1.
Basic science under threat: Lessons from the Skirball Institute.
Cell
; 185(5): 755-758, 2022 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35245477
2.
A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response.
Cell
; 171(7): 1625-1637.e13, 2017 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29198525
3.
ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Mol Cell
; 81(1): 88-103.e6, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33220178
4.
The IRE1ß-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells.
EMBO J
; 43(5): 719-753, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177498
5.
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response.
Proc Natl Acad Sci U S A
; 121(14): e2320013121, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38547060
6.
Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance.
Nature
; 578(7796): E24, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32051582
7.
GDF15 mediates the effects of metformin on body weight and energy balance.
Nature
; 578(7795): 444-448, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31875646
8.
An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
EMBO J
; 38(21): e102177, 2019 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31531998
9.
Diabetes, insulin and new therapeutic strategies for Parkinson's disease: Focus on glucagon-like peptide-1 receptor agonists.
Front Neuroendocrinol
; 62: 100914, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33845041
10.
Effect of antiangiogenic-based treatment and systemic inflammatory factors on outcomes in patients with BRAF v600-mutated metastatic colorectal cancer: a real-world study in Spain.
BMC Cancer
; 21(1): 64, 2021 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33446148
11.
SnapShot: The unfolded protein response.
Cell
; 140(4): 590-590.e2, 2010 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20178750
12.
Endoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in mice.
Mol Cell
; 48(1): 39-51, 2012 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22981861
13.
A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α.
J Biol Chem
; 293(20): 7766-7776, 2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29618508
14.
The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development.
J Cell Sci
; 130(18): 3040-3049, 2017 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28775151
15.
Oxidative protein folding by an endoplasmic reticulum-localized peroxiredoxin.
Mol Cell
; 40(5): 787-97, 2010 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21145486
16.
The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans.
Mol Cell
; 37(4): 529-40, 2010 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20188671
17.
Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1.
Mol Cell
; 38(2): 291-304, 2010 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20417606
18.
TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2.
BMC Biol
; 15(1): 24, 2017 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28347335
19.
PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis.
Am J Pathol
; 186(7): 1939-1951, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27181404
20.
Skeletal muscle-specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21-mediated non-cell-autonomous energy metabolism.
FASEB J
; 30(2): 798-812, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26487695