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1.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi ; 25(1): 89-92, 2008 Feb.
Artigo em Zh | MEDLINE | ID: mdl-18247314

RESUMO

OBJECTIVE: To investigate the genetic structure of X chromosome in Mongolia, Ewenki, Elunchun and Dawoer in Inner Mongolia. METHODS: Nine short tandem repeat (STR) markers on the X chromosome (DXS6789, DXS101, DXS8378, DXS7132, DXS7133, DXS7423, DXS6804, DXS6799 and HPRTB) were analyzed in the four populations from Inner Mongolian (Mongol, Ewenki,Oroqen and Daur) for their genetic diversity, forensic suitability and possible genetic affinities of the populations. Frequencies and other parameters of forensic interest were computed. RESULTS: The results revealed that the nine markers described here have a moderate degree of variability in the population groups. And there are significant differences in the genetic variability among the populations. Genetic distance and cluster analyses show very low genetic distance between Mongol and Han (Xi'an) communities. The results based on genetic distance analyses are consistent with earlier studies based on linguistic as well as immigration history and origin of these populations. CONCLUSION: The nine STR loci studied here were found not only useful in studying genetic variations between populations but also suitable for human identity testing.


Assuntos
Cromossomos Humanos X/genética , Etnicidade/genética , Variação Genética , Repetições de Microssatélites/genética , China/etnologia , Análise por Conglomerados , Feminino , Humanos , Masculino
2.
Zhong Nan Da Xue Xue Bao Yi Xue Ban ; 32(2): 276-81, 2007 Apr.
Artigo em Zh | MEDLINE | ID: mdl-17478936

RESUMO

OBJECTIVE: To determine the genetic diversity of X-TR loci, and to evaluate the genetic structure X chromosome's of Ewenki nationality and its affinity with other nationalities. METHODS: We chose 9 X-TR (DXS6804, DXS7133, DXS101, DXS6789, DXS6799, DXS7423, HPRTB, DXS8378, DXS7132) as genetic markers from 99 irrelative individules to determine the genetic diversity of Ewenki in Inner Mongolian. Cluster analysis and phylogenic trees was applied to show the genetic distance among the nationalities. RESULTS: We got 51 alleles in the studied population, with the frequency diverse between 0.0109 and 0.6863. Genotype frequency was from 0.0217 to 0.3778. Heterozygosity(H),the power of discrimination(PD) and the polymorphism information conten (PIC) were consistent with the forensic application. Cluster analysis and phylogenic trees revealed that Ewenki nationality had estrangement genetic affinity with the other 3 major nationalities in inner mongolia and Han nationality in Xi'an. CONCLUSION: The genetic information demonstrates that the 9 chosen gene makers were highly informative loci and are suitable for population genetics research and forensic application.


Assuntos
Cromossomos Humanos X/genética , Marcadores Genéticos/genética , Repetições de Microssatélites/genética , Polimorfismo Genético , China , Análise por Conglomerados , Etnicidade/classificação , Etnicidade/genética , Feminino , Frequência do Gene , Variação Genética , Genótipo , Humanos , Masculino , Filogenia
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