Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Architecture of the outbred brown fat proteome defines regulators of metabolic physiology.

Xiao, Haopeng; Bozi, Luiz H M; Sun, Yizhi; Riley, Christopher L; Philip, Vivek M; Chen, Mandy; Li, Jiaming; Zhang, Tian; Mills, Evanna L; Emont, Margo P; Sun, Wenfei; Reddy, Anita; Garrity, Ryan; Long, Jiani; Becher, Tobias; Vitas, Laura Potano; Laznik-Bogoslavski, Dina; Ordonez, Martha; Liu, Xinyue; Chen, Xiong; Wang, Yun; Liu, Weihai; Tran, Nhien; Liu, Yitong; Zhang, Yang; Cypess, Aaron M; White, Andrew P; He, Yuchen; Deng, Rebecca; Schöder, Heiko; Paulo, Joao A; Jedrychowski, Mark P; Banks, Alexander S; Tseng, Yu-Hua; Cohen, Paul; Tsai, Linus T; Rosen, Evan D; Klein, Samuel; Chondronikola, Maria; McAllister, Fiona E; Van Bruggen, Nick; Huttlin, Edward L; Spiegelman, Bruce M; Churchill, Gary A; Gygi, Steven P; Chouchani, Edward T.

Cell ; 185(24): 4654-4673.e28, 2022 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-36334589

2.

Control of lipolysis by a population of oxytocinergic sympathetic neurons.

Li, Erwei; Wang, Luhong; Wang, Daqing; Chi, Jingyi; Lin, Zeran; Smith, Gordon I; Klein, Samuel; Cohen, Paul; Rosen, Evan D.

Nature ; 625(7993): 175-180, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38093006

3.

What we talk about when we talk about fat.

Rosen, Evan D; Spiegelman, Bruce M.

Cell ; 156(1-2): 20-44, 2014 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-24439368

4.

IRF4 is a key thermogenic transcriptional partner of PGC-1α.

Kong, Xingxing; Banks, Alexander; Liu, Tiemin; Kazak, Lawrence; Rao, Rajesh R; Cohen, Paul; Wang, Xun; Yu, Songtao; Lo, James C; Tseng, Yu-Hua; Cypess, Aaron M; Xue, Ruidan; Kleiner, Sandra; Kang, Sona; Spiegelman, Bruce M; Rosen, Evan D.

Cell ; 158(1): 69-83, 2014 Jul 03.

Artigo em Inglês | MEDLINE | ID: mdl-24995979

5.

A single-cell atlas of human and mouse white adipose tissue.

Emont, Margo P; Jacobs, Christopher; Essene, Adam L; Pant, Deepti; Tenen, Danielle; Colleluori, Georgia; Di Vincenzo, Angelica; Jørgensen, Anja M; Dashti, Hesam; Stefek, Adam; McGonagle, Elizabeth; Strobel, Sophie; Laber, Samantha; Agrawal, Saaket; Westcott, Gregory P; Kar, Amrita; Veregge, Molly L; Gulko, Anton; Srinivasan, Harini; Kramer, Zachary; De Filippis, Eleanna; Merkel, Erin; Ducie, Jennifer; Boyd, Christopher G; Gourash, William; Courcoulas, Anita; Lin, Samuel J; Lee, Bernard T; Morris, Donald; Tobias, Adam; Khera, Amit V; Claussnitzer, Melina; Pers, Tune H; Giordano, Antonio; Ashenberg, Orr; Regev, Aviv; Tsai, Linus T; Rosen, Evan D.

Nature ; 603(7903): 926-933, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35296864

6.

Comparative epigenomic analysis of murine and human adipogenesis.

Mikkelsen, Tarjei S; Xu, Zhao; Zhang, Xiaolan; Wang, Li; Gimble, Jeffrey M; Lander, Eric S; Rosen, Evan D.

Cell ; 143(1): 156-69, 2010 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-20887899

7.

Palmitate Potentiates Lipopolysaccharide-Induced IL-6 Production via Coordinated Acetylation of H3K9/H3K18, p300, and RNA Polymerase II.

Kochumon, Shihab; Jacob, Texy; Koshy, Merin; Al-Rashed, Fatema; Sindhu, Sardar; Al-Ozairi, Ebaa; Al-Mulla, Fahd; Rosen, Evan D; Ahmad, Rasheed.

J Immunol ; 209(4): 731-741, 2022 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-35896337

8.

Author Correction: A single-cell atlas of human and mouse white adipose tissue.

Emont, Margo P; Jacobs, Christopher; Essene, Adam L; Pant, Deepti; Tenen, Danielle; Colleluori, Georgia; Di Vincenzo, Angelica; Jørgensen, Anja M; Dashti, Hesam; Stefek, Adam; McGonagle, Elizabeth; Strobel, Sophie; Laber, Samantha; Agrawal, Saaket; Westcott, Gregory P; Kar, Amrita; Veregge, Molly L; Gulko, Anton; Srinivasan, Harini; Kramer, Zachary; De Filippis, Eleanna; Merkel, Erin; Ducie, Jennifer; Boyd, Christopher G; Gourash, William; Courcoulas, Anita; Lin, Samuel J; Lee, Bernard T; Morris, Donald; Tobias, Adam; Khera, Amit V; Claussnitzer, Melina; Pers, Tune H; Giordano, Antonio; Ashenberg, Orr; Regev, Aviv; Tsai, Linus T; Rosen, Evan D.

Nature ; 620(7973): E14, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37495702

9.

Anti-Insulin Receptor Antibody for Malignant Insulinoma and Refractory Hypoglycemia.

Osataphan, Soravis; Vamvini, Maria; Rosen, Evan D; Pei, Lei; Erlikh, Natanie; Singh, Gurcharan; Dhorajiya, Poojaben; Parker, J Anthony; Dreyfuss, Jonathan M; Rattani, Ahmed; Patti, Mary-Elizabeth.

N Engl J Med ; 389(8): 767-769, 2023 Aug 24.

Artigo em Inglês | MEDLINE | ID: mdl-37611129

10.

The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation.

Ahmad, Rasheed; Al-Roub, Areej; Kochumon, Shihab; Akther, Nadeem; Thomas, Reeby; Kumari, Manju; Koshy, Merin S; Tiss, Ali; Hannun, Yusuf A; Tuomilehto, Jaakko; Sindhu, Sardar; Rosen, Evan D.

J Immunol ; 200(10): 3599-3611, 2018 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-29632147

11.

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction.

Kazak, Lawrence; Chouchani, Edward T; Stavrovskaya, Irina G; Lu, Gina Z; Jedrychowski, Mark P; Egan, Daniel F; Kumari, Manju; Kong, Xingxing; Erickson, Brian K; Szpyt, John; Rosen, Evan D; Murphy, Michael P; Kristal, Bruce S; Gygi, Steven P; Spiegelman, Bruce M.

Proc Natl Acad Sci U S A ; 114(30): 7981-7986, 2017 07 25.

Artigo em Inglês | MEDLINE | ID: mdl-28630339

12.

Charting a dynamic DNA methylation landscape of the human genome.

Ziller, Michael J; Gu, Hongcang; Müller, Fabian; Donaghey, Julie; Tsai, Linus T-Y; Kohlbacher, Oliver; De Jager, Philip L; Rosen, Evan D; Bennett, David A; Bernstein, Bradley E; Gnirke, Andreas; Meissner, Alexander.

Nature ; 500(7463): 477-81, 2013 Aug 22.

Artigo em Inglês | MEDLINE | ID: mdl-23925113

13.

Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes.

Majithia, Amit R; Flannick, Jason; Shahinian, Peter; Guo, Michael; Bray, Mark-Anthony; Fontanillas, Pierre; Gabriel, Stacey B; Rosen, Evan D; Altshuler, David.

Proc Natl Acad Sci U S A ; 111(36): 13127-32, 2014 Sep 09.

Artigo em Inglês | MEDLINE | ID: mdl-25157153

14.

Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism.

Bozec, Aline; Bakiri, Latifa; Jimenez, Maria; Rosen, Evan D; Catalá-Lehnen, Philip; Schinke, Thorsten; Schett, Georg; Amling, Michael; Wagner, Erwin F.

J Cell Sci ; 126(Pt 23): 5432-40, 2013 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-24046454

15.

Regulation of early adipose commitment by Zfp521.

Kang, Sona; Akerblad, Peter; Kiviranta, Riku; Gupta, Rana K; Kajimura, Shingo; Griffin, Michael J; Min, Jie; Baron, Roland; Rosen, Evan D.

PLoS Biol ; 10(11): e1001433, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-23209378

16.

Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes.

Griffin, Michael J; Zhou, Yiming; Kang, Sona; Zhang, Xiaolan; Mikkelsen, Tarjei S; Rosen, Evan D.

J Biol Chem ; 288(50): 35925-39, 2013 Dec 13.

Artigo em Inglês | MEDLINE | ID: mdl-24174531

17.

Burning Fat by Bugging the System.

Rosen, Evan D.

N Engl J Med ; 374(9): 885-7, 2016 Mar 03.

Artigo em Inglês | MEDLINE | ID: mdl-26962910

18.

Uncoupling protein 1-driven Cre (Ucp1-Cre) is expressed in the epithelial cells of mammary glands and various non-adipose tissues.

Kim, Kyungchan; Wann, Jamie; Kim, Hyeong-Geug; So, Jisun; Rosen, Evan D; Roh, Hyun Cheol.

Mol Metab ; 84: 101948, 2024 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-38677508

19.

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming.

Holman, Corey D; Sakers, Alexander P; Calhoun, Ryan P; Cheng, Lan; Fein, Ethan C; Jacobs, Christopher; Tsai, Linus; Rosen, Evan D; Seale, Patrick.

bioRxiv ; 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-36993336

20.

Protocol for flow cytometry-assisted single-nucleus RNA sequencing of human and mouse adipose tissue with sample multiplexing.

Gulko, Anton; Essene, Adam; Belmont-Rausch, Dylan Matthew; Veregge, Molly; Pant, Deepti; Tenen, Danielle; Kapel, Benedicte Schultz; Emont, Margo P; Pers, Tune H; Rosen, Evan D; Tsai, Linus T.

STAR Protoc ; 5(1): 102893, 2024 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-38416649

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