Detalhe da pesquisa
1.
CRISPR/dCas9 DNA methylation editing is heritable during human hematopoiesis and shapes immune progeny.
Proc Natl Acad Sci U S A
; 120(34): e2300224120, 2023 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37579157
2.
A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation.
RNA
; 28(9): 1224-1238, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35768279
3.
Germline ERCC excision repair 6 like 2 (ERCC6L2) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment.
Br J Haematol
; 199(5): 754-764, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36156210
4.
Adaptive from Innate: Human IFN-γ+CD4+ T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults.
J Immunol
; 199(5): 1696-1705, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28754679
5.
Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes.
Signal Transduct Target Ther
; 8(1): 80, 2023 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36843114
6.
The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts.
Res Sq
; 2023 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37090662
7.
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia.
Sci Transl Med
; 15(685): eabn5135, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36857430
8.
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
Nat Commun
; 14(1): 2132, 2023 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059720
9.
Myelodysplastic syndrome can propagate from the multipotent progenitor compartment.
Haematologica
; 102(1): e7-e10, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27758823
10.
Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment.
Sci Signal
; 15(730): eabl7989, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35439021
11.
The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes.
Nat Commun
; 13(1): 7619, 2022 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36494342
12.
ER Stress and Unfolded Protein Response in Leukemia: Friend, Foe, or Both?
Biomolecules
; 11(2)2021 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33573353
13.
Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells.
Blood Cancer Discov
; 2(2): 135-145, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33778768
14.
Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis.
J Exp Med
; 218(3)2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33507234
15.
Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers.
Cells
; 9(3)2020 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32111004
16.
Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia.
J Clin Invest
; 130(6): 3038-3050, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32364536
17.
Correction: Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment.
Leukemia
; 34(7): 1973, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005921
18.
Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment.
Leukemia
; 34(6): 1658-1668, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31776464
19.
Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches.
J Exp Med
; 215(3): 729-743, 2018 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29453226
20.
c-Fos induces chondrogenic tumor formation in immortalized human mesenchymal progenitor cells.
Sci Rep
; 8(1): 15615, 2018 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30353072