Detalhe da pesquisa
1.
Chromenone derivatives as novel pharmacological chaperones for retinitis pigmentosa-linked rod opsin mutants.
Hum Mol Genet
; 31(20): 3439-3457, 2022 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35642742
2.
Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal.
J Biol Chem
; 298(8): 102266, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35850308
3.
Systematic profiling of temperature- and retinal-sensitive rhodopsin variants by deep mutational scanning.
J Biol Chem
; 297(6): 101359, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34756884
4.
Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis.
J Am Chem Soc
; 141(1): 204-215, 2019 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30537820
5.
The Retinitis Pigmentosa-Linked Mutations in Transmembrane Helix 5 of Rhodopsin Disrupt Cellular Trafficking Regardless of Oligomerization State.
Biochemistry
; 57(35): 5188-5201, 2018 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30085663
6.
The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling.
J Cell Biol
; 222(6)2023 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37071417
7.
General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variants.
Cell Chem Biol
; 30(6): 632-642.e5, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37253358
8.
Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning.
Sci Adv
; 6(10): eaay7505, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32181350