Detalhe da pesquisa
1.
Abuse and misuse of second-generation antipsychotics: An analysis using VigiBase, the World Health Organisation pharmacovigilance database.
Br J Clin Pharmacol
; 88(10): 4646-4653, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35633029
2.
Opioid misuse in community pharmacy patients with chronic non-cancer pain.
Br J Clin Pharmacol
; 88(5): 2306-2314, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34859478
3.
Soluble guanylate cyclase stimulators for the treatment of hypertension: Discovery of MK-2947.
Bioorg Med Chem Lett
; 30(21): 127574, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32980512
4.
Conformational dynamics and role of the acidic pocket in ASIC pH-dependent gating.
Proc Natl Acad Sci U S A
; 114(14): 3768-3773, 2017 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320963
5.
Impact of recommended changes in labor management for prevention of the primary cesarean delivery.
Am J Obstet Gynecol
; 218(3): 341.e1-341.e9, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29291413
6.
Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophores.
Bioorg Med Chem Lett
; 27(11): 2559-2566, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28431879
7.
The Renal Outer Medullary Potassium Channel Inhibitor, MK-7145, Lowers Blood Pressure, and Manifests Features of Bartter's Syndrome Type II Phenotype.
J Pharmacol Exp Ther
; 359(1): 194-206, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27432892
8.
Differentiation of ROMK potency from hERG potency in the phenacetyl piperazine series through heterocycle incorporation.
Bioorg Med Chem Lett
; 26(9): 2339-43, 2016 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27017115
9.
Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffold.
Bioorg Med Chem Lett
; 26(23): 5695-5702, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27839686
10.
Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats.
Cardiovasc Diabetol
; 14: 29, 2015 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25888997
11.
Serious Complications Associated With the Injection of Ethylphenidate: 2 Case Reports.
J Clin Psychopharmacol
; 40(1): 87-89, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31860611
12.
Pharmacologic inhibition of the renal outer medullary potassium channel causes diuresis and natriuresis in the absence of kaliuresis.
J Pharmacol Exp Ther
; 348(1): 153-64, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24142912
13.
Molecular determinants of desensitization in an ENaC/degenerin channel.
FASEB J
; 27(12): 5034-45, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24018065
14.
Challenges in listeriosis cluster and outbreak investigations, Province of Quebec, 1997-2011.
Foodborne Pathog Dis
; 11(1): 1-7, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24134667
15.
Sequential immunotherapy: towards cures for autoimmunity.
Nat Rev Drug Discov
; 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38839912
16.
Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one.
Bioorg Med Chem Lett
; 23(21): 5829-32, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24075732
17.
Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain L-2-hydroxy acid oxidase.
Bioorg Med Chem Lett
; 22(13): 4341-7, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22658862
18.
Ten-year trends in hospitalizations related to cocaine abuse in France.
Fundam Clin Pharmacol
; 36(6): 1128-1132, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35801616
19.
Management of Pregabalin Use Disorder: A Case Series.
J Psychoactive Drugs
; 54(4): 386-391, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34930090
20.
Calcium regulates acid-sensing ion channel 3 activation by competing with protons in the channel pore and at an allosteric binding site.
Open Biol
; 12(12): 220243, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36541099