Detalhe da pesquisa
1.
Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis.
N Engl J Med
; 385(24): 2219-2229, 2021 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34879448
2.
Tapinarof Cream 1% Once Daily: Significant Efficacy in the Treatment of Moderate to Severe Atopic Dermatitis in Adults and Children Down to 2 Years of Age in the Pivotal Phase 3 ADORING Trials.
J Am Acad Dermatol
; 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38777187
3.
Targeting the Aryl Hydrocarbon Receptor to Address the Challenges of Atopic Dermatitis.
J Drugs Dermatol
; 23(2): 23-28, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38306128
4.
Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A clinical review.
J Allergy Clin Immunol
; 2023 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38154665
5.
One-year safety and efficacy of tapinarof cream for the treatment of plaque psoriasis: Results from the PSOARING 3 trial.
J Am Acad Dermatol
; 87(4): 800-806, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35772599
6.
A phase 2b, randomized clinical trial of tapinarof cream for the treatment of plaque psoriasis: Secondary efficacy and patient-reported outcomes.
J Am Acad Dermatol
; 84(3): 624-631, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32446832
7.
Efficacy and patient-reported outcomes from a phase 2b, randomized clinical trial of tapinarof cream for the treatment of adolescents and adults with atopic dermatitis.
J Am Acad Dermatol
; 84(3): 632-638, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32502588
8.
Tapinarof in the treatment of psoriasis: A review of the unique mechanism of action of a novel therapeutic aryl hydrocarbon receptor-modulating agent.
J Am Acad Dermatol
; 84(4): 1059-1067, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33157177
9.
Tapinarof cream 1% once daily and benvitimod 1% twice daily are 2 distinct topical medications.
J Am Acad Dermatol
; 85(3): e201-e202, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34111499
10.
Tapinarof-associated folliculitis is generally mild, self-limiting, and rarely interferes with therapy.
J Am Acad Dermatol
; 85(1): e39-e40, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33676999
11.
The preponderance of evidence supports an aryl hydrocarbon receptor-dependent mechanism of action of tapinarof.
J Am Acad Dermatol
; 85(1): e35-e36, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33677005
12.
Targeting O-glycosyltransferase (OGT) to promote healing of diabetic skin wounds.
J Biol Chem
; 289(9): 5462-6, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24398691
13.
A pathophysiologic role for epidermal growth factor receptor in pemphigus acantholysis.
J Biol Chem
; 288(13): 9447-56, 2013 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23404504
14.
Rapid Improvements in Itch with Tapinarof Cream 1% Once Daily in Two Phase 3 Trials in Adults with Mild to Severe Plaque Psoriasis.
Dermatol Ther (Heidelb)
; 14(1): 201-211, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38123875
15.
Tapinarof Cream 1% Once Daily for the Treatment of Plaque Psoriasis: Case Photography of Clinical Outcomes from Three Phase 3 Trials.
Dermatol Ther (Heidelb)
; 13(10): 2443-2460, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37697121
16.
The C5a receptor on mast cells is critical for the autoimmune skin-blistering disease bullous pemphigoid.
J Biol Chem
; 286(17): 15003-9, 2011 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21393236
17.
Protective endogenous cyclic adenosine 5'-monophosphate signaling triggered by pemphigus autoantibodies.
J Immunol
; 185(11): 6831-8, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21037102
18.
Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis.
J Biol Chem
; 285(49): 38684-91, 2010 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-20926386
19.
p38MAPK signaling and desmoglein-3 internalization are linked events in pemphigus acantholysis.
J Biol Chem
; 285(12): 8936-41, 2010 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20093368
20.
Autoantibodies in the autoimmune disease pemphigus foliaceus induce blistering via p38 mitogen-activated protein kinase-dependent signaling in the skin.
Am J Pathol
; 173(6): 1628-36, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18988808