Detalhe da pesquisa
1.
Insulin receptor plays a central role in skin carcinogenesis by regulating cytoskeleton assembly.
FASEB J
; 33(2): 2241-2251, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30332298
2.
Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD.
Hum Mol Genet
; 25(8): 1600-18, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908611
3.
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Genome Res
; 25(5): 701-13, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25908449
4.
Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.
Proc Natl Acad Sci U S A
; 111(33): 12085-90, 2014 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092318
5.
Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier.
Acta Neuropathol
; 129(1): 39-52, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25388784
6.
Development and application of a DNA microarray-based yeast two-hybrid system.
Nucleic Acids Res
; 41(3): 1496-507, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23275563
7.
Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
PLoS Genet
; 8(8): e1002897, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22916034
8.
C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD.
Acta Neuropathol
; 128(4): 525-41, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24806409
9.
EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.
Proc Natl Acad Sci U S A
; 107(17): 7710-5, 2010 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385841
10.
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.
Nat Commun
; 13(1): 6830, 2022 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36369285
11.
UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome.
Nucleic Acids Res
; 37(Database issue): D657-60, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18984619
12.
mTOR-dependent translation amplifies microglia priming in aging mice.
J Clin Invest
; 131(1)2021 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33108356
13.
Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.
Nat Cell Biol
; 23(12): 1224-1239, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34876685
14.
Comparison and consolidation of microarray data sets of human tissue expression.
BMC Genomics
; 11: 305, 2010 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20465848
15.
Neuronal Transcriptome from C9orf72 Repeat Expanded Human Tissue is Associated with Loss of C9orf72 Function.
Free Neuropathol
; 12020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32905541
16.
RNA Sequencing of Human Peripheral Blood Cells Indicates Upregulation of Immune-Related Genes in Huntington's Disease.
Front Neurol
; 11: 573560, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33329316
17.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Cell Rep
; 32(7): 108050, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814053
18.
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons.
Cell Rep
; 27(5): 1409-1421.e6, 2019 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31042469
19.
Author Correction: Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.
Nat Cell Biol
; 24(1): 123, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34983954
20.
mTOR-dependent translation amplifies microglia priming in aging mice.
J Clin Invest
; 131(20)2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34651589