Detalhe da pesquisa
1.
An essential role for the Zn2+ transporter ZIP7 in B cell development.
Nat Immunol
; 20(3): 350-361, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718914
2.
Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic ß-cell survival and function.
FASEB J
; 38(8): e23610, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38661000
3.
Destabilization of ß Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes.
Proc Natl Acad Sci U S A
; 119(11): e2113074119, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35254894
4.
An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study.
Diabetologia
; 67(5): 885-894, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38374450
5.
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.
Diabetologia
; 67(6): 1079-1094, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38512414
6.
Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing.
Biochem J
; 480(11): 773-789, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37284792
7.
Islet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell.
Diabetologia
; 66(11): 1971-1982, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37488322
8.
New-onset type 1 diabetes and severe acute respiratory syndrome coronavirus 2 infection.
Immunol Cell Biol
; 101(3): 191-203, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36529987
9.
Control of human pancreatic beta cell kinome by glucagon-like peptide-1 receptor biased agonism.
Diabetes Obes Metab
; 25(8): 2105-2119, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37039251
10.
Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.
Diabetologia
; 65(6): 997-1011, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35294578
11.
Genetic and biased agonist-mediated reductions in ß-arrestin recruitment prolong cAMP signaling at glucagon family receptors.
J Biol Chem
; 296: 100133, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268378
12.
Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.
PLoS Biol
; 17(8): e3000097, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31430273
13.
In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonist.
Diabetes Obes Metab
; 24(11): 2090-2101, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35676825
14.
Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice.
Diabetologia
; 64(1): 129-141, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33068125
15.
Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.
Diabetologia
; 64(4): 850-864, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33492421
16.
Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study.
Diabetologia
; 64(9): 1982-1989, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34110439
17.
Age matters: Grading granule secretion in beta cells.
J Biol Chem
; 295(27): 8912-8913, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32620690
18.
A polysaccharide extract from the medicinal plant Maidong inhibits the IKK-NF-κB pathway and IL-1ß-induced islet inflammation and increases insulin secretion.
J Biol Chem
; 295(36): 12573-12587, 2020 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32605924
19.
The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.
Nature
; 524(7565): 356-60, 2015 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26258299
20.
Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity.
Proc Natl Acad Sci U S A
; 115(32): E7642-E7649, 2018 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30038024