Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity.

Barreira da Silva, Rosa; Leitao, Ricardo M; Pechuan-Jorge, Ximo; Werneke, Scott; Oeh, Jason; Javinal, Vincent; Wang, Yingyun; Phung, Wilson; Everett, Christine; Nonomiya, Jim; Arnott, David; Lu, Cheng; Hsiao, Yi-Chun; Koerber, James T; Hötzel, Isidro; Ziai, James; Modrusan, Zora; Pillow, Thomas H; Roose-Girma, Merone; Schartner, Jill M; Merchant, Mark; Rutz, Sascha; Eidenschenk, Céline; Mellman, Ira; Albert, Matthew L.

Nat Immunol ; 23(4): 568-580, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35314846

2.

Regulation and functions of the IL-10 family of cytokines in inflammation and disease.

Ouyang, Wenjun; Rutz, Sascha; Crellin, Natasha K; Valdez, Patricia A; Hymowitz, Sarah G.

Annu Rev Immunol ; 29: 71-109, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21166540

3.

c-Maf-dependent T_reg cell control of intestinal T_H17 cells and IgA establishes host-microbiota homeostasis.

Neumann, Christian; Blume, Jonas; Roy, Urmi; Teh, Peggy P; Vasanthakumar, Ajithkumar; Beller, Alexander; Liao, Yang; Heinrich, Frederik; Arenzana, Teresita L; Hackney, Jason A; Eidenschenk, Celine; Gálvez, Eric J C; Stehle, Christina; Heinz, Gitta A; Maschmeyer, Patrick; Sidwell, Tom; Hu, Yifang; Amsen, Derk; Romagnani, Chiara; Chang, Hyun-Dong; Kruglov, Andrey; Mashreghi, Mir-Farzin; Shi, Wei; Strowig, Till; Rutz, Sascha; Kallies, Axel; Scheffold, Alexander.

Nat Immunol ; 20(4): 471-481, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30778241

4.

Author Correction: c-Maf-dependent T_reg cell control of intestinal T_H17 cells and IgA establishes host-microbiota homeostasis.

Neumann, Christian; Blume, Jonas; Roy, Urmi; Teh, Peggy P; Vasanthakumar, Ajithkumar; Beller, Alexander; Liao, Yang; Heinrich, Frederik; Arenzana, Teresita L; Hackney, Jason A; Eidenschenk, Celine; Gálvez, Eric J C; Stehle, Christina; Heinz, Gitta A; Maschmeyer, Patrick; Sidwell, Tom; Hu, Yifang; Amsen, Derk; Romagnani, Chiara; Chang, Hyun-Dong; Kruglov, Andrey; Mashreghi, Mir-Farzin; Shi, Wei; Strowig, Till; Rutz, Sascha; Kallies, Axel; Scheffold, Alexander.

Nat Immunol ; 2024 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-38783161

5.

Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection.

Muñoz, Melba; Eidenschenk, Celine; Ota, Naruhisa; Wong, Kit; Lohmann, Uwe; Kühl, Anja A; Wang, Xiaoting; Manzanillo, Paolo; Li, Yun; Rutz, Sascha; Zheng, Yan; Diehl, Lauri; Kayagaki, Nobuhiko; van Lookeren-Campagne, Menno; Liesenfeld, Oliver; Heimesaat, Markus; Ouyang, Wenjun.

Immunity ; 42(2): 321-331, 2015 Feb 17.

Artigo em Inglês | MEDLINE | ID: mdl-25680273

6.

The Itch to degrade ROR-Î³t.

Rutz, Sascha; Ouyang, Wenjun.

Nat Immunol ; 17(8): 898-900, 2016 07 19.

Artigo em Inglês | MEDLINE | ID: mdl-27434002

7.

Transcription factor c-Maf mediates the TGF-ß-dependent suppression of IL-22 production in T(H)17 cells.

Rutz, Sascha; Noubade, Rajkumar; Eidenschenk, Céline; Ota, Naruhisa; Zeng, Wenwen; Zheng, Yan; Hackney, Jason; Ding, Jiabing; Singh, Harinder; Ouyang, Wenjun.

Nat Immunol ; 12(12): 1238-45, 2011 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-22001828

8.

Functions and regulation of T cell-derived interleukin-10.

Neumann, Christian; Scheffold, Alexander; Rutz, Sascha.

Semin Immunol ; 44: 101344, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-31727465

9.

Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.

Rutz, Sascha; Kayagaki, Nobuhiko; Phung, Qui T; Eidenschenk, Celine; Noubade, Rajkumar; Wang, Xiaoting; Lesch, Justin; Lu, Rongze; Newton, Kim; Huang, Oscar W; Cochran, Andrea G; Vasser, Mark; Fauber, Benjamin P; DeVoss, Jason; Webster, Joshua; Diehl, Lauri; Modrusan, Zora; Kirkpatrick, Donald S; Lill, Jennie R; Ouyang, Wenjun; Dixit, Vishva M.

Nature ; 518(7539): 417-21, 2015 Feb 19.

Artigo em Inglês | MEDLINE | ID: mdl-25470037

10.

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.

Noubade, Rajkumar; Wong, Kit; Ota, Naruhisa; Rutz, Sascha; Eidenschenk, Celine; Valdez, Patricia A; Ding, Jiabing; Peng, Ivan; Sebrell, Andrew; Caplazi, Patrick; DeVoss, Jason; Soriano, Robert H; Sai, Tao; Lu, Rongze; Modrusan, Zora; Hackney, Jason; Ouyang, Wenjun.

Nature ; 509(7499): 235-9, 2014 May 08.

Artigo em Inglês | MEDLINE | ID: mdl-24739962

11.

IL-22, not simply a Th17 cytokine.

Rutz, Sascha; Eidenschenk, Céline; Ouyang, Wenjun.

Immunol Rev ; 252(1): 116-32, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23405899

12.

Regulation of Interleukin-10 Expression.

Rutz, Sascha; Ouyang, Wenjun.

Adv Exp Med Biol ; 941: 89-116, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-27734410

13.

Role of IL-22 in microbial host defense.

Eidenschenk, Celine; Rutz, Sascha; Liesenfeld, Oliver; Ouyang, Wenjun.

Curr Top Microbiol Immunol ; 380: 213-36, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25004820

14.

Regulation of epithelial immunity by IL-17 family cytokines.

Pappu, Rajita; Rutz, Sascha; Ouyang, Wenjun.

Trends Immunol ; 33(7): 343-9, 2012 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-22476048

15.

Preclinical and translational pharmacology of afucosylated anti-CCR8 antibody for depletion of tumour-infiltrating regulatory T cells.

Gampa, Gautham; Spinosa, Phillip; Getz, Jennifer; Zhong, Yu; Halpern, Wendy; Esen, Emel; Davies, John; Chou, Cassie; Kwong, Mandy; Wang, Yingyun; Arenzana, Teresita L; Shivva, Vittal; Huseni, Mahrukh; Hsieh, Robert; Schartner, Jill; Koerber, James T; Rutz, Sascha; Hosseini, Iraj.

Br J Pharmacol ; 181(13): 2033-2052, 2024 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-38486310

16.

Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity.

Guidi, Riccardo; Wedeles, Christopher; Xu, Daqi; Kolmus, Krzysztof; Headland, Sarah E; Teng, Grace; Guillory, Joseph; Zeng, Yi Jimmy; Cheung, Tommy K; Chaudhuri, Subhra; Modrusan, Zora; Liang, Yuxin; Horswell, Stuart; Haley, Benjamin; Rutz, Sascha; Rose, Christopher; Franke, Yvonne; Kirkpatrick, Donald S; Hackney, Jason A; Wilson, Mark S.

Cell Rep ; 42(12): 113515, 2023 12 26.

Artigo em Inglês | MEDLINE | ID: mdl-38096048

17.

Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.

Sun, Dawei; Sun, Yonglian; Janezic, Eric; Zhou, Tricia; Johnson, Matthew; Azumaya, Caleigh; Noreng, Sigrid; Chiu, Cecilia; Seki, Akiko; Arenzana, Teresita L; Nicoludis, John M; Shi, Yongchang; Wang, Baomei; Ho, Hoangdung; Joshi, Prajakta; Tam, Christine; Payandeh, Jian; Comps-Agrar, Laëtitia; Wang, Jianyong; Rutz, Sascha; Koerber, James T; Masureel, Matthieu.

Nat Commun ; 14(1): 7940, 2023 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-38040762

18.

Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis.

Calderón-Gómez, Elisabeth; Lampropoulou, Vicky; Shen, Ping; Neves, Patricia; Roch, Toralf; Stervbo, Ulrik; Rutz, Sascha; Kühl, Anja A; Heppner, Frank L; Loddenkemper, Christoph; Anderton, Stephen M; Kanellopoulos, Jean M; Charneau, Pierre; Fillatreau, Simon.

Eur J Immunol ; 41(6): 1696-708, 2011 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-21469107

19.

Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis.

Kassner, Nadine; Krueger, Manuela; Yagita, Hideo; Dzionek, Andrzej; Hutloff, Andreas; Kroczek, Richard; Scheffold, Alexander; Rutz, Sascha.

J Immunol ; 184(2): 550-4, 2010 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-20008296

20.

Plasmid-Based Donor Templates for Nonviral CRISPR/Cas9-Mediated Gene Knock-In in Human T Cells.

Senger, Kate; Akhmetzyanova, Ilseyar; Haley, Benjamin; Rutz, Sascha; Oh, Soyoung A.

Curr Protoc ; 2(9): e538, 2022 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-36130036

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