Detalhe da pesquisa
1.
Structure-Based De Novo Design for the Discovery of Miniprotein Inhibitors Targeting Oncogenic Mutant BRAF.
Int J Mol Sci
; 25(10)2024 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38791574
2.
Phospholipid transfer function of PTPIP51 at mitochondria-associated ER membranes.
EMBO Rep
; 22(6): e51323, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33938112
3.
Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research.
Molecules
; 26(6)2021 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33802888
4.
Crystal structure of the mouse endonuclease G.
Biochem Biophys Res Commun
; 526(1): 35-40, 2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32192768
5.
Crystal Structure of the Kinase Domain of MerTK in Complex with AZD7762 Provides Clues for Structure-Based Drug Development.
Int J Mol Sci
; 21(21)2020 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33114206
6.
Two intermediate states of the conformational switch in dual specificity phosphatase 13a.
Pharmacol Res
; 128: 211-219, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29106959
7.
BetaSCPWeb: side-chain prediction for protein structures using Voronoi diagrams and geometry prioritization.
Nucleic Acids Res
; 44(W1): W416-23, 2016 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27151195
8.
BetaCavityWeb: a webserver for molecular voids and channels.
Nucleic Acids Res
; 43(W1): W413-8, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25904629
9.
Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extension.
Bioorg Med Chem Lett
; 26(1): 87-93, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26602279
10.
Structure of the catalytic phosphatase domain of MTMR8: implications for dimerization, membrane association and reversible oxidation.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 7): 1528-39, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26143924
11.
BetaVoid: molecular voids via beta-complexes and Voronoi diagrams.
Proteins
; 82(9): 1829-49, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24677176
12.
The family-wide structure and function of human dual-specificity protein phosphatases.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 2): 421-35, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24531476
13.
Protein purification, crystallization, and structure determination of transcription factor YhaJ in complex with DNT metabolites.
STAR Protoc
; 5(2): 102999, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38573865
14.
Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 8): 1522-9, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23897475
15.
Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn.
EMBO J
; 28(22): 3564-78, 2009 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19816407
16.
Structural basis of transcription factor YhaJ for DNT detection.
iScience
; 26(10): 107984, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37822509
17.
Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening.
Bioorg Med Chem Lett
; 22(20): 6333-7, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22989533
18.
Structure-based virtual screening approach to the discovery of novel PTPMT1 phosphatase inhibitors.
Bioorg Med Chem Lett
; 22(2): 1271-5, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22115589
19.
Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity.
Bioorg Med Chem Lett
; 22(1): 323-6, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22137788
20.
Crystal structure of the catalytic domain of human RPTPH.
Acta Crystallogr F Struct Biol Commun
; 78(Pt 7): 265-269, 2022 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35787553