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J Nerv Ment Dis ; 199(1): 30-7, 2011 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21206244

RESUMO

The aim of the current study was to investigate the levels of social and physical anhedonia, as measured with the Chapman Scales for social and physical anhedonia in groups of patients with schizophrenia spectrum psychosis (n = 91), their unaffected siblings (n = 105), and control subjects drawn from a general population (n = 67). The second aim was to explore the effect of physical and social anhedonia on neuropsychological variables. Subjects with schizophrenia spectrum disorder had significantly more anhedonia than population controls, but the unaffected siblings did not differ from controls. Subjects with schizophrenia spectrum disorders had generalized cognitive deficits. Unaffected sibling status predicted impairments in executive and performance speed measures. Elevated physical anhedonia associated with deficits in verbal functions, but this was not related to genetic liability to schizophrenia. In conclusion, social and physical anhedonia did not seem to mediate neuropsychological deficits of schizophrenia family members.


Assuntos
Transtornos Cognitivos/genética , Transtornos Psicóticos/genética , Transtornos Psicóticos/psicologia , Esquizofrenia/genética , Psicologia do Esquizofrênico , Irmãos/psicologia , Adulto , Transtornos Cognitivos/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Testes Neuropsicológicos , Desempenho Psicomotor/fisiologia , Transtornos Psicóticos/complicações , Esquizofrenia/complicações , Meio Social
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